Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Kristin Waraska"'
Autor:
Abdalla Bowirrat, Yan Meng, Kristin Waraska, Clinton T. Baldwin, Lindsay A. Farrer, Rivka Inzelberg, Robert P. Friedland
Publikováno v:
The American Journal of Human Genetics. 78(5):871-877
Several lines of evidence support for a role of angiotensin converting enzyme (ACE) in Alzheimer disease (AD). Most genetic studies have focused on an Alu insertion/deletion (I/D) polymorphism in the ACE gene (DCP1) and have yielded conflicting resul
Autor:
Marlene Oscar-Berman, Jing Cui, Robert P. Friedland, Abdalla Bowirrat, Kristin Waraska, Clinton T. Baldwin, Amos D. Korczyn, Lindsay A. Farrer
Publikováno v:
Neuropsychiatric Disease and Treatment
The angiotensin-converting enzyme (ACE), a protease involved in blood pressure regulation, has been implicated as an important candidate gene for Alzheimer's disease (AD). This study investigated whether the ACE gene insertion-deletion (ID) polymorph
Publikováno v:
Leukemia Research. 28:1125-1136
Six patients with bcr-abl positive AML or chronic myelogenous leukemia in blast crisis (CML-BC) were treated with the IMP-dehydrogenase (IMPDH) inhibitor, Tiazofurin , in a Phase-II trial. Tiazofurin was given by IV infusion (2200–2700mg/m 2 per da
Publikováno v:
Leukemia Research. 28:1137-1143
Inosine-5'-monophosphate-dehydrogenase (IMPDH) regulates the de novo synthesis of guanine ribonucleotides (GNT). IMPDH activity varies inversely with intracellular [GNT] and is linked to cellular proliferation. K562 leukemia cell growth was studied r
Autor:
Marcia S, Osburne, Brianne M, Holmbeck, Jorge, Frias-Lopez, Robert, Steen, Katherine, Huang, Libusha, Kelly, Allison, Coe, Kristin, Waraska, Andrew, Gagne, Sallie W, Chisholm
Publikováno v:
Environmental Microbiology
Exposure to solar radiation can cause mortality in natural communities of pico-phytoplankton, both at the surface and to a depth of at least 30 m. DNA damage is a significant cause of death, mainly due to cyclobutane pyrimidine dimer formation, which
Publikováno v:
Leukemia research. 28(11)
Six patients with bcr-abl positive AML or chronic myelogenous leukemia in blast crisis (CML-BC) were treated with the IMP-dehydrogenase (IMPDH) inhibitor, Tiazofurin, in a Phase-II trial. Tiazofurin was given by IV infusion (2200-2700 mg/m2 per day)
Publikováno v:
Leukemia research. 28(11)
Inosine-5'-monophosphate-dehydrogenase (IMPDH) regulates the de novo synthesis of guanine ribonucleotides (GNT). IMPDH activity varies inversely with intracellular [GNT] and is linked to cellular proliferation. K562 leukemia cell growth was studied r
Autor:
Robert P. Friedland, Amos D. Korczyn, Abdalla Bowirrat, Lindsay A. Farrer, Kristin Waraska, Clinton T. Baldwin
Publikováno v:
Human molecular genetics. 12(4)
We have observed an unusually high prevalence of dementia of the Alzheimer type (DAT) in Wadi Ara, an inbred Arab community in northern Israel comprising approximately 850 persons over the age of 60 years. Family studies revealed that more than one-t
Autor:
Kristin Waraska, Lindsay A. Farrer, Amos D. Korczyn, Robert P. Friedland, Clinton T. Baldwin, Abdalla Bowirrat
Publikováno v:
Journal of molecular neuroscience : MN. 20(3)
We have found an unusually high prevalence of Alzheimer's disease (AD) in Wadi Ara, an inbred Arab community in northern Israel. Allele frequencies of 4.5% and 3.5% were found for the apolipoprotein E e4 allele among AD cases and nondemented controls
Autor:
Diego F. Wyszynski, Paola Sebastiani, Lindsay A. Farrer, John J. Farrell, Vikki G. Nolan, Clinton T. Baldwin, Kristin Waraska, Alice Bisbee, Martin H. Steinberg, Qianli Ma
Publikováno v:
Blood. 106:74-74
A global estimation of sickle cell disease severity has been difficult to establish making the integration of clinical and laboratory abnormalities of into a predictive model of disease complications and death, an unrealized goal. A useful model migh