Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Kristina, Keuper"'
Publikováno v:
European Journal of Cell Biology, Vol 103, Iss 2, Pp 151394- (2024)
The nuclear envelope (NE) is a critical component in maintaining the function and structure of the eukaryotic nucleus. The NE and lamina are disassembled during each cell cycle to enable an open mitosis. Nuclear architecture construction and deconstr
Externí odkaz:
https://doaj.org/article/334aa33cb31d446cbf952760a062022c
Autor:
Maja Kneissig, Kristina Keuper, Mirjam S de Pagter, Markus J van Roosmalen, Jana Martin, Hannah Otto, Verena Passerini, Aline Campos Sparr, Ivo Renkens, Fenna Kropveld, Anand Vasudevan, Jason M Sheltzer, Wigard P Kloosterman, Zuzana Storchova
Publikováno v:
eLife, Vol 8 (2019)
Cancer cells often harbor chromosomes in abnormal numbers and with aberrant structure. The consequences of these chromosomal aberrations are difficult to study in cancer, and therefore several model systems have been developed in recent years. We sho
Externí odkaz:
https://doaj.org/article/574814c022834ba19e0b5bb4d7e9d020
Publikováno v:
Letters in Drug Design & Discovery. 18:872-883
Background: Coronavirus disease-19 (COVID-19) is a newly emerged pandemic leading to a state of international alert and leaving millions of infections and thousands of deaths all over the world. Analysis of statistics and epidemiological data for the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9fd6e33b75b68407c532e1b9a5850961
https://doi.org/10.2174/1570180818666210528153844
https://doi.org/10.2174/1570180818666210528153844
Autor:
Mohamed Ma, El-Sokkary, Ahmed M, El-Baz, Rasha M, El-Morsi, Kristina, Keuper, Salah, El-Hawary, Ahmed, Shata, Galal, Yahya
Publikováno v:
Pakistan journal of pharmaceutical sciences. 35(2)
The coronavirus pandemic 2019 (COVID-19) is changing the world and reshape all aspects of life. Side by side to global efforts to develop potential vaccines and effective drugs against COVID-19, clinical parameters scanning the prognosis of COVID-19
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4fa363bcbc9b065a7d7051c959524ca5
https://pubmed.ncbi.nlm.nih.gov/35642394
https://pubmed.ncbi.nlm.nih.gov/35642394
Autor:
Kavya Prasad, Mathew Bloomfield, Hagai Levi, Kristina Keuper, Sara V. Bernhard, Nicolaas C. Baudoin, Gil Leor, Yonatan Eliezer, Maybelline Giam, Cheng Kit Wong, Giulia Rancati, Zuzana Storchová, Daniela Cimini, Uri Ben-David
Publikováno v:
Cancer Res
Aneuploidy is a hallmark of cancer with tissue-specific prevalence patterns that suggest it plays a driving role in cancer initiation and progression. However, the contribution of aneuploidy to tumorigenesis depends on both cellular and genomic conte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68879913814bc15d468354095253ac25
https://europepmc.org/articles/PMC9069772/
https://europepmc.org/articles/PMC9069772/
Autor:
Sara Vanessa Bernhard, Katarzyna Seget-Trzensiok, Christian Kuffer, Dragomir B. Krastev, Lisa-Marie Stautmeister, Mirko Theis, Kristina Keuper, Jan-Eric Boekenkamp, Maik Kschischo, Frank Buchholz, Zuzana Storchova
Publikováno v:
Cellular oncology
Background Whole genome doubling is a frequent event during cancer evolution and shapes the cancer genome due to the occurrence of chromosomal instability. Yet, erroneously arising human tetraploid cells usually do not proliferate due to p53 activati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::610fb6ad503322b67925826f6a5ec91f
https://pubmed.ncbi.nlm.nih.gov/34962618
https://pubmed.ncbi.nlm.nih.gov/34962618
Autor:
Simon Gemble, René Wardenaar, Kristina Keuper, Nishit Srivastava, Maddalena Nano, Anne-Sophie Macé, Andréa E. Tijhuis, Sara Vanessa Bernhard, Diana C.J. Spierings, Anthony Simon, Oumou Goundiam, Helfrid Hochegger, Matthieu Piel, Floris Foijer, Zuzana Storchová, Renata Basto
Doubling of the full chromosome content -whole genome duplications (WGDs)- is frequently found in human cancers and is responsible for the rapid evolution of genetically unstable karyotypes 1–3. It has previously been established that WGDs fuel chr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f90ba2da6a7b518a6098617fd789b4b
https://doi.org/10.1101/2021.07.16.452672
https://doi.org/10.1101/2021.07.16.452672
Autor:
Simon Gemble, René Wardenaar, Kristina Keuper, Nishit Srivastava, Maddalena Nano, Anne-Sophie Macé, Andréa E. Tijhuis, Sara Vanessa Bernhard, Diana C. J. Spierings, Anthony Simon, Oumou Goundiam, Helfrid Hochegger, Matthieu Piel, Floris Foijer, Zuzana Storchová, Renata Basto
Publikováno v:
Nature. 608:E27-E27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b390e6282bd997583a1531781af67604
https://doi.org/10.1038/s41586-022-05099-w
https://doi.org/10.1038/s41586-022-05099-w
Autor:
Kristina Keuper, Mathew Bloomfield, Hagai Levi, Prasad K, Nicolaas C. Baudoin, Zuzana Storchova, Cheng Kit Wong, Sara Vanessa Bernhard, Uri Ben-David, Daniela Cimini, Leor G, Maybelline Giam, Giulia Rancati
Aneuploidy – a hallmark of cancer – has tissue-specific recurrence patterns suggesting it plays a driving role in cancer initiation and progression. However, the contribution of aneuploidy to tumorigenesis depends on the cellular and genomic cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08cc80b27698fa60462971c7a94cf0d7
https://doi.org/10.1101/2021.05.05.442712
https://doi.org/10.1101/2021.05.05.442712
Autor:
Simon Gemble, René Wardenaar, Kristina Keuper, Nishit Srivastava, Maddalena Nano, Anne-Sophie Macé, Andréa E. Tijhuis, Sara Vanessa Bernhard, Diana C. J. Spierings, Anthony Simon, Oumou Goundiam, Helfrid Hochegger, Matthieu Piel, Floris Foijer, Zuzana Storchová, Renata Basto
Publikováno v:
Nature, 604. Nature Publishing Group
Diploid and stable karyotypes are associated with health and fitness in animals. By contrast, whole-genome duplications—doublings of the entire complement of chromosomes—are linked to genetic instability and frequently found in human cancers1–3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e136cd3322373cb206525c39c41a6676
https://doi.org/10.1038/s41586-022-04578-4
https://doi.org/10.1038/s41586-022-04578-4