Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Kristina A. Sharlo"'
Autor:
Kristina A. Sharlo, Irina D. Lvova, Sergey A. Tyganov, Ksenia V. Sergeeva, Vitaly Y. Kalashnikov, Ekaterina P. Kalashnikova, Timur M. Mirzoev, Grigoriy R. Kalamkarov, Tatiana F. Shevchenko, Boris S. Shenkman
Publikováno v:
Current Issues in Molecular Biology, Vol 45, Iss 7, Pp 5613-5630 (2023)
Skeletal muscle disuse leads to pathological muscle activity as well as to slow-to-fast fiber-type transformation. Fast-type fibers are more fatigable than slow-type, so this transformation leads to a decline in muscle function. Prochlorperazine inje
Externí odkaz:
https://doaj.org/article/7c81d0e0556646f9bd2e1b8fbd1b2b27
Autor:
Kristina A. Sharlo, Irina D. Lvova, Sergey A. Tyganov, Ksenia A. Zaripova, Svetlana P. Belova, Tatiana Y. Kostrominova, Boris S. Shenkman, Tatiana L. Nemirovskaya
Publikováno v:
Biomolecules, Vol 13, Iss 9, p 1354 (2023)
Skeletal muscle abnormalities and atrophy during unloading are accompanied by the accumulation of excess calcium in the sarcoplasm. We hypothesized that calcium accumulation may occur, among other mechanisms, due to the inhibition of sarco/endoplasmi
Externí odkaz:
https://doaj.org/article/83c62eaa9271412c94f8a1a79dbb052a
Autor:
Kristina A. Sharlo, Inna I. Paramonova, Irina D. Lvova, Natalia A. Vilchinskaya, Anna E. Bugrova, Tatiana F. Shevchenko, Grigoriy R. Kalamkarov, Boris S. Shenkman
Publikováno v:
Frontiers in Physiology, Vol 11 (2020)
It is known that nitric oxide (NO) may affect myosin heavy chain (MyHC) isoform mRNA transcription in skeletal muscles. The content of NO in soleus muscles decreases during rat hindlimb unloading as well as slow MyHC mRNA transcription. We aimed to d
Externí odkaz:
https://doaj.org/article/12c8feafe1cf41a8bde5ea9da98f7146
Autor:
Sergey A. Tyganov, Ekaterina P. Mochalova, Svetlana P. Belova, Kristina A. Sharlo, Sergey V. Rozhkov, Natalia A. Vilchinskaya, Inna I. Paramonova, Timur M. Mirzoev, Boris S. Shenkman
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
It is known that plantar mechanical stimulation (PMS) is able to attenuate unloading-induced skeletal muscle atrophy and impaired muscle function. However, molecular mechanisms underlying the effect of PMS on skeletal muscle during unloading remain u
Externí odkaz:
https://doaj.org/article/f78966b292b34363af1b1afd20075cea
Autor:
Shenkman, Kristina A. Sharlo, Irina D. Lvova, Sergey A. Tyganov, Ksenia V. Sergeeva, Vitaly Y. Kalashnikov, Ekaterina P. Kalashnikova, Timur M. Mirzoev, Grigoriy R. Kalamkarov, Tatiana F. Shevchenko, Boris S.
Publikováno v:
Current Issues in Molecular Biology; Volume 45; Issue 7; Pages: 5613-5630
Skeletal muscle disuse leads to pathological muscle activity as well as to slow-to-fast fiber-type transformation. Fast-type fibers are more fatigable than slow-type, so this transformation leads to a decline in muscle function. Prochlorperazine inje
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::4f8c313acbe2ae8ce976c5c7b24f4b27
Publikováno v:
Acta Astronautica. 186:252-258
Skeletal muscle inactivity due to real or simulated microgravity results in a significant atrophy of muscle fibers. One of the key causes of disuse atrophy is a decrease in the rate of muscle protein synthesis (MPS). MPS is dependent not only on tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c53dd6dbf7961ec8d16ffcccbe6a3e6
https://doi.org/10.1016/j.actaastro.2021.05.036
https://doi.org/10.1016/j.actaastro.2021.05.036
Autor:
Ivan Y. Melnikov, Sergey A. Tyganov, Kristina A. Sharlo, Anna D. Ulanova, Ivan M. Vikhlyantsev, Timur M. Mirzoev, Boris S. Shenkman
In mammals, prolonged mechanical unloading results in a significant decrease in passive stiffness of postural muscles. The nature of this phenomenon remains unclear. The aim of the present study was to investigate possible causes for a reduction in r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3d7dfa80c91dc24786e7535a30a55e52
https://doi.org/10.21203/rs.3.rs-1592755/v1
https://doi.org/10.21203/rs.3.rs-1592755/v1
Publikováno v:
Biochemistry (Moscow), Supplement Series A: Membrane and Cell Biology. 14:242-248
Gravitational unloading leads to a slow-to-fast shift in the myosin phenotype. The reason for these changes is a decrease in the expression of the genes encoding heavy chains of myosin (MyHC) of the slow type, and an increase in the expression of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9d8d78c4c303b9e686d0314112803cda
https://doi.org/10.1134/s1990747820020099
https://doi.org/10.1134/s1990747820020099
Autor:
Kristina A. Sharlo, Irina D. Lvova, Svetlana P. Belova, Ksenia A. Zaripova, Boris S. Shenkman, Tatiana L. Nemirovskaya
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 1; Pages: 503
Muscle unloading leads to signaling alterations that cause muscle atrophy and weakness. The cellular energy sensor AMPK can regulate myofiber-type shift, calcium-dependent signaling and ubiquitin-proteasome system markers. We hypothesized that the pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c357e1d1e81fbd325617f481a1cf8fb7
https://doi.org/10.3390/ijms24010503
https://doi.org/10.3390/ijms24010503
Publikováno v:
Archives of Biochemistry and Biophysics. 730:109411
Prolonged inactivity of skeletal muscles due to limb immobilization, bedrest, and exposure to microgravity results in a significant muscle atrophy. Inactivity-induced muscle atrophy is caused by a downregulation of protein synthesis (PS) and increase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e1c9c85707e36195109ad12e95da68e4
https://doi.org/10.1016/j.abb.2022.109411
https://doi.org/10.1016/j.abb.2022.109411