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Cell Type-specific Expression of LINE-1 Open Reading Frames 1 and 2 in Fetal and Adult Human Tissues
Autor:
Kristin Dammann, Heidrun Lauke, Nerbil Kilic, Süleyman Ergün, Fariba Chalajour, Wolf H. Strätling, Frank Schnieders, Gerald G. Schumann, Christian Buschmann, Jochen Heukeshoven
Publikováno v:
Journal of Biological Chemistry. 279:27753-27763
The LINE-1 (L1) family of non-long terminal repeat retrotransposons is a major force shaping mammalian genomes, and its members can alter the genome in many ways. Mutational analyses have shown that coexpression of functional proteins encoded by the