Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Kristina Brumme"'
Autor:
Kristina Brumme, Hilary A. Hewes, Rachel Richards, Marianne Gausche‐Hill, Katherine Remick, Joelle Donofrio‐Odmann
Publikováno v:
Journal of the American College of Emergency Physicians Open, Vol 3, Iss 6, Pp n/a-n/a (2022)
Abstract Study Objectives The objective of this study was to determine if there is a proximity effect of high‐acuity, pediatric‐capable emergency departments (EDs) on the weighted pediatric readiness score of neighboring general EDs and whether t
Externí odkaz:
https://doaj.org/article/bdf4ec313e454432a97a0f9ee6b9dcdf
Autor:
Sumin Koo, Brian J. Huntly, Yuan Wang, Jing Chen, Kristina Brumme, Brian Ball, Shannon L. McKinney-Freeman, Akiko Yabuuchi, Claudia Scholl, Dimple Bansal, Leonard I. Zon, Stefan Fröhling, George Q. Daley, D. Gary Gilliland, Thomas Mercher
Publikováno v:
Haematologica, Vol 95, Iss 10 (2010)
Background Cdx4 is a homeobox gene essential for normal blood formation during embryonic development in the zebrafish, through activation of posterior Hox genes. However, its role in adult mammalian hematopoiesis has not been extensively studied and
Externí odkaz:
https://doaj.org/article/3426c154afe24aab91cd33e354c53745
Publikováno v:
Hematology/Oncology Clinics of North America. 26:1065-1081
Myeloproliferative neoplasm (MPN) animal models accurately re-capitulate human disease in mice and have been an important tool for the study of MPN biology and therapy. Transplantation of BCR-ABL transduced bone marrow cells into irradiated syngeneic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a76664e2ead5299bb0b1459e668ee1be
https://doi.org/10.1016/j.hoc.2012.07.007
https://doi.org/10.1016/j.hoc.2012.07.007
Autor:
Wendy B. London, Chad E. Harris, Rutesh Vyas, Thorsten M. Schlaeger, Alex Devine, Kelly Strait, Axel Schambach, Lisa A. Moreau, David A. Williams, Elke Grassman, Alan D. D'Andrea, George Q. Daley, Kalindi Parmar, Michael D. Milsom, In-Hyun Park, Kristina Brumme, Lars U.W. Müller
Publikováno v:
Blood. 119:5449-5457
Fanconi anemia (FA) is a recessive syndrome characterized by progressive fatal BM failure and chromosomal instability. FA cells have inactivating mutations in a signaling pathway that is critical for maintaining genomic integrity and protecting cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2b61d0ef6b034dff991c50dbc29a9f5
https://doi.org/10.1182/blood-2012-02-408674
https://doi.org/10.1182/blood-2012-02-408674
Autor:
David T. Scadden, Cristina Lo Celso, Kristina Brumme, Subhanjan Mondal, Hongbo R. Luo, Adrienne M. Dorrance, Francesca Ferraro, Abel Sanchez-Aguilera, Yun-Jung Lee, David A. Williams, Chaekyun Kim
Publikováno v:
Proceedings of the National Academy of Sciences. 108:9607-9612
Engraftment and maintenance of hematopoietic stem and progenitor cells (HSPC) depend on their ability to respond to extracellular signals from the bone marrow microenvironment, but the critical intracellular pathways integrating these signals remain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7530dc2a7a63ac77c63c0eed5b7516df
https://doi.org/10.1073/pnas.1102018108
https://doi.org/10.1073/pnas.1102018108
Autor:
Stefan Fröhling, Yuan Wang, Shannon McKinney-Freeman, Leonard I. Zon, Brian J. P. Huntly, Dimple Bansal, George Q. Daley, Claudia Scholl, D. Gary Gilliland, Akiko Yabuuchi, Sumin Koo, Jing Chen, Thomas Mercher, Brian Ball, Kristina Brumme
Publikováno v:
Haematologica. 95:1642-1650
Cdx4 is a homeobox gene essential for normal blood formation during embryonic development in the zebrafish, through activation of posterior Hox genes. However, its role in adult mammalian hematopoiesis has not been extensively studied and its require
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9b85deb0909fb1e49da5d3f515895b0
https://doi.org/10.3324/haematol.2010.023168
https://doi.org/10.3324/haematol.2010.023168
Autor:
Ross L. Levine, Benjamin L. Ebert, Kristina Brumme, Edwin Chen, Ann Mullally, Luke Poveromo, Lawrence J. Breyfogle, Emily A. Rosen, Shannon Elf, Rebekka K. Schneider, Amy Ko
Publikováno v:
Blood. 125(2)
Signaling mutations (eg, JAK2V617F) and mutations in genes involved in epigenetic regulation (eg, TET2) are the most common cooccurring classes of mutations in myeloproliferative neoplasms (MPNs). Clinical correlative studies have demonstrated that T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70a3c7b43c44d2c5c450f063092d40ce
https://pubmed.ncbi.nlm.nih.gov/25573967
https://pubmed.ncbi.nlm.nih.gov/25573967
Publikováno v:
Experimental Hematology. 40:487-498.e3
Ubiquitously transcribed tetratricopeptide repeat, X chromosome (UTX), an H3K27Me2/3 demethylase, has been implicated in development, self-renewal, and differentiation of various organs and embryonic stem cells through chromatin modifications and tra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a3e0727c0a2028ff8e9b88e3bd2df2a
https://doi.org/10.1016/j.exphem.2012.01.017
https://doi.org/10.1016/j.exphem.2012.01.017
Autor:
In-Hyun Park, Elke Grassman, Thorsten M. Schlaeger, Axel Schambach, Kristina Brumme, Chad E. Harris, Kalindi Parmar, George Q. Daley, David A. Williams, Rutesh Vyas, Lars Mueller, Michael D. Milsom, Alan D. D'Andrea, London Wendy, Kelly Strait, Alex Devine
Publikováno v:
Blood. 118:672-672
Abstract 672 Fanconi anemia (FA) is a recessive syndrome characterized by progressive fatal bone marrow failure and chromosomal instability. FA cells have inactivating mutations in a signaling pathway that is critical for maintaining genomic integrit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed7675c358d3d7a502ee5adbafad46dc
https://doi.org/10.1182/blood.v118.21.672.672
https://doi.org/10.1182/blood.v118.21.672.672
Autor:
Steven W. Lane, Fatima Al-Shahrour, Kristina Brumme, Alan H. Shih, Luke Poveromo, Ann Mullally, Iannis Aifantis, Benjamin L. Ebert, Ross L. Levine
Publikováno v:
Blood. 118:614-614
Abstract 614 Myeloproliferative neoplasms (MPN) are clonal disorders of hematopoiesis but the mechanisms of clonal dominance in these diseases are poorly understood. The JAK2V617F mutation is found in the majority of patients with MPN and is sufficie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca644b7c2665f81cad254fcff5d9e55b
https://doi.org/10.1182/blood.v118.21.614.614
https://doi.org/10.1182/blood.v118.21.614.614