Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Kristin Crosno"'
Autor:
Chrysanthy Ikonomidou, Sophie H. Wang, Nicole A. Fuhler, Shreya Larson, Saverio Capuano, III, Kevin R. Brunner, Kristin Crosno, Heather A. Simmons, Andres F. Mejia, Kevin K. Noguchi
Publikováno v:
Neurobiology of Disease, Vol 171, Iss , Pp 105814- (2022)
Barbiturates and benzodiazepines are GABAA-receptor agonists and potent antiseizure medications. We reported that exposure of neonatal macaques to combination of phenobarbital and midazolam (Pb/M) for 24 h, at clinically relevant doses and plasma lev
Externí odkaz:
https://doaj.org/article/0b33585d32a84a88b6448d72e5c685f0
Autor:
Ivan M. Rosado-Mendez, Kevin K. Noguchi, Laura Castañeda-Martinez, George Kirvassilis, Sophie H. Wang, Francesca Manzella, Brant S. Swiney, Kobe Masuoka, Saverio Capuano, III, Kevin G. Brunner, Kristin Crosno, Quinton W. Guerrero, Hayley Whitson, Ansgar Brambrink, Heather S. Simmons, Andres F. Mejia, James A. Zagzebski, Timothy J. Hall, Chrysanthy Ikonomidou
Publikováno v:
Neurobiology of Disease, Vol 127, Iss , Pp 554-562 (2019)
Apoptosis is triggered in the developing mammalian brain by sedative, anesthetic or antiepileptic drugs during late gestation and early life. Whether human children are vulnerable to this toxicity mechanism remains unknown, as there are no imaging te
Externí odkaz:
https://doaj.org/article/f86792d81f6c469ab5499c822c67f712
Autor:
Nuria Pedreño-Lopez, Brandon C. Rosen, Walter J. Flores, Matthew J. Gorman, Thomas B. Voigt, Michael J. Ricciardi, Kristin Crosno, Kim L. Weisgrau, Christopher L. Parks, Jeffrey D. Lifson, Galit Alter, Eva G. Rakasz, Diogo M. Magnani, Mauricio A. Martins, David I. Watkins
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
The antiviral properties of broadly neutralizing antibodies against HIV are well-documented but no vaccine is currently able to elicit protective titers of these responses in primates. While current vaccine modalities can readily induce non-neutraliz
Externí odkaz:
https://doaj.org/article/953611f23bac4fb3b5b40dc083c6c0d6
Autor:
Kevin K. Noguchi, Nicole A. Fuhler, Sophie H. Wang, Saverio Capuano, III, Kevin R. Brunner, Shreya Larson, Kristin Crosno, Heather A. Simmons, Andres F. Mejia, Lauren D. Martin, Gregory A. Dissen, Ansgar Brambrink, Chrysanthy Ikonomidou
Publikováno v:
Neurobiology of Disease, Vol 149, Iss , Pp 105245- (2021)
Barbiturates and benzodiazepines are potent GABAA receptor agonists and strong anticonvulsants. In the developing brain they can cause neuronal and oligodendroglia apoptosis, impair synaptogenesis, inhibit neurogenesis and trigger long-term neurocogn
Externí odkaz:
https://doaj.org/article/27ba63a8d3634d8a83747ee45c334675
Autor:
Aidin Tavakoli-Tameh, Sanath Kumar Janaka, Katie Zarbock, Shelby O'Connor, Kristin Crosno, Saverio Capuano, Hajime Uno, Jeffrey D Lifson, David T Evans
Publikováno v:
PLoS Pathogens, Vol 16, Iss 4, p e1008487 (2020)
Most simian immunodeficiency viruses use Nef to counteract the tetherin proteins of their nonhuman primate hosts. Nef also downmodulates cell-surface CD4 and MHC class I (MHC I) molecules and enhances viral infectivity by counteracting SERINC5. We pr
Externí odkaz:
https://doaj.org/article/b7803c4943094999a6d7b123419810b7
