Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Kristin E. Finch"'
Autor:
Claire E. Knezevic, Amanda C. Nottbohm, Kathryn C. Partlow, Paul J. Hergenrother, Kristin E. Finch
Publikováno v:
ACS Chemical Biology. 7:563-570
The poly(ADP-ribose) (PAR) post-translational modification is essential for diverse cellular functions, including regulation of transcription, response to DNA damage, and mitosis. Cellular PAR is predominantly synthesized by the enzyme poly(ADP-ribos
Autor:
Paul J. Hergenrother, Erich A. Lidstone, Leo Li-Ying Chan, James T. Heeres, Brian T. Cunningham, Kristin E. Finch
Publikováno v:
JALA (Charlottesville, Va.). 14(6)
Small molecules identified through high-throughput screens are an essential element in pharmaceutical discovery programs. It is now recognized that a substantial fraction of small molecules exhibit aggregating behavior leading to false positive resul
Autor:
James T. Heeres, Leo Li-Ying Chan, Erich A. Lidstone, Brian T. Cunningham, Kristin E. Finch, Paul J. Hergenrother
Publikováno v:
Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. 2009
Small molecules identified through high-throughput screens are an essential element in pharmaceutical discovery programs. It is now recognized that a substantial fraction of small molecules exhibit aggregating behavior leading to false positive resul