Alteration of blood monocyte subsets in chronic rhinosinusitis with regard to anti-inflammatory 1,8-Cineol treatment

Autor: Christina Polasky, Kristin Loyal, Christian Idel, David Wetterauer, Mathias Heidemann, Karl-Ludwig Bruchhage, Ralph Pries

Publikováno v: Rhinology Online, Vol 4, Iss 4, Pp 194-202 (2021)

Background: Chronic rhinosinusitis (CRS) affects about 10% of the european population causing considerable disease burden. The inflammatory microenvironment is mainly Th2 driven, but the impact of monocytes is still poorly understood. Aim of this stu

Externí odkaz: https://doaj.org/article/930a2e9359d148659330ed493409be87

Impact of Superparamagnetic Iron Oxide Nanoparticles on THP-1 Monocytes and Monocyte-Derived Macrophages

Autor: Christina Polasky, Tim Studt, Ann-Kathrin Steuer, Kristin Loyal, Kerstin Lüdtke-Buzug, Karl-Ludwig Bruchhage, Ralph Pries

Publikováno v: Frontiers in Molecular Biosciences, Vol 9 (2022)

Superparamagnetic iron oxide nanoparticles (SPIONs) are currently under examination for magnetic particle imaging, which represents a radiation free technology for three-dimensional imaging with high sensitivity, resolution and imaging speed. SPIONs

Externí odkaz: https://doaj.org/article/dfc8ed5b09e04dddbd7781c173ab8184

Smoking-, Alcohol-, and Age-Related Alterations of Blood Monocyte Subsets and Circulating CD4/CD8 T Cells in Head and Neck Cancer

Autor: Christian Idel, Kristin Loyal, Dirk Rades, Samer G. Hakim, Udo Schumacher, Karl-Ludwig Bruchhage, Ralph Pries

Publikováno v: Biology, Vol 11, Iss 5, p 658 (2022)

Head and neck squamous cell carcinoma (HNSCC) represents a heterogeneous malignant disease of the oral cavity, pharynx, and larynx. Although cigarette smoking, alcohol abuse, and aging are well-established associated factors for HNSCC, their respecti

Externí odkaz: https://doaj.org/article/520c78b04dee4fa89849cb442d38993e

Redistribution of Monocyte Subsets in Obstructive Sleep Apnea Syndrome Patients Leads to an Imbalanced PD-1/PD-L1 Cross-Talk with CD4/CD8 T Cells

Autor: Kristin Loyal, Armin Steffen, Ralph Pries, Christina Polasky, Karl-Ludwig Bruchhage, Christian M. Lange

Publikováno v: The Journal of Immunology. 206:51-58

Obstructive sleep apnea syndrome (OSAS) represents a substantial disease of recurrent sleep fragmentation, leading to intermittent hypoxia and subsequent diseases such as cardiovascular, metabolic, or cognitive dysfunctions. In addition, OSAS is cons

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc170ef2f4255543b3258833eabe3320
https://doi.org/10.4049/jimmunol.2001047

Reconstitution of Monocyte Subsets and PD-L1 Expression but Not T Cell PD-1 Expression in Obstructive Sleep Apnea Patients upon PAP Therapy

Autor: Armin Steffen, Christian Lange, Karl-Ludwig Bruchhage, Christina Polasky, Ralph Pries, Kristin Loyal

Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 11375, p 11375 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 21

Obstructive sleep apnea (OSA) is characterized by nocturnal breathing intermissions resulting in oxidative stress and eventually, a low-grade systemic inflammation. The study aimed to investigate the impact of positive airway pressure (PAP) therapy o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7a72ba50fc28a47409d9b91ba11380a
https://www.mdpi.com/1422-0067/22/21/11375