Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Kristin M. Miner"'
Autor:
Tarun N. Bhatia, Anuj S. Jamenis, Muslim Abbas, Rachel N. Clark, Kristin M. Miner, Manisha N. Chandwani, Roxanne E. Kim, William Hilinski, Lauren A. O'Donnell, Kelvin C. Luk, Yejie Shi, Xiaoming Hu, Jun Chen, Jeffrey L. Brodsky, Rehana K. Leak
Publikováno v:
Neurobiology of Disease, Vol 184, Iss , Pp 106196- (2023)
Reactive microglia are observed with aging and in Lewy body disorders, including within the olfactory bulb of men with Parkinson's disease. However, the functional impact of microglia in these disorders is still debated. Resetting these reactive cell
Externí odkaz:
https://doaj.org/article/9721d7f26b7b4036901bb4feac886942
Autor:
Thomas Uray, Cameron Dezfulian, Abigail A. Palmer, Kristin M. Miner, Rehana K. Leak, Jason P. Stezoski, Keri Janesko‐Feldman, Patrick M. Kochanek, Tomas Drabek
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 10, Iss 5 (2021)
Background Current postresuscitative care after cardiac arrest (CA) does not address the cause of CA. We previously reported that asphyxial CA (ACA) and ventricular fibrillation CA (VFCA) elicit unique injury signatures. We hypothesized that the earl
Externí odkaz:
https://doaj.org/article/d62d95d93cc243bfa7def83aa2a0f282
Autor:
Xiaoming Hu, Kristin M. Miner, Rehana K. Leak, Tarun N. Bhatia, Jeffrey L. Brodsky, Anuj S Jamenis, Patrick G. Needham, Nevil Abraham, Kelvin C. Luk, Rachel N Clark, Elizabeth A. Eckhoff, Peter Wipf
Publikováno v:
Neurotherapeutics
The role of molecular chaperones, such as heat shock protein 70 (Hsp70), is not typically studied as a function of biological sex, but by addressing this gap we might improve our understanding of proteinopathic disorders that predominate in one sex.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::41e9fd8ee9bbce12d2879e678ce9ced8
https://doi.org/10.1007/s13311-021-01114-6
https://doi.org/10.1007/s13311-021-01114-6
Autor:
Anuj S. Jamenis, Tarun N. Bhatia, Kristin M. Miner, Krishna Kaku, Yesha Shah, Brett A. DeMarco, Rachel N. Clark, Aleem Gangjee, Rehana K. Leak
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::01af0040c0c16982a3be53006a2621c3
https://doi.org/10.1096/fasebj.2022.36.s1.r3222
https://doi.org/10.1096/fasebj.2022.36.s1.r3222
Autor:
Kristin M. Miner, Tarun N. Bhatia, Anuj S. Jamenis, Rachel N. Clark, Nevil Abraham, Dhivyaa Rajasundaram, Sylvie Sauvaigo, R. A. Stetler, Jun Chen, Laurie H. Sanders, Kelvin C. Luk, Rehana K. Leak
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96c126e9832bfd61425d1f3a2a9f08c2
https://doi.org/10.1096/fasebj.2022.36.s1.r3221
https://doi.org/10.1096/fasebj.2022.36.s1.r3221
Autor:
Kristin M. Miner, Anuj S. Jamenis, Tarun N. Bhatia, Rachel N. Clark, Dhivyaa Rajasundaram, Sylvie Sauvaigo, Daniel M. Mason, Jessica M. Posimo, Nevil Abraham, Brett A. DeMarco, Xiaoming Hu, R. Anne Stetler, Jun Chen, Laurie H. Sanders, Kelvin C. Luk, Rehana K. Leak
Publikováno v:
Progress in neurobiology. 216
Lewy body disorders are characterized by oxidative damage to DNA and inclusions rich in aggregated forms of α-synuclein. Among other roles, apurinic/apyrimidinic endonuclease 1 (APE1) repairs oxidative DNA damage, and APE1 polymorphisms have been li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::354701835fd5f9b1d1b4c76692864fa6
https://pubmed.ncbi.nlm.nih.gov/35710046
https://pubmed.ncbi.nlm.nih.gov/35710046
Autor:
Rehana K. Leak, John F. Stolz, Kristin M. Miner, Kelvin C. Luk, Daniel M. Mason, Yaqin Wang, Sara A. Trbojevic, Tarun N. Bhatia
Publikováno v:
Brain Pathol
At early disease stages, Lewy body disorders are characterized by limbic vs. brainstem α-synucleinopathy, but most preclinical studies have focused solely on the nigrostriatal pathway. Furthermore, male gender and advanced age are two major risk fac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4c7da766c4dc783be3ed67779edbfa4
https://doi.org/10.1111/bpa.12718
https://doi.org/10.1111/bpa.12718
Autor:
Rehana K. Leak, Cameron Dezfulian, Kristin M. Miner, Keri Janesko-Feldman, Thomas Uray, Jason Stezoski, Tomas Drabek, Abigail A. Palmer, Patrick M. Kochanek
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Current postresuscitative care after cardiac arrest (CA) does not address the cause of CA. We previously reported that asphyxial CA (ACA) and ventricular fibrillation CA (VFCA) elicit unique injury signatures. We hypothesized that the earl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9184b6d71c4bdefd2742ac6be3a7a34f
https://doi.org/10.1161/jaha.120.018657
https://doi.org/10.1161/jaha.120.018657
Autor:
David A. Johnson, Dishaben Soni, Rehana K. Leak, Kristin M. Miner, Benjamin K. Dumm, Tarun N. Bhatia, Negin Nouraei, Kelvin C. Luk, Daniel M. Mason, Michael A. Carcella
Publikováno v:
Experimental Neurology. 299:172-196
Lewy body disorders are characterized by the emergence of α-synucleinopathy in many parts of the central and peripheral nervous systems, including in the telencephalon. Dense α-synuclein+ pathology appears in regio inferior of the hippocampus in bo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7006368a9a9555e4adc7817c9360cbaa
https://doi.org/10.1016/j.expneurol.2017.10.017
https://doi.org/10.1016/j.expneurol.2017.10.017
Autor:
Kristin M. Miner, Daniel F. Hutchison, Negin Nouraei, Deepti B. Pant, Rehana K. Leak, Tarun N. Bhatia, Michael A. Carcella, Justin N. Weilnau
Publikováno v:
Brain Structure and Function. 223:1255-1273
Dopamine loss and motor deficits in Parkinson's disease typically commence unilaterally and remain asymmetric for many years, raising the possibility that endogenous defenses slow the cross-hemispheric transmission of pathology. It is well-establishe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae1060ce4c05c55d073ba7c252d07a3c
https://doi.org/10.1007/s00429-017-1552-6
https://doi.org/10.1007/s00429-017-1552-6