Zobrazeno 1 - 10
of 25
pro vyhledávání: '"Kristin M. Bircsak"'
Autor:
Camilla Soragni, Gwenaëlle Rabussier, Henriëtte L. Lanz, Kristin M. Bircsak, Leon J. de Windt, Sebastiaan J. Trietsch, Colin E. Murdoch, Chee Ping Ng
Publikováno v:
Redox Biology, Vol 57, Iss , Pp 102488- (2022)
Reactive oxygen species (ROS) have different properties and biological functions. They contribute to cell signaling and, in excessive amounts, to oxidative stress (OS). Although ROS is pivotal in a wide number of physiological systems and pathophysio
Externí odkaz:
https://doaj.org/article/857f974442214bc5869b76984b57a033
Autor:
Gwenaëlle Rabussier, Ivan Bünter, Josse Bouwhuis, Camilla Soragni, Torben van Zijp, Chee Ping Ng, Karel Domansky, Leon J. de Windt, Paul Vulto, Colin E. Murdoch, Kristin M. Bircsak, Henriëtte L. Lanz
Publikováno v:
Acta Biomaterialia. 164:363-376
Autor:
Lindsey K. Sablatura, Kristin M. Bircsak, Peter Shepherd, Madhavi Bathina, Karla Queiroz, Mary C. Farach‐Carson, Rick A. Kittles, Pamela E. Constantinou, Anthony Saleh, Nora M. Navone, Daniel A. Harrington
Publikováno v:
Advanced healthcare materials.
Many advanced cancer models, such as patient-derived xenografts (PDXs), offer significant benefits in their preservation of the native tumor's heterogeneity and susceptibility to treatments, but face significant barriers to use in their reliance on a
Autor:
Jianyao Du, Anna M. Vetrano, Kristin M. Bircsak, Lauren M. Aleksunes, Ludwik Gorczyca, Xia Wen
Publikováno v:
FEBS Lett
Low oxygen concentration, or hypoxia, is an important physiological regulator of placental function including chemical disposition. Here, we compared the ability of low oxygen tension to alter the expression of solute carriers (SLC) and ABC transport
Autor:
Sara King, George L. Gerton, Andrew M. Prantner, Kristin M. Bircsak, Wei-Ting Hwang, Latresa T. Copes
Publikováno v:
Reprod Toxicol
Many reports describe an association between preconceptional paternal exposure to environmental chemicals, including the persistent organic pollutant 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) with an increased number of female offspring. We chronica
Autor:
Pamela E. Constantinou, Lindsey K. Sablatura, Peter Shepherd, Anthony Saleh, Kristin M. Bircsak, Nora M. Navone, Mary C. Farach-Carson, Karla Queiroz, Daniel A. Harrington
Publikováno v:
J Vis Exp
Patient-derived xenografts (PDX), generated when resected patient tumor tissue is engrafted directly into immunocompromised mice, remain biologically stable, thereby preserving molecular, genetic, and histological features, as well as heterogeneity o
Autor:
Daniel A. Harrington, Nora Navone, Anthony Saleh, Pamela E. Constantinou, Mary C. Farach-Carson, Karla Queiroz, Peter Shepherd, Kristin M. Bircsak, Lindsey K. Sablatura
Publikováno v:
Journal of Visualized Experiments.
Autor:
Mark T. Miedel, Anthony Saleh, Lawrence Vernetti, Richard DeBiasio, Alaa Alsebahi, Kristin M. Bircsak, Ryan Reddinger, Albert Gough, Tongying Shun
Publikováno v:
Toxicology. 450
We report the development, automation and validation of a 3D, microfluidic liver-on-a-chip for high throughput hepatotoxicity screening, the OrganoPlate LiverTox™. The model is comprised of aggregates of induced pluripotent stem cell (iPSC)-derived
Autor:
Barry Weinberger, Laura Saba, Poi Yu Sofia Yuen, Lauren M. Aleksunes, Jamie E. Moscovitz, Naureen Memon, Xia Wen, Kristin M. Bircsak, Faith E. Archer, Anna M. Vetrano, Moiz Mohammed
Publikováno v:
Drug Metabolism and Disposition. 46:619-627
The breast cancer resistance protein (BCRP/ABCG2) is a maternally-facing efflux transporter that regulates the placental disposition of chemicals. Transcription factors and gene variants are important regulatory factors that influence transporter exp
Autor:
Chee Ng, Henriëtte L. Lanz, Leon J. De Windt, Gwenaëlle Rabussier, Kristin M. Bircsak, Camilla Soragni
Publikováno v:
Placenta. 112:e64