Výsledky vyhledávání - "Kristin L. Abel"

Administration of recombinant FVIIa (rFVIIa) to concizumab-dosed monkeys is safe, and concizumab does not affect the potency of rFVIIa in hemophilic rabbits

Autor: Kristoffer W. Balling, Brian Lauritzen, Janne Olling, Mads Bjelke, Cecilia Augustsson, Ida Hilden, Anne Charlotte Hegelund, Kristin L. Abel

Publikováno v: Journal of thrombosis and haemostasis : JTH. 17(3)

Essentials Hemophilia patients on concizumab prophylaxis may need rFVIIa to treat breakthrough bleeds. Effect and safety of concizumab + rFVIIa were tested in vitro and in vivo. Concizumab + rFVIIa had no additive effects on bleeding in hemophilic ra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::528632585c3f57299874fefbf22845cf
https://pubmed.ncbi.nlm.nih.gov/30614620

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Design of 5′ Untranslated Sequences in Retroviral Vectors Developed for Medical Use

Autor: Markus Hildinger, Wolfram Ostertag, Kristin L. Abel, Christopher Baum

Publikováno v: Journal of Virology. 73:4083-4089

Utilizing genetic modules of simple retroviruses, we have developed a novel generation of gene transfer vectors with improved therapeutic potential. In the 5′ untranslated “leader” sequences, all AUG codons which may aberrantly initiate transla

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c01f15ca7333c542bea3e4335c0b7897
https://doi.org/10.1128/jvi.73.5.4083-4089.1999

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High-dose erythropoietin alters platelet reactivity and bleeding time in rodents in contrast to the neuroprotective variant carbamyl-erythropoietin (CEPO)

Autor: Louise Bochsen, Marcel Leist, Jens Gerwien, Lars Torup, Pär I. Johansson, Marianne Kjalke, Agnete Kirkeby, Kristin L. Abel, Kim Theilgaard-Mönch, Søren E. Bjørn

Publikováno v: University of Copenhagen

SummaryThe haematopoietic hormone erythropoietin (EPO) has neuroprotective properties and is currently being explored for treatment of stroke and other neurological disorders. Short-term, high-dose treatment with EPO seems to improve neurological fun

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90e65b8ecf5518a71acf3f2982c645fe
https://pubmed.ncbi.nlm.nih.gov/18392330

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