Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Kristin Surmann"'
Autor:
Alexander Ganske, Larissa Milena Busch, Christian Hentschker, Alexander Reder, Stephan Michalik, Kristin Surmann, Uwe Völker, Ulrike Mäder
Publikováno v:
Frontiers in Microbiology, Vol 15 (2024)
Staphylococcus aureus is a common colonizer of the skin and nares of healthy individuals, but also a major cause of severe human infections. During interaction with the host, pathogenic bacteria must adapt to a variety of adverse conditions including
Externí odkaz:
https://doaj.org/article/c3628aeca859461c9047f82a7801386d
Autor:
Björn Klabunde, André Wesener, Wilhelm Bertrams, Isabell Beinborn, Nicole Paczia, Kristin Surmann, Sascha Blankenburg, Jochen Wilhelm, Javier Serrania, Kèvin Knoops, Eslam M. Elsayed, Katrin Laakmann, Anna Lena Jung, Andreas Kirschbaum, Sven Hammerschmidt, Belal Alshaar, Nicolas Gisch, Mobarak Abu Mraheil, Anke Becker, Uwe Völker, Evelyn Vollmeister, Birke J. Benedikter, Bernd Schmeck
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract Lower respiratory tract infections caused by Streptococcus pneumoniae (Spn) are a leading cause of death globally. Here we investigate the bronchial epithelial cellular response to Spn infection on a transcriptomic, proteomic and metabolic l
Externí odkaz:
https://doaj.org/article/f53e17d7ffee4a8b866fd16db80c5bb8
Autor:
Stefanie M. Herbel, Lambert Moyon, Marvin Christ, Eslam M. Elsayed, Brian E. Caffrey, Silke Malmsheimer, Iwan Grin, Kerstin Hoffmann, Kristin Surmann, Sascha Blankenburg, Anna Lena Jung, Christina E. Herkt, Marco Borsò, Beyza Bozdag, Axel Imhof, Anke Becker, Samuel Wagner, Gert Bange, Uwe Völker, Wilhelm Bertrams, Annalisa Marsico, Bernd Schmeck
Publikováno v:
Virulence, Vol 13, Iss 1, Pp 2042-2058 (2022)
Legionella pneumophila (L.p.) is a bacterial pathogen which is a common causative agent of pneumonia. In humans, it infects alveolar macrophages and transfers hundreds of virulence factors that interfere with cellular signalling pathways and the tran
Externí odkaz:
https://doaj.org/article/3cfbe5db3b0f4145a005db5fed54388b
Autor:
Stefaniya Gencheva, Simon Dersch, Kristin Surmann, Mathias Wernet, Luis Antelo, Elke Hammer, Peter L. Graumann, Nadja Hellmann, Gottfried Unden
Publikováno v:
mSphere, Vol 7, Iss 4 (2022)
ABSTRACT Signaling of two-component systems by phosphoryl transfer requires interaction of the sensor kinase with the response regulator. Interaction of the C4-dicarboxylate-responsive and membrane-integral sensor kinase DcuS with the response regula
Externí odkaz:
https://doaj.org/article/61e4bef83dbc4ddc8b934cc7b3671dcf
Autor:
Lucille F. van Beek, Kristin Surmann, H. Bart van den Berg van Saparoea, Diane Houben, Wouter S. P. Jong, Christian Hentschker, Thomas H. A. Ederveen, Elena Mitsi, Daniela M. Ferreira, Fred van Opzeeland, Christa E. van der Gaast – de Jongh, Irma Joosten, Uwe Völker, Frank Schmidt, Joen Luirink, Dimitri A. Diavatopoulos, Marien I. de Jonge
Publikováno v:
Virulence, Vol 11, Iss 1, Pp 1310-1328 (2020)
Nasopharyngeal colonization by Streptococcus pneumoniae is a prerequisite for pneumococcal transmission and disease. Current vaccines protect only against disease and colonization caused by a limited number of serotypes, consequently allowing serotyp
Externí odkaz:
https://doaj.org/article/3e016418b8e44a38bee691ecfa6505c3
Autor:
Christina E. Herkt, Brian E. Caffrey, Kristin Surmann, Sascha Blankenburg, Manuela Gesell Salazar, Anna L. Jung, Stefanie M. Herbel, Kerstin Hoffmann, Leon N. Schulte, Wei Chen, Alexandra Sittka-Stark, Uwe Völker, Martin Vingron, Annalisa Marsico, Wilhelm Bertrams, Bernd Schmeck
Publikováno v:
mBio, Vol 11, Iss 2 (2020)
ABSTRACT Legionella pneumophila is an important cause of pneumonia. It invades alveolar macrophages and manipulates the immune response by interfering with signaling pathways and gene transcription to support its own replication. MicroRNAs (miRNAs) a
Externí odkaz:
https://doaj.org/article/f562f453df8b4591a2a3cac252c1f3ca
Autor:
Theophilos Tzaridis, Daniel Bachurski, Shu Liu, Kristin Surmann, Felix Babatz, Manuela Gesell Salazar, Uwe Völker, Michael Hallek, Ulrich Herrlinger, Ina Vorberg, Christoph Coch, Katrin S. Reiners, Gunther Hartmann
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 17, p 9211 (2021)
Extracellular vesicles (EVs) are reminiscent of their cell of origin and thus represent a valuable source of biomarkers. However, for EVs to be used as biomarkers in clinical practice, simple, comparable, and reproducible analytical methods must be a
Externí odkaz:
https://doaj.org/article/1a448b98f650422a907d11fe166ed025
Publikováno v:
BMC Microbiology, Vol 17, Iss 1, Pp 1-17 (2017)
Abstract Background The aminoglycoside antibiotic gentamicin was supposed to induce a crosstalk between the Cpx- and the Arc-two-component systems (TCS). Here, we investigated the physical interaction of the respective TCS components and compared the
Externí odkaz:
https://doaj.org/article/e7d2e6f6051549709ca5da191d346adf
Autor:
Jelle Vlaeminck, Dina Raafat, Kristin Surmann, Leen Timbermont, Nicole Normann, Bret Sellman, Willem J. B. van Wamel, Surbhi Malhotra-Kumar
Publikováno v:
Toxins, Vol 12, Iss 11, p 721 (2020)
Pneumonia is an acute pulmonary infection associated with high mortality and an immense financial burden on healthcare systems. Staphylococcus aureus is an opportunistic pathogen capable of inducing S. aureus pneumonia (SAP), with some lineages also
Externí odkaz:
https://doaj.org/article/8bc335330e62443cabfac19fd06f7de9
Autor:
Kristin Surmann, Marjolaine Simon, Petra Hildebrandt, Henrike Pförtner, Stephan Michalik, Vishnu M. Dhople, Barbara M. Bröker, Frank Schmidt, Uwe Völker
Publikováno v:
Data in Brief, Vol 7, Iss , Pp 1031-1037 (2016)
To simultaneously obtain proteome data of host and pathogen from an internalization experiment, human alveolar epithelial A549 cells were infected with Staphylococcus aureus HG001 which carried a plasmid (pMV158GFP) encoding a continuously expressed
Externí odkaz:
https://doaj.org/article/2aa80f56e5dc40ebb694279da8b98557