Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kristin Patrick"'
Publikováno v:
The Journal of Immunology. 208:50.13-50.13
Macrophages are the primary host cell that supports the survival and replication of the intracellular bacterial pathogen Mycobacterium tuberculosis (Mtb). We are interested in how macrophage proteins are functionalized during Mtb infection. Global pr
Post-translational modification of splicing factors controls the innate immune response to infection
Autor:
Kristin Patrick
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f76e4eb55c5b1299dc48a07773962adc
https://doi.org/10.26226/morressier.5ebd45acffea6f735881ae94
https://doi.org/10.26226/morressier.5ebd45acffea6f735881ae94
Autor:
Shouvonik Sengupta, Kelsi O West, Laura Agosto-Rosa, Kristen W Lynch, Robert Watson, Kristin Patrick, Mireia Guerau-De-Arellano
Publikováno v:
The Journal of Immunology. 206:25.04-25.04
Protein Arginine Methyltransferase (PRMT) 5 catalyzes symmetric dimethylation of arginine, a post-translational modification involved in cancer and embryonic development. The mechanisms by which PRMT5 modulates T helper (Th) cell activity are still n
Publikováno v:
The Journal of Immunology. 206:97.01-97.01
To defend against invading pathogens, the macrophage innate immune response requires rapid, robust gene expression reprogramming. Innate immune genes that are induced as part of this response are regulated at many steps. While transcriptional activat
Autor:
Chi Gidley Weindel, Krystal Vail, Samantha Bell, Eduardo Martinez, Kristin Patrick, Robert Owen Watson
Publikováno v:
The Journal of Immunology. 206:112.19-112.19
Leucine-rich repeat kinase 2 (LRRK2), a multifunctional kinase linked to Parkinson’s disease (PD), has been repeatedly implicated in mycobacterial infection, although it’s function outside the nervous system is poorly understood. To create a repl
Autor:
Melanie R. Gubbels Bupp, David Gibson, Syreen Goulmamine, Amie Little, Sarah Murphy, Kristin Patrick, Timothy Thoner
Publikováno v:
The Journal of Immunology. 202:189.14-189.14
Previous work has suggested that glucocorticoids upregulate expression of the IL-7 receptor component, CD127 on peripheral T cells, even though the total number of peripheral T cells declines dramatically during malnourishment. We have proposed that
Autor:
Melanie R Gubbels Bupp, Sarah Murphy, Kristin Patrick, Timothy Thoner, R. Whitney Edwards, Seth Litvin
Publikováno v:
The Journal of Immunology. 196:204.19-204.19
The following study was undertaken to better understand the impact of short-term malnutrition on T cell homeostasis, with particular attention focused on the CD127/IL-7 signaling dynamic of peripheral T cells in mice. We report that the total number