Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Kristin L, McNally"'
Autor:
Gayatri Subramanian, Adam Hage, Friederike Feldmann, Abhilash I. Chiramel, Kristin L. McNally, Gail L. Sturdevant, Paul A. Beare, Sonja M. Best
Publikováno v:
Viruses, Vol 16, Iss 9, p 1377 (2024)
The unprecedented research effort associated with the emergence of severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) included several extensive proteomic studies that identified host proteins that interact with individual viral gene produc
Externí odkaz:
https://doaj.org/article/b6f86d9456e7430c99d8646e2ca3fe4f
Autor:
Shelly J. Robertson, Olivia Bedard, Kristin L. McNally, Carl Shaia, Chad S. Clancy, Matthew Lewis, Rebecca M. Broeckel, Abhilash I. Chiramel, Jeffrey G. Shannon, Gail L. Sturdevant, Rebecca Rosenke, Sarah L. Anzick, Elvira Forte, Christoph Preuss, Candice N. Baker, Jeffrey M. Harder, Catherine Brunton, Steven Munger, Daniel P. Bruno, Justin B. Lack, Jacqueline M. Leung, Amirhossein Shamsaddini, Paul Gardina, Daniel E. Sturdevant, Jian Sun, Craig Martens, Steven M. Holland, Nadia A. Rosenthal, Sonja M. Best
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Inflammation in response to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection drives severity of coronavirus disease 2019 (COVID-19) and is influenced by host genetics. To understand mechanisms of inflammation, animal mo
Externí odkaz:
https://doaj.org/article/4707d2cef54a462c9164528ec8d5861f
Autor:
Rebecca M Broeckel, Friederike Feldmann, Kristin L McNally, Abhilash I Chiramel, Gail L Sturdevant, Jacqueline M Leung, Patrick W Hanley, Jamie Lovaglio, Rebecca Rosenke, Dana P Scott, Greg Saturday, Fadila Bouamr, Angela L Rasmussen, Shelly J Robertson, Sonja M Best
Publikováno v:
PLoS Pathogens, Vol 17, Iss 12, p e1009678 (2021)
Kyasanur Forest disease virus (KFDV) and the closely related Alkhurma hemorrhagic disease virus (AHFV) are emerging flaviviruses that cause severe viral hemorrhagic fevers in humans. Increasing geographical expansion and case numbers, particularly of
Externí odkaz:
https://doaj.org/article/e75b0f0e8a774ab2b7bf41f32357fe43
Autor:
Brian H. Youseff, Thomas G. Brewer, Kristin L. McNally, Adaeze O. Izuogu, Kirk J. Lubick, John B. Presloid, Saad Alqahtani, Saurabh Chattopadhyay, Sonja M. Best, Xiche Hu, R. Travis Taylor
Publikováno v:
iScience, Vol 15, Iss , Pp 489-501 (2019)
Summary: Tick-borne flaviviruses (TBFVs) can cause life-threatening encephalitis and hemorrhagic fever. To identify virus-host interactions that may be exploited as therapeutic targets, we analyzed the TBFV polyprotein in silico for antiviral protein
Externí odkaz:
https://doaj.org/article/2689687ad01c41adb8ca44fe7f6df55a
Autor:
Abhilash I. Chiramel, Nicholas R. Meyerson, Kristin L. McNally, Rebecca M. Broeckel, Vanessa R. Montoya, Omayra Méndez-Solís, Shelly J. Robertson, Gail L. Sturdevant, Kirk J. Lubick, Vinod Nair, Brian H. Youseff, Robin M. Ireland, Catharine M. Bosio, Kyusik Kim, Jeremy Luban, Vanessa M. Hirsch, R. Travis Taylor, Fadila Bouamr, Sara L. Sawyer, Sonja M. Best
Publikováno v:
Cell Reports, Vol 27, Iss 11, Pp 3269-3283.e6 (2019)
Summary: Tripartite motif-containing protein 5α (TRIM5α) is a cellular antiviral restriction factor that prevents early events in retrovirus replication. The activity of TRIM5α is thought to be limited to retroviruses as a result of highly specifi