Autor:
Chrysanthy Ikonomidou, George Kirvassilis, Brant S. Swiney, Sophie H. Wang, Jacob N. Huffman, Sasha L. Williams, Kobe Masuoka, Saverio Capuano, III, Kevin R. Brunner, Kristin Crosno, Heather S. Simmons, Andres F. Mejia, Christopher A. Turski, Ansgar Brambrink, Kevin K. Noguchi
Publikováno v:
Neurobiology of Disease, Vol 130, Iss , Pp 104489- (2019)
Sedatives and anesthetics can injure the developing brain. They cause apoptosis of neurons and oligodendrocytes, impair synaptic plasticity, inhibit neurogenesis and trigger long-term neurocognitive deficits. The projected vulnerable period in humans
Externí odkaz:
https://doaj.org/article/eb953d7fb22749b1bfc7e244b98ecfdf
Autor:
Moritz Ries, Matthew R Reynolds, Ksenia Bashkueva, Kristin Crosno, Saverio Capuano, Trent M Prall, Roger Wiseman, David H O'Connor, Eva G Rakasz, Hajime Uno, Jeffrey D Lifson, David T Evans
Publikováno v:
PLoS Pathogens, Vol 13, Iss 7, p e1006506 (2017)
Natural killer cells provide an important early defense against viral pathogens and are regulated in part by interactions between highly polymorphic killer-cell immunoglobulin-like receptors (KIRs) on NK cells and their MHC class I ligands on target
Externí odkaz:
https://doaj.org/article/e53d514baa884b57bb0e34012045a157
Autor:
Saverio Capuano, Ansgar M. Brambrink, Kevin K. Noguchi, Kevin R. Brunner, Jacob Huffman, George Kirvassilis, Andres Mejia, Kobe Masuoka, Heather S. Simmons, Kristin Crosno, Brant S. Swiney, Sasha L. Williams, Sophie H. Wang, Chrysanthy Ikonomidou, Christopher A. Turski
Publikováno v:
Neurobiol Dis
Neurobiology of Disease, Vol 130, Iss, Pp 104489-(2019)
Neurobiology of Disease, Vol 130, Iss, Pp 104489-(2019)
Sedatives and anesthetics can injure the developing brain. They cause apoptosis of neurons and oligodendrocytes, impair synaptic plasticity, inhibit neurogenesis and trigger long-term neurocognitive deficits. The projected vulnerable period in humans
Autor:
Lauren D. Martin, Shreya Larson, Kevin K. Noguchi, Saverio Capuano, Kevin R. Brunner, Ansgar M. Brambrink, Andres Mejia, Gregory A. Dissen, Sophie H. Wang, Kristin Crosno, Nicole A. Fuhler, Heather A. Simmons, Chrysanthy Ikonomidou
Publikováno v:
Neurobiology of disease
Neurobiology of Disease, Vol 149, Iss, Pp 105245-(2021)
Neurobiology of Disease, Vol 149, Iss, Pp 105245-(2021)
Barbiturates and benzodiazepines are potent GABAA receptor agonists and strong anticonvulsants. In the developing brain they can cause neuronal and oligodendroglia apoptosis, impair synaptogenesis, inhibit neurogenesis and trigger long-term neurocogn
Loss of tetherin antagonism by Nef impairs SIV replication during acute infection of rhesus macaques
Autor:
Saverio Capuano, Kristin Crosno, Katie Zarbock, Shelby L. O’Connor, Sanath Kumar Janaka, Hajime Uno, David T. Evans, Aidin Tavakoli-Tameh, Jeffrey D. Lifson
Publikováno v:
PLoS Pathogens
PLoS Pathogens, Vol 16, Iss 4, p e1008487 (2020)
PLoS Pathogens, Vol 16, Iss 4, p e1008487 (2020)
Most simian immunodeficiency viruses use Nef to counteract the tetherin proteins of their nonhuman primate hosts. Nef also downmodulates cell-surface CD4 and MHC class I (MHC I) molecules and enhances viral infectivity by counteracting SERINC5. We pr