Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Kristin Schmerbach"'
Autor:
Christa Thoene-Reineke, Kay Rumschüssel, Kristin Schmerbach, Maxim Krikov, Christina Wengenmayer, Michael Godes, Susanne Mueller, Arno Villringer, Ulrike Steckelings, Pawel Namsolleck, Thomas Unger
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23646 (2011)
ObjectivesThe effects of AT1 receptor blocker, telmisartan, and the ACE inhibitor, ramipril, were tested head-to head and in combination on stroke prevention in hypertensive rats and on potential neuroprotection in acute cerebral ischemia in normoten
Externí odkaz:
https://doaj.org/article/38a5750eb981473a868a9e4610d8a1a3
Autor:
Kristin Schmerbach, Thiemo Pfab, Yi Zhao, Juraj Culman, Susanne Mueller, Arno Villringer, Dominik N Muller, Berthold Hocher, Thomas Unger, Christa Thoene-Reineke
Publikováno v:
PLoS ONE, Vol 5, Iss 11, p e15052 (2010)
ObjectivePre-treatment with angiotensin receptor blockers is known to improve neurological outcome after stroke. This study investigated for the first time, whether the renin inhibitor aliskiren has similar neuroprotective effects.MethodsSince aliski
Externí odkaz:
https://doaj.org/article/a64bb0513bc24d7cb3d3592a97a31ed7
Autor:
Yuan Lu, Pontus B. Persson, Erdmann Seeliger, Mauricio Sendeski, Zhi Zhao Liu, Ruisheng Liu, Kathleen Cantow, Kristin Schmerbach, Andreas Patzak, Andrea Perlewitz, Tatiana Nikitina
Publikováno v:
American Journal of Physiology-Renal Physiology. 306:F864-F872
Iodinated contrast media (CM) have adverse effects that may result in contrast-induced acute kidney injury. Oxidative stress is believed to play a role in CM-induced kidney injury. We test the hypothesis that oxidative stress and reduced nitric oxide
Autor:
U. J. F. Tietge, H. Guski, Hans-Georg Kuhn, Kristin Schmerbach, Andreas Patzak, T. Dietrich, Dominik Linz, O. Brinkmann, K. Wilfert
Publikováno v:
Acta physiologica, 211(1), 61-72. Wiley
AimAtherosclerosis is the most common cause of cardiovascular disease. The ApoB mouse is a model for human familial hypercholesterolaemia and has a lipoprotein profile similar to that of humans with atherosclerosis. Therefore, it is a suitable model
Autor:
Andreas Patzak, Kristin Schmerbach
Publikováno v:
Acta Physiologica. 209:246-249
Autor:
Christian Böhm, Kai Kappert, Heiko Funke-Kaiser, Kerstin Seidel, Frank S. Zollmann, Sebastian Kirsch, Eva Schrezenmeier, Werner Skuballa, Kristin Schmerbach, Melanie Kroh, Sabrina Klare, Thomas Unger, Petra Goldin-Lang, Sarah Bernhard
Publikováno v:
Pharmacology, 90(5-6), 307-315. S. Karger AG
Background/Aims: Putative in vitro-in vivo correlations of pharmacokinetic (PK) parameters are regarded as a prerequisite to filter hits derived from high-throughput screening (HTS) approaches for subsequent murine in vivo PK studies. Methods: In thi
Autor:
Keisuke Ishizawa, Jung Sook Suh, Maria Frosini, Masaki Imanishi, Sarah J. Mitchell, Kai Kappert, Linyong Xu, Georg Dechant, Sui-Lin Mo, Heiko Funke-Kaiser, Piero Tanganelli, Koichiro Tsuchiya, M. Zeitlinger, Ludo Willems, Josef Donnerer, Jae-Wook Oh, Z. Erdogan, A. Burian, Ingrid Liebmann, Ignacio Valencia-Hernández, Bosheng Huang, Christian Humpel, Min-Ji Song, Constanze M. Barwitz, Licht Miyamoto, Giampietro Sgaragli, José Carlos Villegas-Bedolla, Hyung-Sik Kang, Tomoyuki Nishizaki, Alessandra Larini, Shu-Feng Zhou, Jin-Jun Zhang, Geert Meyfroidt, Kisung Ko, Kerstin Seidel, Daniel Godínez-Hernández, Hyun Soo Kwak, Lorenzo Ricci, Luisa Lucas, Victoria C. Cogger, Héctor Urquiza-Marín, Yasumasa Ikeda, Yoshitaka Kihira, Gerald Zernig, Shuhei Tomita, Shoko Fujii, Sarah N. Hilmer, Ming Wei, Haeng-A. Kang, Geert Maleux, Yuling Chen, Rafael de Cabo, Min Park, Beatrice Gorelli, Lai-Bao Sun, Kai K. Kummer, Takeshi Kanno, Xue-Nong Zou, Chris Verslype, Sarah Bernhard, Ki-Mo Lee, Blanca Nateras-Marín, José Antonio Reyes-Ramírez, Sabrina Klare, Toshiaki Tamaki, Akinobu Gotoh, Brett Jones, Janine M. Prast, Hwa-Youn Lee, Eva Schrezenmeier, Christian Böhm, Wan Kyunn Whang, Takumi Sakurada, Shuichi Hamano, Jong Mi Lee, Yuki Izawa-Ishizawa, Isabel Spriet, Aniko Huizer-Pajkos, Chung Hyo Kim, David G. Le Couteur, Massimo Valoti, Sebastian Kirsch, C. Jandrisits, Petra Goldin-Lang, Andrew J. McLachlan, Druck Reinhardt Druck Basel, Uy Dong Sohn, Thao Thanh Nguyen, Sun Young Park, Xian-Guo Liu, Lijun Cao, Neel R. Nabar, Melanie Kroh, Qiu-Lan He, Werner Skuballa, Hisao Nagaya, Frank S. Zollmann, Lixiang Wu, Hironori Taira, Thomas Unger, Kristin Schmerbach
Publikováno v:
Pharmacology. 90:I-IV
Autor:
Kristin Schmerbach, Andreas Patzak
Publikováno v:
Acta Physiologica. 210:702-704
Autor:
Thomas Unger, Frank S. Zollmann, Christa Thöne-Reineke, Jennifer Schmitz, Heiko Funke-Kaiser, Sebastian Kirsch, Daniela Zaade, Kristin Lucht, Jan H. Schefe, Petra Goldin-Lang, Yaosi Li, Kerstin Seidel, Kristin Schmerbach, Jana Reinemund, Sabrina Klare
Publikováno v:
Brain Pathology. 21:31-43
Stroke is one of the major medical burdens in industrialized countries. Animal experiments indicate that blockade of the angiotensin AT1 receptor (AT1R) improves neurological outcome after cerebral ischemia. These protective effects are partially med
Autor:
Maxim Krikov, Christian Neumann, Heide Hörtnagl, Heiko Funke-Kaiser, Arno Villringer, Ulrike Muscha Steckelings, Kay Rumschüssel, Kristin Lucht, Christa Thöne-Reineke, Kristin Schmerbach, Michael Godes, Jan H. Schefe, Pawel Namsolleck, Thomas Unger, Susanne Müller
Publikováno v:
Journal of Hypertension. 26:2426-2435
Ceftriaxone has been reported to reduce neuronal damage in amyotrophic lateral sclerosis and in an in-vitro model of neuronal ischaemia through increased expression and activity of the glutamate transporter, GLT1. We tested the effects of ceftriaxone