Quantitative Evaluation of Stem-like Markers of Human Glioblastoma Using Single-Cell RNA Sequencing Datasets

Autor: Yue He, Kristina B. V. Døssing, Ane Beth Sloth, Xuening He, Maria Rossing, Andreas Kjaer

Publikováno v: He, Y, Døssing, K B V, Sloth, A B, He, X, Rossing, M & Kjaer, A 2023, ' Quantitative Evaluation of Stem-like Markers of Human Glioblastoma Using Single-Cell RNA Sequencing Datasets ', Cancers, vol. 15, no. 5, 1557 . https://doi.org/10.3390/cancers15051557
Cancers
Volume 15
Issue 5
Pages: 1557

Targeting glioblastoma (GBM) stem-like cells (GSCs) is a common interest in both the laboratory investigation and clinical treatment of GBM. Most of the currently applied GBM stem-like markers lack validation and comparison with common standards rega

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f44d6831a563eacc7572efa0da3fcd76
https://doi.org/10.3390/cancers15051557

In vivo detection of urokinase-type plasminogen activator receptor (uPAR) expression in arterial atherogenesis using [

Autor: Harshvardhan A, Khare, Kristina B V, Døssing, Lars, Ringgaard, Esben, Christensen, Laerke, Urbak, Henrik, Sillesen, Rasmus S, Ripa, Tina, Binderup, Sune F, Pedersen, Andreas, Kjaer

Publikováno v: Atherosclerosis. 352

Urokinase-type plasminogen activator receptor (uPAR) is associated with extracellular matrix (ECM) degradation and cancer aggressiveness. Its role in arterial atherogenesis as a molecular imaging target is not well-established. The aim of this study

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::fc19ffdbf724df42575cb534ac0216f2
https://pubmed.ncbi.nlm.nih.gov/35623934

Down-Regulation of miR-129-5p and the let-7 Family in Neuroendocrine Tumors and Metastases Leads to Up-Regulation of Their Targets Egr1, G3bp1, Hmga2 and Bach1

Autor: Ole Winther, Andreas Kjaer, Kristina B V Døssing, Ulrich Knigge, Birgitte Federspiel, Lennart Friis-Hansen, Anders Jacobsen, Maria Rossing, Bogumil Kaczkowski, Tina Binderup

Publikováno v: Genes, Vol 6, Iss 1, Pp 1-21 (2014)
Genes
Volume 6
Issue 1
Pages 1-21
Døssing, K B V, Binderup, T, Kaczkowski, B, Jacobsen, A M B, Rossing, M, Winther, O, Federspiel, B, Knigge, U, Kjær, A & Friis-Hansen, L 2015, ' Down-regulation of miR-129-5p and the let-7 family in neuroendocrine tumors and metastases leads to up-regulation of their targets Egr1, G3bp1, Hmga2 and Bach1 ', Genes, vol. 6, no. 1, pp. 1-21 . https://doi.org/10.3390/genes6010001
Dossing, K B V, Binderup, T, Kaczkowski, B, Jacobsen, A, Rossing, M, Winther, O, Federspiel, B, Knigge, U, Kjær, A & Friis-Hansen, L 2014, ' Down-Regulation of miR-129-5p and the let-7 Family in Neuroendocrine Tumors and Metastases Leads to Up-Regulation of Their Targets Egr1, G3bp1, Hmga2 and Bach1 ', Genes, vol. 6, no. 1, pp. 1-21 . https://doi.org/10.3390/genes6010001

Expression of miRNAs in Neuroendocrine Neoplasms (NEN) is poorly characterized. We therefore wanted to examine the miRNA expression in Neuroendocrine Tumors (NETs), and identify their targets and importance in NET carcinogenesis. miRNA expression in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08688ff9dab46e352a5b2793a3e8a11a
http://www.mdpi.com/2073-4425/6/1/1

Alternative poladenylation of tumor suppressor genes in small intestinal neuroendocrine tumors

Autor: Lennart Friis-Hansen, Kristina B V Døssing, Anders Krogh, Andreas Kjaer, Anders Rehfeld, Mireya Plass, Ulrich Knigge

Publikováno v: Frontiers in Endocrinology, Vol 5 (2014)
Frontiers in Endocrinology

The tumorigenesis of small intestinal neuroendocrine tumors is poorly understood. Recent studies have associated alternative polyadenylation with proliferation, cell transformation and cancer. Polyadenylation is the process in which the pre-mRNA is c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c27c84d1d42aba858ff4fe25787041d3
http://journal.frontiersin.org/Journal/10.3389/fendo.2014.00046/full

Human native lipoprotein-induced de novo DNA methylation is associated with repression of inflammatory genes in THP-1 macrophages

Autor: Marie Wickström-Lindholm, Gertrud Lund, Carlos A. Aguilar-Salinas, Kazimierz Wrobel, Finn Cilius Nielsen, Yolanda Alvarado-Caudillo, Katarzyna Wrobel, Manel Esteller, Dalia Rodríguez-Ríos, Ruben Rangel-Salazar, Martha O Solís-Martínez, Silvio Zaina, Emmanuel Labourier, Kristina B V Døssing

Publikováno v: BMC Genomics; 12 (2011)
BMC Genomics, Vol 12, Iss 1, p 582 (2011)
BMC Genomics
Recercat. Dipósit de la Recerca de Catalunya
instname
Dipòsit Digital de la UB
Universidad de Barcelona

Background We previously showed that a VLDL- and LDL-rich mix of human native lipoproteins induces a set of repressive epigenetic marks, i.e. de novo DNA methylation, histone 4 hypoacetylation and histone 4 lysine 20 (H4K20) hypermethylation in THP-1

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::014ee92d2e8043d9af9b3f953de251d9
https://lup.lub.lu.se/record/2348592