Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Kristina Bonham"'
Autor:
Atsushi Kubo, Robert Stull, Mitsuaki Takeuchi, Kristina Bonham, Valerie Gouon-Evans, Masayuki Sho, Masayuki Iwano, Yoshihiko Saito, Gordon Keller, Ralph Snodgrass
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24058 (2011)
In order to define the molecular mechanisms regulating the specification and differentiation of pancreatic β-islet cells, we investigated the effect of upregulating Pdx1 and Ngn3 during the differentiation of the β-islet-like cells from murine embr
Externí odkaz:
https://doaj.org/article/9bfa7a7f023d48d2a86ab1e9d78593ab
Publikováno v:
Toxicology and applied pharmacology. 437
Many small molecule kinase inhibitors (SMKIs), used predominantly in cancer therapy, have been implicated in serious clinical cardiac adverse events, which means that traditional preclinical drug development assays were not sufficient for identifying
Autor:
Kristina Bonham, Loren J. Field, Els Henckaerts, Eric Adler, Geoffrey W. Abbott, Marion Kennedy, R. Michael Linden, Mark H. Soonpaa, Lei Yang, Torsten K. Roepke, Gordon Keller, Steven J. Kattman
Publikováno v:
Nature. 453:524-528
The functional heart is comprised of distinct mesoderm-derived lineages including cardiomyocytes, endothelial cells and vascular smooth muscle cells. Studies in the mouse embryo and the mouse embryonic stem cell differentiation model have provided ev
Autor:
Kristina Bonham, Masayuki Iwano, Atsushi Kubo, Masayuki Sho, Ralph Snodgrass, Valerie Gouon-Evans, Gordon Keller, Robert Stull, Yoshihiko Saito, Mitsuaki Takeuchi
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24058 (2011)
PLoS ONE
PLoS ONE
In order to define the molecular mechanisms regulating the specification and differentiation of pancreatic β-islet cells, we investigated the effect of upregulating Pdx1 and Ngn3 during the differentiation of the β-islet-like cells from murine embr