Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Kristin L Zuromski"'
Publikováno v:
eLife, Vol 9 (2020)
AAA+ proteases perform regulated protein degradation in all kingdoms of life and consist of a hexameric AAA+ unfoldase/translocase in complex with a self-compartmentalized peptidase. Based on asymmetric features of cryo-EM structures and a sequential
Externí odkaz:
https://doaj.org/article/a60053f5c3f7400988af78e101b7ab9c
Publikováno v:
The Journal of Biological Chemistry
ClpAP, an ATP-dependent protease consisting of ClpA, a double-ring hexameric unfoldase of the ATPases associated with diverse cellular activities superfamily, and the ClpP peptidase, degrades damaged and unneeded proteins to support cellular proteost
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::892c76a3e6a107ae1b9fb8e25cbed710
https://pubmed.ncbi.nlm.nih.gov/34780718
https://pubmed.ncbi.nlm.nih.gov/34780718
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Understanding of how ClpA and other double-ring AAA+ enzymes perform mechanical work is limited. Using site-specific cross-linking and mutagenesis, we introduced ATPase-inactive AAA+ modules at alternating positions in individual ClpA ri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::59b2347898256ca997195577b71c906d
https://pubmed.ncbi.nlm.nih.gov/33020301
https://pubmed.ncbi.nlm.nih.gov/33020301