Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Kristin M. McCabe"'
Autor:
Kristin M. McCabe, Joanne Hsieh, David G. Thomas, Matthew M. Molusky, Liana Tascau, Jun B. Feranil, Li Qiang, Anthony W. Ferrante, Jr., Alan R. Tall
Publikováno v:
Molecular Metabolism, Vol 34, Iss , Pp 146-156 (2020)
Objective: In mouse models, deficiency of TTC39B (T39) decreases hepatic lipogenic gene expression and protects against diet-induced steatohepatitis. While assessing the therapeutic potential of antisense oligonucleotides (ASOs) targeting T39, we dis
Externí odkaz:
https://doaj.org/article/04e06894453b43d483a10eb29623aa72
Publikováno v:
Nutrients, Vol 5, Iss 11, Pp 4390-4398 (2013)
The purpose of this review is to summarize the research to date on vitamin K status in chronic kidney disease (CKD). This review includes a summary of the data available on vitamin K status in patients across the spectrum of CKD as well as the link b
Externí odkaz:
https://doaj.org/article/6d3bf4dd34824e45ad2088035475e85f
Autor:
Liana Tascau, Joanne Hsieh, Tong Xiao, Alan R. Tall, Matthew M. Molusky, Lars Zeana-Schliep, Panagiotis Fotakis, Paul DaSilva-Jardine, Kristin M. McCabe
Publikováno v:
J Hepatol
Background/Aims Molecular mechanisms underlying the different susceptibility of men and women to NAFLD are poorly understood. The TTC39B locus encodes a scaffolding protein, associates with gynecological disorders and its deletion protects mice from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b5be3f8afcd8ed7a16596e488d61d0c
https://doi.org/10.1016/j.jhep.2021.09.021
https://doi.org/10.1016/j.jhep.2021.09.021
Autor:
Anthony W. Ferrante, Matthew M. Molusky, David G. Thomas, Liana Tascau, Kristin M. McCabe, Alan R. Tall, Li Qiang, Joanne Hsieh, Jun B. Feranil
Publikováno v:
Molecular Metabolism
Molecular Metabolism, Vol 34, Iss, Pp 146-156 (2020)
Molecular Metabolism, Vol 34, Iss, Pp 146-156 (2020)
Objective In mouse models, deficiency of TTC39B (T39) decreases hepatic lipogenic gene expression and protects against diet-induced steatohepatitis. While assessing the therapeutic potential of antisense oligonucleotides (ASOs) targeting T39, we disc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9033910c2145afa4d053540659ac5a00
https://doi.org/10.1016/j.molmet.2020.01.010
https://doi.org/10.1016/j.molmet.2020.01.010
Autor:
Henry Barron, Michael A. Adams, Emilie Ward, Glenville Jones, Kimberly Laverty, Jason G.E. Zelt, Martin Kaufmann, Kristin M. McCabe, Rachel M. Holden
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 366:433-445
Patients with chronic kidney disease (CKD) have a markedly increased risk for developing cardiovascular disease. Nontraditional risk factors, such as increased phosphate retention, increased serum fibroblast growth factor 23 (FGF-23), and deficiencie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b8ba48fdaace15eee7f1d59c7840125
https://doi.org/10.1124/jpet.117.247270
https://doi.org/10.1124/jpet.117.247270
Publikováno v:
Nutrients
Nutrients, Vol 5, Iss 11, Pp 4390-4398 (2013)
Nutrients, Vol 5, Iss 11, Pp 4390-4398 (2013)
The purpose of this review is to summarize the research to date on vitamin K status in chronic kidney disease (CKD). This review includes a summary of the data available on vitamin K status in patients across the spectrum of CKD as well as the link b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e8b1f2b879070565ca5cb3e4dbe7f9db
http://europepmc.org/articles/PMC3847737
http://europepmc.org/articles/PMC3847737
Autor:
Xueyan Fu, Navid Shobeiri, Kristin M. McCabe, Rachel M. Holden, Michael A. Adams, Sarah L. Booth, Judith J. Pang
Publikováno v:
Kidney International. 83:835-844
The leading cause of death in patients with chronic kidney disease (CKD) is cardiovascular disease, with vascular calcification being a key modifier of disease progression. A local regulator of vascular calcification is vitamin K. This γ-glutamyl ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90ea32f8d32aad46983d1630b9bd74cd
https://doi.org/10.1038/ki.2012.477
https://doi.org/10.1038/ki.2012.477
Autor:
Kristin M. McCabe, Rachel M. Holden, Xueyan Fu, Michael A. Adams, Sarah L. Booth, Emilie Ward
Publikováno v:
American journal of nephrology. 45(1)
Background: Patients with chronic kidney disease (CKD) have very high levels of uncarboxylated, inactive, extra-hepatic vitamin K-dependent proteins measured in circulation, putting them at risk for complications of vitamin K deficiency. The major fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46bbe4093b41f561504b99c1e057c412
https://pubmed.ncbi.nlm.nih.gov/27846632
https://pubmed.ncbi.nlm.nih.gov/27846632
Autor:
Michael A. Adams, Bruno Svajger, Kim Laverty, Jason G.E. Zelt, Henry Barron, Kristin M. McCabe, Rachel M. Holden
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 355(3)
Chronic kidney disease (CKD) patients are commonly treated with vitamin D analogs, such as calcitriol. Recent epidemiologic evidence revealed a significant interaction between vitamin D and magnesium, since an inverse relationship between vitamin D l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be4a62ae8a95b37f058c88aeda75625f
https://pubmed.ncbi.nlm.nih.gov/26487689
https://pubmed.ncbi.nlm.nih.gov/26487689
Autor:
Louise Moist, M. Kyla Shea, Sheldon W. Tobe, Kristin M. McCabe, Deborah Zimmerman, Daren K. Heyland, Sarah L. Booth, Catherine M. Clase, Rachel M. Holden, Michael A. Adams, Jordan Weinstein, Rao Madhumathi, Sophie A. Jamal, Andrew G. Day
Publikováno v:
Canadian Journal of Kidney Health and Disease
Canadian Journal of Kidney Health and Disease, Vol 2 (2015)
Canadian Journal of Kidney Health and Disease, Vol 2 (2015)
Cardiovascular disease, which is due in part to progressive vascular calcification, is the leading cause of death among patients with end stage kidney disease (ESKD) on dialysis. A role for vitamin K in the prevention of vascular calcification is pla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee98bbfa9841334c0ead7f71f174c207
http://europepmc.org/articles/PMC4465015
http://europepmc.org/articles/PMC4465015