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pro vyhledávání: '"Kristin D. Holmes"'
Autor:
Filip Mundt, Jacqueline Watson, Steven A. Carr, Sitapriya Moorthi, April Lo, Iris Fung, Shriya Kamlapurkar, Kristin D. Holmes, Alice H. Berger, Shaunt Fereshetian, Philipp Mertins
Publikováno v:
Sci Signal
Aberrant activation of the RAS family of guanosine triphosphatases (GTPases) is prevalent in lung adenocarcinoma, with somatic mutation of KRAS occurring in ~30% of tumors. We previously identified somatic mutations and amplifications of the gene enc