Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kristin E. Yates"'
Autor:
Neena S Agrawal, Xiaomu Wei, John R. Wunderlich, Yardena Samuels, Julia C. Cronin, Todd D. Prickett, Jimmy Lin, Pedro Cruz, Steven A. Rosenberg, Kristin E. Yates
Publikováno v:
Nature Genetics. 41:1127-1132
Tyrosine phosphorylation is important in signaling pathways underlying tumorigenesis. We performed a mutational analysis of the protein tyrosine kinase (PTK) gene family in cutaneous metastatic melanoma. We identified 30 somatic mutations affecting t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d73b8fabf6dc0f4f824f234a29dda799
https://doi.org/10.1038/ng.438
https://doi.org/10.1038/ng.438
Autor:
Archibald S. Perkins, Dongxian Yue, Andrew J. Read, Sharon Lin, Kristin E. Yates, Pei Hui, Amanda C. Poholek, Bogdan Yatsula
Publikováno v:
Journal of Biological Chemistry. 280:30712-30722
The leukemia-associated protein EVI1 possesses seven zinc fingers within an N-terminal domain (amino acids 1-250) that binds to GACAAGATA. Single amino acid missense mutants of EVI1 were developed that failed to bind DNA either in vitro, as assessed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f82f590e4dc7ae2baee3227e194654f
https://doi.org/10.1074/jbc.m504293200
https://doi.org/10.1074/jbc.m504293200
Autor:
Oren Beske, George Hansen, Martyn Banks, Kristin E. Yates, Michele Agler, Yingjie Zhu, Monique Anthony, Taosheng Chen
Publikováno v:
Expert Review of Molecular Diagnostics. 5:817-829
High-content screening technologies utilize assays that monitor and quantify multiple cellular events. These assays are typically performed on a single cell type with automated microscopy and image analysis. However, in order to better understand the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4df574ddf600c425c69bfad6916d802
https://doi.org/10.1586/14737159.5.5.817
https://doi.org/10.1586/14737159.5.5.817
Publikováno v:
Aging cell. 7(5)
The proliferative lifespan of normal somatic human cells in culture terminates in a permanent growth-arrested state known as replicative senescence. In this study, we show that RNA interference-mediated repression of the genes encoding the small ubiq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b64f766f476fea29daecfee8f1706d08
https://pubmed.ncbi.nlm.nih.gov/18616636
https://pubmed.ncbi.nlm.nih.gov/18616636
Autor:
Kristin E. Yates, Donald M. Engelman, Ann M. Dixon, Lara Ely, Daniel DiMaio, Anne P. B. Edwards, Lisa L. Freeman-Cook
Publikováno v:
Journal of molecular biology. 345(4)
The 44 amino acid E5 transmembrane protein is the primary oncogene product of bovine papillomavirus. Homodimers of the E5 protein activate the cellular PDGF beta receptor tyrosine kinase by binding to its transmembrane domain and inducing receptor di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::920a98ca2c2e5b50e29f846db0b4a043
https://pubmed.ncbi.nlm.nih.gov/15588835
https://pubmed.ncbi.nlm.nih.gov/15588835
Autor:
Kristin E. Yates, Anne P. B. Edwards, Amanda Psyrri, Rosa Anna DeFilippis, L. Manuelidis, Daniel DiMaio
Publikováno v:
Cancer research. 64(9)
Repression of the endogenous human papillomavirus (HPV) type 18 E7 gene in HeLa cervical carcinoma cells by the bovine papillomavirus E2 transcription factor activates the retinoblastoma (Rb) pathway and induces cells to undergo senescence. To determ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4277cca22e8353465cf65f672bf13943
https://pubmed.ncbi.nlm.nih.gov/15126344
https://pubmed.ncbi.nlm.nih.gov/15126344
Autor:
Steven A. Rosenberg, Julia C. Cronin, Yardena Samuels, Neena S Agrawal, Pedro Cruz, J. Lin, Todd D. Prickett, Xiaomu Wei, Kristin E. Yates, John R. Wunderlich
Publikováno v:
Cancer Research. 70:2221-2221
One of the most important features of cellular signaling involves the addition (or removal) of phosphate groups. Protein phosphorylation is coordinately regulated by protein kinases and phosphatases. Protein kinases are the largest superfamily of con
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b3d397ecf1c813db01fcef72368012fa
https://doi.org/10.1158/1538-7445.am10-2221
https://doi.org/10.1158/1538-7445.am10-2221