Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Kristin Roovers"'
Autor:
Simona Wagner, Chris J Storbeck, Kristin Roovers, Ziad Y Chaar, Piotr Kolodziej, Marlene McKay, Luc A Sabourin
Publikováno v:
PLoS ONE, Vol 3, Iss 4, p e1868 (2008)
Cell migration involves a multitude of signals that converge on cytoskeletal reorganization, essential for development, immune responses and tissue repair. Using knockdown and dominant negative approaches, we show that the microtubule-associated Ste2
Externí odkaz:
https://doaj.org/article/21df4a53cb694abca727beaa5d2b9d4b
Autor:
Ron De Jong, Mark S. Forman, Argiris Efstratiadis, Rachael M. Easton, Han Cho, Diana W. Shineman, Virginia M.-Y. Lee, Morris J. Birnbaum, Kristin Roovers, Moshe Mizrahi, Tilman Oltersdorf, Thomas Ludwig, Matthias Szabolcs
Publikováno v:
Molecular and Cellular Biology. 25:1869-1878
Studies of Drosophila and mammals have revealed the importance of insulin signaling through phosphatidylinositol 3-kinase and the serine/threonine kinase Akt/protein kinase B for the regulation of cell, organ, and organismal growth. In mammals, three
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e031cf05128d7da4e46cef04c3b6df52
https://doi.org/10.1128/mcb.25.5.1869-1878.2005
https://doi.org/10.1128/mcb.25.5.1869-1878.2005
Publikováno v:
Developmental Cell. 5(2):273-284
This article has been retracted at the request of the authors. Reason: We have recently reviewed the primary source data for our paper entitled "Nuclear Translocation of LIM Kinase Mediates Rho-Rho Kinase Regulation of Cyclin D1 Expression" [Dev. Cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::842d881a612111064a75e5120b377893
Autor:
Richard K. Assoian, Kristin Roovers
Publikováno v:
NIH guide for grants and contracts
We recently reported that Rho kinase is required for sustained ERK signaling and the consequent mid-G(1) phase induction of cyclin D1 in fibroblasts. The results presented here indicate that these Rho kinase effects are mediated by the formation of s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::caa54813384ad8560bc9d48b10d53de1
https://doi.org/10.1128/mcb.23.12.4283-4294.2003
https://doi.org/10.1128/mcb.23.12.4283-4294.2003
Autor:
Kristin Roovers, Richard K. Assoian
Publikováno v:
BioEssays. 22:818-826
Growth factors and the extracellular matrix provide the environmental cues that control the proliferation of most cell types. The binding of growth factors and matrix proteins to receptor tyrosine kinases and integrins, respectively, regulates severa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23ed968354ce96d2db019b3585d184b3
https://doi.org/10.1002/1521-1878(200009)22:9<818::aid-bies7>3.0.co
https://doi.org/10.1002/1521-1878(200009)22:9<818::aid-bies7>3.0.co
Publikováno v:
Molecular Biology of the Cell. 10:3197-3204
Cyclin D1 expression is jointly regulated by growth factors and cell adhesion to the extracellular matrix in many cell types. Growth factors are thought to regulate cyclin D1 expression because they stimulate sustained extracellular signal-regulated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38374adf17be98a1353db58a5d77371c
https://doi.org/10.1091/mbc.10.10.3197
https://doi.org/10.1091/mbc.10.10.3197
Autor:
Simona Wagner, Kristin Roovers, Chris J. Storbeck, Luc A. Sabourin, Ziad Y. Chaar, Marlene McKay, Piotr Kolodziej
Publikováno v:
PLoS ONE
PLoS ONE, Vol 3, Iss 4, p e1868 (2008)
PLoS ONE, Vol 3, Iss 4, p e1868 (2008)
Cell migration involves a multitude of signals that converge on cytoskeletal reorganization, essential for development, immune responses and tissue repair. Using knockdown and dominant negative approaches, we show that the microtubule-associated Ste2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae87ac8e52d0fbeb81729dd3a89dc185
https://pubmed.ncbi.nlm.nih.gov/18382658
https://pubmed.ncbi.nlm.nih.gov/18382658
Autor:
Kristin Roovers, Richard K. Assoian
Extensive molecular, biochemical, cell biological, and cytogenetic studies of breast cancer cell lines and breast cancer biopsies have indicated that overexpression of cyclin Dl plays an important role in breast tumor oncogenesis. Particularly, D-typ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a29ba7df38e988096220baf330ff965e
https://doi.org/10.21236/ada407447
https://doi.org/10.21236/ada407447
Autor:
Martin A. Schwartz, Richard K. Assoian, Catherine F. Welsh, Jessie Villanueva, Yun Qi Liu, Kristin Roovers
Publikováno v:
Federal Register
The expression of cyclin D1 in mid-G1 phase is associated with sustained ERK activity, and we show here that Rho is required for the sustained ERK signal. However, we also report that Rho inhibits an alternative Rac/Cdc42-dependent pathway, which res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb4a8edcb9a8eaca4da14ae19afee246
https://pubmed.ncbi.nlm.nih.gov/27737163
https://pubmed.ncbi.nlm.nih.gov/27737163
Autor:
Jessie Villanueva, Catherine F. Welsh, Martin A. Schwartz, Kristin Roovers, YunQi Liu, Richard K. Assoian
Publikováno v:
Nature Cell Biology. 11:1496-1496
In the version of the article initially published, two panels contain duplicated bands. The left hand side part of the Cdk4 northern blot in Fig. 2c is identical to the G0 panel of the ERK1/ERK2 western blot. The northern blot data with the correct d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c436891c26a13bff4918f55e04e1533e
https://doi.org/10.1038/ncb1209-1496
https://doi.org/10.1038/ncb1209-1496