Externí odkaz:
https://doaj.org/article/680b7a0b93c5469cbbde7dcdbb3d4d2d
Autor:
Kevin M. Rose, Stephanie J. Spada, Rebecca Broeckel, Kristin L. McNally, Vanessa M. Hirsch, Sonja M. Best, Fadila Bouamr
Publikováno v:
Viruses, Vol 13, Iss 3, p 446 (2021)
An evolutionary arms race has been ongoing between retroviruses and their primate hosts for millions of years. Within the last century, a zoonotic transmission introduced the Human Immunodeficiency Virus (HIV-1), a retrovirus, to the human population
Externí odkaz:
https://doaj.org/article/e036f1a78ac441bc8d837ecbb5572c9a
Autor:
Andrea Marzi, Jackson Emanuel, Julie Callison, Kristin L. McNally, Nicolette Arndt, Spencer Chadinha, Cynthia Martellaro, Rebecca Rosenke, Dana P. Scott, David Safronetz, Stephen S. Whitehead, Sonja M. Best, Heinz Feldmann
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 8 (2018)
The common small animal disease models for Zika virus (ZIKV) are mice lacking the interferon responses, but infection of interferon receptor α/β knock out (IFNAR−/−) mice is not uniformly lethal particularly in older animals. Here we sought to
Externí odkaz:
https://doaj.org/article/acca1c64424048a7807cc7fc4e2b43ad
Autor:
Adaeze O Izuogu, Kristin L McNally, Stephen E Harris, Brian H Youseff, John B Presloid, Christopher Burlak, Jason Munshi-South, Sonja M Best, R Travis Taylor
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0179781 (2017)
Tick-borne flaviviruses (TBFVs), including Powassan virus and tick-borne encephalitis virus cause encephalitis or hemorrhagic fevers in humans with case-fatality rates ranging from 1-30%. Despite severe disease in humans, TBFV infection of natural ro
Externí odkaz:
https://doaj.org/article/5bf74743187f459c9d747618a6488809
Autor:
Shelly J, Robertson, Olivia, Bedard, Kristin L, McNally, Matthew, Lewis, Chad, Clancy, Carl, Shaia, Rebecca M, Broeckel, Abhilash I, Chiramel, Gail L, Sturdevant, Elvira, Forte, Christoph, Preuss, Candice N, Baker, Jeffrey, Harder, Catherine, Brunton, Steven, Munger, Daniel E, Sturdevant, Craig, Martens, Steven M, Holland, Nadia A, Rosenthal, Sonja M, Best
Publikováno v:
bioRxiv
Inflammation in response to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection drives severity of coronavirus disease 2019 (COVID-19), with effective versus dysregulated responses influenced by host genetics. To understand mechani
Autor:
Shelly J. Robertson, Olivia Bedard, Kristin L. McNally, Carl Shaia, Chad Clancy, Matthew Lewis, Rebecca M. Broeckel, Abhilash I. Chiramel, Jeffrey G. Shannon, Gail L. Sturdevant, Rebecca Rosenke, Sarah L. Anzick, Elvira Forte, Christoph Preuss, Candice N. Baker, Jeffrey Harder, Catherine Brunton, Steven Munger, Daniel P. Bruno, Justin B. Lack, Jacqueline M. Leung, Amirhossein Shamsaddini, Paul Gardina, Daniel E. Sturdevant, Jian Sun, Craig Martens, Steven M. Holland, Nadia A. Rosenthal, Sonja M. Best
Inflammation in response to severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection drives severity of coronavirus disease 2019 (COVID-19) and is influenced by host genetics. To understand mechanisms of inflammation, animal models that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7acc6cacad3e94dcb00d2fb0b4b8e651
https://doi.org/10.1101/2021.09.17.460664
https://doi.org/10.1101/2021.09.17.460664