Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Kristin Ludwig"'
Autor:
Cynthia Weigel, Sören S. Hüttner, Kristin Ludwig, Nadine Krieg, Susann Hofmann, Nathalie H. Schröder, Linda Robbe, Stefan Kluge, Axel Nierhaus, Martin S. Winkler, Ignacio Rubio, Julia von Maltzahn, Sarah Spiegel, Markus H. Gräler
Publikováno v:
EBioMedicine, Vol 58, Iss , Pp 102898- (2020)
Background: One-third of all deaths in hospitals are caused by sepsis. Despite its demonstrated prevalence and high case fatality rate, antibiotics remain the only target-oriented treatment option currently available. Starting from results showing th
Externí odkaz:
https://doaj.org/article/9808a6a5b10f4517b6cf8ea63bf022e8
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Endotoxin tolerance represents a safeguard mechanism for preventing detrimental prolonged inflammation and exaggerated immune/inflammatory responses from innate immune cells to recurrent harmless pathogens. On the other hand, excessive immune toleran
Externí odkaz:
https://doaj.org/article/12d67611e59d47118d65c4fe2083d0f4
Autor:
Lareno L. Villones, Anna-Kristin Ludwig, Hiroyuki Kumeta, Seiya Kikuchi, Rika Ochi, Tomoyasu Aizawa, Shin-Ichiro Nishimura, Hans-Joachim Gabius, Hiroshi Hinou
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-16 (2022)
Abstract Dystroglycan (DG), which constitutes a part of the dystrophin–glycoprotein complex, connects the extracellular matrix to the cytoskeleton. The matriglycans presented by the extracellular α-DG serve as a contact point with extracellular ma
Externí odkaz:
https://doaj.org/article/3b313ae12f4c4ebbae078d91bb584ce4
Autor:
Paul V. Murphy, Antonio Romero, Qi Xiao, Anna-Kristin Ludwig, Srinivas Jogula, Nadezhda V. Shilova, Tanuja Singh, Adele Gabba, Bilal Javed, Dapeng Zhang, Francisco J. Medrano, Herbert Kaltner, Jürgen Kopitz, Nicolai V. Bovin, Albert M. Wu, Michael L. Klein, Virgil Percec, Hans-Joachim Gabius
Publikováno v:
iScience, Vol 24, Iss 1, Pp 101919- (2021)
Summary: The small 3-O-sulfated galactose head group of sulfatides, an abundant glycosphingolipid class, poses the (sphinx-like) riddle on involvement of glycan bridging by tissue lectins (sugar code). First, synthesis of head group derivatives for f
Externí odkaz:
https://doaj.org/article/a0046aeb444a470d8b22c9dce74afb36
Autor:
Federico M. Ruiz, Francisco J. Medrano, Anna-Kristin Ludwig, Herbert Kaltner, Nadezhda V. Shilova, Nicolai V. Bovin, Hans-Joachim Gabius, Antonio Romero
Publikováno v:
Biomolecules, Vol 11, Iss 12, p 1854 (2021)
Galectins are multi-purpose effectors acting via interactions with distinct counterreceptors based on protein-glycan/protein recognition. These processes are emerging to involve several regions on the protein so that the availability of a detailed st
Externí odkaz:
https://doaj.org/article/29179773c8434d8f8b374cf9022f9da3
Autor:
Anna-Kristin Ludwig, Kyra De Miroschedji, Thorsten R. Doeppner, Verena Börger, Johannes Ruesing, Vera Rebmann, Stephan Durst, Sören Jansen, Michel Bremer, Elmar Behrmann, Bernhard B. Singer, Holger Jastrow, Jan Dominik Kuhlmann, Fouzi El Magraoui, Helmut E. Meyer, Dirk M. Hermann, Bertram Opalka, Stefan Raunser, Matthias Epple, Peter A. Horn, Bernd Giebel
Publikováno v:
Journal of Extracellular Vesicles, Vol 7, Iss 1 (2018)
Extracellular vesicles (EVs) provide a complex means of intercellular signalling between cells at local and distant sites, both within and between different organs. According to their cell-type specific signatures, EVs can function as a novel class o
Externí odkaz:
https://doaj.org/article/818ba5492eb54a3a8ed20c14c4c09196
Autor:
Lareno L. Villones, Anna‐Kristin Ludwig, Seiya Kikuchi, Rika Ochi, Shin‐Ichiro Nishimura, Hans‐Joachim Gabius, Herbert Kaltner, Hiroshi Hinou
Publikováno v:
ChemBioChem.
Autor:
Daan R.M.G. Ophelders, Tim G.A.M. Wolfs, Reint K. Jellema, Alex Zwanenburg, Peter Andriessen, Tammo Delhaas, Anna-Kristin Ludwig, Stefan Radtke, Vera Peters, Leon Janssen, Bernd Giebel, Boris W. Kramer
Publikováno v:
Stem Cells Translational Medicine, Vol 5, Iss 6, Pp 754-763 (2016)
Preterm neonates are susceptible to perinatal hypoxic‐ischemic brain injury, for which no treatment is available. In a preclinical animal model of hypoxic‐ischemic brain injury in ovine fetuses, we have demonstrated the neuroprotective potential
Externí odkaz:
https://doaj.org/article/29030b3ea97e4a9a974183f7346a8ae7
Autor:
Andreas Schedlbauer, Herbert Kaltner, Hans-Joachim Gabius, Kevin H. Mayo, Ingo Lindner, Tammo Diercks, Anna Kristin Ludwig, Andreas Adler, Ulrich Gilles, Dietmar Reusch
Publikováno v:
Biochimie. 187:48-56
Glycans of cellular glycoconjugates serve as biochemical signals for a multitude of (patho)physiological processes via binding to their receptors (e.g. lectins). In the case of human adhesion/growth-regulatory galectin-1 (Gal-1), small angle neutron
Autor:
Gabriel García Caballero, Herbert Kaltner, Joachim C. Manning, Hans-Joachim Gabius, Alonso M. Higuero, José Abad-Rodríguez, Felix A. Habermann, Anna-Kristin Ludwig
Publikováno v:
Acta Histochemica et Cytochemica
As letters form the vocabulary of a language, biochemical 'symbols' (the building blocks of oligo- and polymers) make writing molecular messages possible. Compared to nucleotides and amino acids, sugars have chemical properties that facilitate to rea