Výsledky vyhledávání - "Kristin Wynne"

Immune evasion strategies of pediatric precursor-B acute lymphoblastic leukemia after allogeneic bone marrow transplantation—a case study

Autor: Draga Barbaric, Soudabeh Aslanian, Kristin Wynne, Mason Bond, Gregor S. D. Reid

Publikováno v: Leukemia Research. 29:711-714

Bone marrow transplantation (BMT) is the primary curative option for refractory/relapsed pediatric acute lymphoblastic leukemia. Although post-transplantation relapse remains a frequent cause of transplantation failure, the mechanisms underlying this

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10d5339fbf0e90b4b54e83cb4e833f4f
https://doi.org/10.1016/j.leukres.2005.01.002

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Differential immune effects mediated by Toll-like receptors stimulation in precursor B-cell acute lymphoblastic leukaemia

Autor: Hiromi Shimizu, Darko Curman, Kevin She, Sophie L. Corthals, Kristy Garbutt, Gregor S. D. Reid, Kristin Wynne

Publikováno v: British journal of haematology. 132(4)

Acute lymphoblastic leukaemia (ALL) is the most common paediatric malignancy and, although current therapy is widely effective, relapse remains a significant clinical problem for which new treatment strategies are required. The ligation of Toll-like

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8575a3ca42ede0194b68e5f792fafa99
https://pubmed.ncbi.nlm.nih.gov/16412017

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Alteration of Pre-B Acute Lymphoblastic Leukemia Immunogenicity by TLR Stimulation

Autor: Gregor S. D. Reid, Kristy Garbutt, Sophie L. Corthals, Kevin She, Darko Curman, Kristin Wynne

Publikováno v: Journal of Pediatric Hematology/Oncology. 27:468-469

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::de3fa9918e2f8888a06bc1029a739b28
https://doi.org/10.1097/01.mph.0000188529.78759.9b

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Stimulation of Precursor-B Acute Lymphoblastic Leukemia Cells with Toll-Like Receptor Ligands Alters Their Immunogenicity

Autor: Darko Curman, Kristy Garbutt, Joan Mathers, Kevin She, Gregor S. D. Reid, Heather Wildgrove, Kristin Wynne

Publikováno v: Blood. 104:1887-1887

Pediatric pre-B acute lymphoblastic leukemia is the most common childhood cancer. Although current therapies achieve a high rate of remission, relapse of pre-B ALL remains a significant clinical challenge and new forms of therapy are needed. The graf

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4f722b4d393f6f210b3646f74d2c25c9
https://doi.org/10.1182/blood.v104.11.1887.1887

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Early and Late Extensive Chronic Graft-versus-Host Disease in Children Is Characterized by Different Th1/Th2 Cytokine Profiles: Findings of the Children's Oncology Group Study ASCT0031

Autor: Preeti Satyanarayana, Amina Kariminia, Kristin Wynne, Jacob Rozmus, Mark Krailo, Frederick D. Goldman, Kirk R. Schultz, Andrew L. Gilman, Stephan A. Grupp

Publikováno v: Biology of Blood and Marrow Transplantation. (12):1804-1813

Numerous mechanisms underlie chronic graft-versus-host disease (cGVHD), including skewing of Th1/Th2 cytokine expression. There are biological differences between early-onset and late-onset cGVHD. To test whether different Th1/Th2 cytokines are assoc

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3dac107470fe844035bcbe2b337f1af6

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