Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Kristin M. Mignogna"'
Publikováno v:
PLoS ONE, Vol 14, Iss 4, p e0202063 (2019)
Genome-wide association studies on alcohol dependence, by themselves, have yet to account for the estimated heritability of the disorder and provide incomplete mechanistic understanding of this complex trait. Integrating brain ethanol-responsive gene
Externí odkaz:
https://doaj.org/article/0ea67ab44f044813ac8eab92e14b6e8f
Autor:
Maren L. Smith, Kristin M. Mignogna, Jo L. Rokita, Lorna MacLeod, M. Imad Damaj, Michael F. Miles
Publikováno v:
Genes, Brain and Behavior. 22
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::61d0beb38d5f5cc730ddede639ba649c
https://doi.org/10.1111/gbb.12844
https://doi.org/10.1111/gbb.12844
Autor:
Zachary Tatom, Kristin M. Mignogna, Zachary Sergi, Jeremy Nguyen, Marie Michenkova, Maren L. Smith, Michael F. Miles
Traditional genetic mapping studies using inbred crosses are a powerful tool for identifying chromosomal regions associated with ethanol-related traits, but typically have very large confidence intervals which make identification of specific and pote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d2947bce9e27b2f8f304574fee5fd7f9
https://doi.org/10.1101/2022.12.06.519344
https://doi.org/10.1101/2022.12.06.519344
Autor:
Kristin M. Mignogna, Fernando S. Goes
Publikováno v:
Psychological medicine.
Background The course of Bipolar Disorder (BD) is highly variable, with marked inter and intra-individual differences in symptoms and functioning. In this study, we identified illness trajectories across major clinical domains that could have etiolog
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2246219799b4cc24eee5ab93a61c0c69
https://pubmed.ncbi.nlm.nih.gov/35699120
https://pubmed.ncbi.nlm.nih.gov/35699120
Autor:
Sean P. Farris, Michael F. Miles, Shizhong Han, Arpana Agrawal, Kristin M. Mignogna, Jessica E. Salvatore
Publikováno v:
Addiction Biology. 24:275-289
Alcohol use disorder (AUD) is a heritable complex behavior. Due to the highly polygenic nature of AUD, identifying genetic variants that comprise this heritable variation has proved to be challenging. With the exception of functional variants in alco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::96dae706bc0333000eb9d65bad064233
https://doi.org/10.1111/adb.12591
https://doi.org/10.1111/adb.12591
Publikováno v:
European Neuropsychopharmacology. 29:S880-S881
Background Despite studies suggesting that Alcohol Dependence (AD) is moderately heritable, Genome-Wide Association Studies (GWAS) on AD lack power for detecting the small contribution of individual genes to risk, and the ability to determine their m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a804fd9e19a45b6f668e940ef3bb998
https://doi.org/10.1016/j.euroneuro.2017.08.181
https://doi.org/10.1016/j.euroneuro.2017.08.181
Publikováno v:
Methods in Molecular Biology ISBN: 9781493964253
Complex behavioral traits, such as alcohol abuse, are caused by an interplay of genetic and environmental factors, producing deleterious functional adaptations in the central nervous system. The long-term behavioral consequences of such changes are o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3954ad2b81706ebb8e178551567872e2
https://doi.org/10.1007/978-1-4939-6427-7_26
https://doi.org/10.1007/978-1-4939-6427-7_26
Publikováno v:
PLoS ONE
PLoS ONE, Vol 14, Iss 4, p e0202063 (2019)
PLoS ONE, Vol 14, Iss 4, p e0202063 (2019)
Genome-wide association studies on alcohol dependence, by themselves, have yet to account for the estimated heritability of the disorder and provide incomplete mechanistic understanding of this complex trait. Integrating brain ethanol-responsive gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae3554569e0b32138e518e5a3bf3f72c
https://doi.org/10.1371/journal.pone.0202063
https://doi.org/10.1371/journal.pone.0202063