Výsledky vyhledávání - "Kristin C. Brodbeck"

Rapid automation of a cell-based assay using a modular approach: Case study of a flow-based Varicella Zoster Virus infectivity assay

Autor: Scott L. Barmat, Jean-Luc Bodmer, Irina V. Gates, Yuhua Zhang, Christopher J. Wang, Diana Pacchione, Tina Frey, Daniel B. Joelsson, Luca Benetti, Philip S. Bennett, Heather Baxter, Kristin C. Brodbeck, Jennifer L. McMackin

Publikováno v: Journal of Virological Methods. 166:1-11

Vaccine manufacturing requires constant analytical monitoring to ensure reliable quality and a consistent safety profile of the final product. Concentration and bioactivity of active components of the vaccine are key attributes routinely evaluated th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a39de80ae856de353301ba6760e5b7cf
https://doi.org/10.1016/j.jviromet.2010.01.016

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Serglycin proteoglycan expression and synthesis in embryonic stem cells

Autor: Kristin C. Brodbeck, Clinton W Wrigley, Joanne Klimas, Hon-Chung Keith Ho, Barbara P. Schick

Publikováno v: Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1593:259-267

The serglycin proteoglycan is expressed in most hematopoietic cells and is packaged into secretory vesicles for constitutive or regulated secretion. We have now shown serglycin mRNA expression in undifferentiated murine embryonic stem (ES) cells and

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::978ca21584d9abf924a5f09d09dc017d
https://doi.org/10.1016/s0167-4889(02)00396-8

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Serglycin Proteoglycan Synthesis in the Murine Uterine Decidua and Early Embryo1

Autor: James Palis, Kathleen E. McGrath, Kristin C. Brodbeck, Hon-Chung Keith Ho, Barbara P. Schick

Publikováno v: Biology of Reproduction. 64:1667-1676

This study has explored the localization and synthesis of the serglycin proteoglycan in the murine embryo and uterine decidua during midgestation. Embryos in deciduae were subjected to in situ hybridization with cRNA probes and to immunohistochemical

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a15990841c4e09563c9ab257a16c7ec7
https://doi.org/10.1095/biolreprod64.6.1667

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Promoter Regulatory Elements and DNase I-hypersensitive Sites Involved in Serglycin Proteoglycan Gene Expression in Human Erythroleukemia, CHRF 288-11, and HL-60 Cells

Autor: Kristin C. Brodbeck, Barbara P. Schick, Patria Castronuevo, Irina Petrushina

Publikováno v: Journal of Biological Chemistry. 276:24726-24735

We have compared regulation of the serglycin gene in human erythroleukemia (HEL) and CHRF 288-11 cells, which have megakaryocytic characteristics, with promyelocytic HL-60 cells. Deletion constructs were prepared from the region -1123/+42 to -20/+42,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::186c6d0d9969f4670d4dbe4f804c2fb2
https://doi.org/10.1074/jbc.m102958200

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Mechanisms of proliferation synergy by receptor tyrosine kinase and G protein-coupled receptor activation in human airway smooth muscle

Autor: Andrew J. Eszterhas, Michael J. Orsini, Kristin C. Brodbeck, Raymond B. Penn, Reynold A. Panettieri, Vera P. Krymskaya, Jeffrey L. Benovic

Publikováno v: American journal of respiratory cell and molecular biology. 23(4)

Despite recent studies depicting the capacity of G protein-coupled receptors (GPCRs) to activate mitogenic signaling pathways more commonly associated with receptor tyrosine kinases (RTKs), little is known regarding the interactive effects of GPCR an

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb8e33f984ff52bf01ea0b10a4b35517
https://pubmed.ncbi.nlm.nih.gov/11017921

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