Zobrazeno 1 - 10
of 83
pro vyhledávání: '"Kristina A. Harris"'
Autor:
Qian Xiao, Joseph Mears, Aparna Nathan, Kazuyoshi Ishigaki, Yuriy Baglaenko, Noha Lim, Laura A. Cooney, Kristina M. Harris, Mark S. Anderson, David A. Fox, Dawn E. Smilek, James G. Krueger, Soumya Raychaudhuri
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Psoriasis is a chronic, systemic inflammatory condition primarily affecting skin. While the role of the immune compartment (e.g., T cells) is well established, the changes in the skin compartment are more poorly understood. Using longitudina
Externí odkaz:
https://doaj.org/article/dbc9e298d8244b0593bbd1a55d0a25b0
Autor:
Eoin F. McKinney, Iona Cuthbertson, Kristina M. Harris, Dawn E. Smilek, Christopher Connor, Giulia Manferrari, Edward J. Carr, Scott S. Zamvil, Kenneth G. C. Smith
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-9 (2021)
A better understanding of how multiple sclerosis (MS) can relapse and remit is needed for the identification of biomarkers and better therapeutics. Here the authors identify a CD8 + NK cell population in patients with relapsing remitting MS and valid
Externí odkaz:
https://doaj.org/article/a9f8d3a2bb3e4843b96a53187d7c017b
Autor:
Alvise Berti, Sophie Hillion, Amber M. Hummel, Young Min Son, Nedra Chriti, Tobias Peikert, Eva M. Carmona, Wayel H. Abdulahad, Peter Heeringa, Kristina M. Harris, E. William St. Clair, Paul Brunetta, Fernando C. Fervenza, Carol A. Langford, Cees G.M. Kallenberg, Peter A. Merkel, Paul A. Monach, Philip Seo, Robert F. Spiera, John H. Stone, Guido Grandi, Jie Sun, Jacques-Olivier Pers, Ulrich Specks, Divi Cornec, for the RAVE-ITN Research Group
Publikováno v:
JCI Insight, Vol 6, Iss 22 (2021)
BACKGROUND Little is known about the autoreactive B cells in antineutrophil cytoplasmic antibody–associated (ANCA-associated) vasculitis (AAV). We aimed to investigate tolerance checkpoints of circulating antigen-specific proteinase 3–reactive (P
Externí odkaz:
https://doaj.org/article/17108e393aed484eae0eb4f26d7643a8
Autor:
Kristina Doing-Harris, Bruce E. Bray, Anne Thackeray, Rashmee U. Shah, Yijun Shao, Yan Cheng, Qing Zeng-Treitler, Jennifer H. Garvin, Charlene Weir
Publikováno v:
Journal of Biomedical Semantics, Vol 10, Iss 1, Pp 1-16 (2019)
Abstract Background A Cardiac-centered Frailty Ontology can be an important foundation for using NLP to assess patient frailty. Frailty is an important consideration when making patient treatment decisions, particularly in older adults, those with a
Externí odkaz:
https://doaj.org/article/0dc9ab3853c04cfa90c4f19044b49532
Autor:
Alvise Berti, Sophie Hillion, Maximilian F. Konig, Marta Casal Moura, Amber M. Hummel, Eva Carmona, Tobias Peikert, Fernando C. Fervenza, Cees G.M. Kallenberg, Carol A. Langford, Peter A. Merkel, Paul A. Monach, Philip Seo, Robert F. Spiera, Paul Brunetta, E. William St. Clair, Kristina M. Harris, John H. Stone, Guido Grandi, Jacques‐Olivier Pers, Ulrich Specks, Divi Cornec
Publikováno v:
Arthritis & Rheumatology. 75:736-747
Autor:
Elliott D. SoRelle, Ellora Haukenfrers, Vaibhav Jain, Karen Abramson, Emily Hocke, Laura A. Cooney, Kristina M. Harris, Scott S. Zamvil, Simon G. Gregory, Micah A. Luftig
Expansion and pathogenicity of CD19+/CD20+/CD11c+/T-bet+atypical B cells (ABCs) are hallmarks of numerous autoimmune disorders and chronic infections. In many such cases Epstein-Barr virus (EBV) is another associated or etiologic factor, though EBV i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a568ecaa41d494b73b417c140eed3245
https://doi.org/10.1101/2023.02.26.23286433
https://doi.org/10.1101/2023.02.26.23286433
Publikováno v:
Frontiers in Immunology, Vol 9 (2018)
Autoimmunity represents a broad category of diseases that involve a variety of organ targets and distinct autoantigens. For patients with autoimmune diseases who fail to respond to approved disease-modifying treatments, autologous hematopoietic stem
Externí odkaz:
https://doaj.org/article/f1a9483772774ecf9c4c2da0e2eda2bf
Autor:
Qian Xiao, Joseph Mears, Aparna Nathan, Kazuyoshi Ishigaki, Yuriy Baglaenko, Noha Lim, Laura A. Cooney, Kristina M. Harris, Mark Anderson, David A. Fox, Dawn E. Smilek, James G. Krueger, Soumya Raychaudhuri
BackgroundPsoriasis is a chronic, systemic inflammatory condition, primarily affecting skin and joints. It is an immune-mediated disease driven by IL-17-producing T cells in the skin. However, epidermal cells such as keratinocytes are now also recogn
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9520b950789c6f67f315dc891e29cbf9
https://doi.org/10.1101/2022.10.14.22281091
https://doi.org/10.1101/2022.10.14.22281091
Autor:
Alvise, Berti, Sophie, Hillion, Maximilian F, Konig, Marta, Casal Moura, Amber M, Hummel, Eva, Carmona, Tobias, Peikert, Fernando C, Fervenza, Cees G M, Kallenberg, Carol A, Langford, Peter A, Merkel, Paul A, Monach, Philip, Seo, Robert F, Spiera, Paul, Brunetta, E William, St Clair, Kristina M, Harris, John H, Stone, Guido, Grandi, Jacques-Olivier, Pers, Ulrich, Specks, Divi, Cornec
Publikováno v:
Arthritisrheumatology (Hoboken, N.J.).
Autoreactive B cells are responsible for ANCA production in ANCA-associated vasculitis (AAV). Rituximab depletes circulating B cells including autoreactive ones. We aimed to evaluate changes and associations with relapse of the circulating autoreacti
Autor:
Wendy Gao, Margie Byron, Betty Diamond, Diane L. Kamen, Maria Dall'Era, Cynthia Aranow, Anca D. Askanase, Amit Saxena, Susan A. Boackle, Kristin Ryker, Linna Ding, Patti Tosta, Sai Kanaparthi, Kristina M. Harris, Samir V. Parikh, Kyriakos A. Kirou, Maureen McMahon, S. Sam Lim, William F. Pendergraft, David Wofsy, Dawn E. Smilek, W. Winn Chatham, Susan Malkiel, Amber S. Podoll, Bradley Marder, Y Atisha-Fregoso, William T. Barry, David R. Karp
Publikováno v:
Arthritis & Rheumatology (Hoboken, N.j.)
Arthritis Rheumatol
Arthritis Rheumatol
Objective To assess the safety, mechanism of action, and preliminary efficacy of rituximab followed by belimumab in the treatment of refractory lupus nephritis (LN). Methods In a multicenter, randomized, open-label clinical trial, 43 patients with re