Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Kristin M. Engebretsen"'
Publikováno v:
Indian J Hematol Blood Transfus
Dabigatran etexilate is an oral direct thrombin (Factor IIa) inhibitor approved for patients with atrial fibrillation and for management of risk of deep vein thrombosis and pulmonary embolism. Dabigatran offers advantages over treatment with warfarin
Autor:
Sean P Boley, Jenna M. Leroy, Kristin M. Engebretsen, Samuel J. Stellpflug, Rebecca B. Mackenzie
Publikováno v:
J Med Toxicol
INTRODUCTION: Toxicity related to calcium-channel blockers remains a significant cause of morbidity and mortality. Amlodipine-induced shock is unique in that its mechanism of action is thought to occur in part via the release of nitric oxide (NO) in
Autor:
Kristin M. Engebretsen, Katherine G. Katzung, Samuel J. Stellpflug, Jenna M. Leroy, Sean P Boley, Joel S. Holger
Publikováno v:
Clinical Toxicology. 57:1073-1079
Context: Although cerebral perfusion (CP) is preserved across a wide range of mean arterial pressures (MAP) through cerebral-vascular autoregulation, the relationship between MAP and CP in refracto...
Publikováno v:
J Med Toxicol
INTRODUCTION: Vasopressors are a commonly used treatment in beta-blocker poisoning despite evidence they may be ineffective or harmful. The primary objective of the present study is to use previously collected data from two prior studies (high-dose i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ace1e2ed4389d03abbfaf20e8977b167
https://europepmc.org/articles/PMC7099112/
https://europepmc.org/articles/PMC7099112/
Autor:
Kristin M. Engebretsen, Sean P Boley, Samuel J. Stellpflug, Jenna M. Leroy, Justin N Corcoran
Publikováno v:
J Med Toxicol
INTRODUCTION: Calcium channel blocker (CCB) overdoses cause significant morbidity and mortality. Dihydropyridine CCBs cause peripheral vascular dilation and at high doses cardiac dysfunction. Amlodipine, a dihydropyridine, causes peripheral vasodilat
Publikováno v:
Clinical Toxicology. 55:285-304
Overdoses with cardio-depressive medications can result in toxin-induced cardiogenic shock (TICS), a life-threatening condition characterized by severe hypotension and ineffective tissue perfusion. Vasopressors are often employed in the treatment of
Publikováno v:
J Med Toxicol
INTRODUCTION: High-dose insulin (HDI) therapy has been used successfully for beta-blocker toxicity, but needs further study when hypotension persists despite HDI. The objective was to develop a model of propranolol toxicity with persistent hypotensio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1d4d8b267534940282300fafd28a5e7
https://europepmc.org/articles/PMC6597671/
https://europepmc.org/articles/PMC6597671/
Autor:
Jon B. Cole, Kristin M. Engebretsen, Alex O’Brien-Lambert, Johanna C. Moore, Lila W. Steinberg, Paul C. Nystrom, Brandon J. Fryza, Jeffrey D. Ho, Rebecca L. Kornas, Benjamin S. Orozco, Samuel J. Stellpflug, Peter Bache-Wiig
Publikováno v:
Clinical Toxicology. 54:556-562
Ketamine is an emerging drug for the treatment of acute undifferentiated agitation in the prehospital environment, however no prospective comparative studies have evaluated its effectiveness or safety in this clinical setting.We hypothesized 5 mg/kg
Autor:
Eric V. Ernest, Bjorn K. Peterson, Aaron M. Burnett, Dolly Panchal, Kristin M. Engebretsen, Kent R. Griffith, Ralph J. Frascone
Publikováno v:
Australasian Journal of Paramedicine. 12:1-7
Introduction Agitated patients who present a danger to themselves or emergency medical services (EMS) providers may require chemical restraints. Haloperidol is employed for chemical restraint in many EMS services. Recently, ketamine has been introduc
Publikováno v:
Journal of Medical Toxicology. 9:172-178
New groups of synthetic “designer drugs” have increased in popularity over the past several years. These products mimic the euphoric effects of other well-known illicit drugs but are advertised as “legal” highs and are sold over the internet,