Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Kristin M. Burkhart"'
Autor:
David K. Madtes, Kyoung Hee Kim, Paul D. Soloway, Robert C. Hackman, Charles W. Frevert, Kristin M. Burkhart, Julie Randolph-Habecker, Peter Chen
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 33:271-279
Bleomycin-induced lung injury triggers a profound and durable increase in tissue inhibitor of metalloproteinase (TIMP)-1 expression, suggesting a potential role for this antiproteinase in the regulation of lung inflammation and fibrosis. TIMP-1 prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eee50ab57369ad7aa97e06b4bfffb04e
https://doi.org/10.1165/rcmb.2005-0111oc
https://doi.org/10.1165/rcmb.2005-0111oc
Autor:
Joan G. Clark, David K. Madtes, John M. Harlan, Anne E. Dixon, Kristin M. Burkhart, Janis B. Mandac-Dy, Daniel C. Bullard
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology. 30:220-227
Trafficking of lymphocytes to lung is a critical component of pulmonary immune defense and surveillance. Selectins, expressed on vascular endothelium, regulate T lymphocyte emigration into tissues, such as skin, but the role of the selectins in traff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::252975bfcb35525bbdad3657f6cafa08
https://doi.org/10.1165/rcmb.2003-0208oc
https://doi.org/10.1165/rcmb.2003-0208oc
Publikováno v:
Kidney International. 56:1788-1797
Increased proximal tubular cholesterol content: Implications for cell injury and "acquired cytoresistance." Background Acute renal failure (ARF) leads to secondary adaptive changes that serve to protect proximal tubules from subsequent ischemic or to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35ccdc3eaeabd9507bf0153e7bc2ef6a
https://doi.org/10.1046/j.1523-1755.1999.00745.x
https://doi.org/10.1046/j.1523-1755.1999.00745.x
Publikováno v:
Kidney International. 56(1):104-117
Plasma membrane phospholipid integrity and orientation during hypoxic and toxic proximal tubular attack. Background Acute cell injury can activate intracellular phospholipase A 2 (PLA 2 ) and can inhibit plasma membrane aminophospholipid translocase(
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1b412dd8edef1fd1c0210689e2a3c9f
Publikováno v:
Kidney International. 55:148-159
Isoflurane alters proximal tubular cell susceptibility to toxic and hypoxic forms of attack. Background Fluorinated anesthetics can profoundly alter plasma membrane structure and function, potentially impacting cell injury responses. Because major su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::090ff6a2efe61089485cc60b4c99ba77
https://doi.org/10.1046/j.1523-1755.1999.00238.x
https://doi.org/10.1046/j.1523-1755.1999.00238.x
Publikováno v:
Kidney International. 52:60-70
Altered ceramide and sphingosine expression during the induction phase of ischemic acute renal failure. Recent evidence indicates that a "sphingomyelin signaling pathway" exists: in response to heterogeneous influences, sphingomyelin is hydrolyzed, l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df0253c17750095a5183406832de0348
https://doi.org/10.1038/ki.1997.304
https://doi.org/10.1038/ki.1997.304
Autor:
Richard A. Zager, Kristin M. Burkhart
Publikováno v:
Kidney International. 51:728-738
Myoglobin toxicity in proximal human kidney cells: Roles of Fe, Ca 2+ , H 2 O 2 , and terminal mitochondrial electron transport. The purpose of this study was to gain direct insights into mechanisms by which myoglobin induces proximal tubular cell de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::848874fc4927f5c32db9594a66790ce0
https://doi.org/10.1038/ki.1997.104
https://doi.org/10.1038/ki.1997.104
Publikováno v:
Journal of the American Society of Nephrology. 7:2327-2339
During the course of O2 deprivation-induced proximal tubular injury, profound alterations in ATP homeostasis exist. This study sought to characterize direct cellular determinants of these abnormalities further. Mouse proximal tubular segments (PTS) w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f7c26d8bf7b488e0b012c0f60b79262
https://doi.org/10.1681/asn.v7112327
https://doi.org/10.1681/asn.v7112327
Publikováno v:
Journal of the American Society of Nephrology. 7:64-72
Addition of phospholipase A2 (PLA2) to isolated proximal tubular segments (PTS) has previously been shown to decrease hypoxic cell death without altering ATP concentrations. The study presented here was undertaken to identify determinant(s) of this p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a2ef21b8b195f68d28d758cd4a45b0b
https://doi.org/10.1681/asn.v7164
https://doi.org/10.1681/asn.v7164
Autor:
Richard A. Zager, Kristin M. Burkhart
Publikováno v:
Kidney international. 53(6)
Differential effects of glutathione and cysteine on Fe 2+ , Fe 3+ , H 2 O 2 and myoglobulin-induced proximal tubular cell attack. Glutathione (GSH) is widely advocated as a cytoprotectant for preventing oxidant forms of renal damage. However, in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd34c0987b537fd382818591c846386a
https://pubmed.ncbi.nlm.nih.gov/9607198
https://pubmed.ncbi.nlm.nih.gov/9607198