Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Kristin M. Obrochta"'
Autor:
Joseph L. Napoli, Charles R. Krois, Candice E. Gibson, Madelyn R. Wheeler, Kristin M. Obrochta, Ishan Shah, Claire Zaversnik, Marta G. Vuckovic, Priscilla Huang, Sean P. Gordon, Airlia C.S. Thompson, Marc K. Hellerstein, Jin H. Min, Candice B. Herber, Conan S. Liu
Publikováno v:
Cell Mol Life Sci
RDH1 is one of the several enzymes that catalyze the first of the two reactions to convert retinol into all-trans-retinoic acid (atRA). Here, we show that Rdh1-null mice fed a low-fat diet gain more weight as adiposity (17% males, 13% females) than w
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e99435 (2014)
The relationship between dietary vitamin A and all-trans-retinoic acid levels in serum and tissues had not been quantified. We determined the impact of dietary vitamin A on retinoid levels in serum, liver, kidney, testis, and epididymal white adipose
Externí odkaz:
https://doaj.org/article/a881a1ce79ac410ca1d4354c7fb5c437
Publikováno v:
Journal of neurology. 267(9)
The present study evaluates serum neurofilament light chain (NfL) as a biomarker of disease features in Friedreich’s ataxia (FRDA). NfL levels from serum of 117 subjects (85 FRDA patients, 13 carriers, and 19 controls) were assayed and correlated w
Autor:
Charles R. Krois, Attilio Pingitore, Joo Yeon Ryu, Erika Cione, Joseph L. Napoli, Alexandra E. Folias, Mariarita Perri, Kristin M. Obrochta, Maureen A. Kane
Publikováno v:
Proceedings of the National Academy of Sciences. 107:21884-21889
The all-trans -retinoic acid (atRA) isomer, 9- cis -retinoic acid (9cRA), activates retinoic acid receptors (RARs) and retinoid X receptors (RXRs) in vitro. RARs control multiple genes, whereas RXRs serve as partners for RARs and other nuclear recept
Publikováno v:
Analytical biochemistry. 484
We report an ultrahigh-performance liquid chromatography tandem mass spectrometry (UHPLC-MS/MS) method to quantify all-trans-retinal in biological samples of limited size (15-35mg), which is especially advantageous for use with adipose. To facilitate