Zobrazeno 1 - 10
of 108
pro vyhledávání: '"Kristin C Gunsalus"'
Autor:
Gennaro Esposito, Yamanappa Hunashal, Mathias Percipalle, Federico Fogolari, Tomas Venit, Ainars Leonchiks, Kristin C Gunsalus, Fabio Piano, Piergiorgio Percipalle
Publikováno v:
PLoS ONE, Vol 19, Iss 5, p e0303839 (2024)
The interaction between SARS-CoV-2 non-structural protein Nsp9 and the nanobody 2NSP90 was investigated by NMR spectroscopy using the paramagnetic perturbation methodology PENELOP (Paramagnetic Equilibrium vs Nonequilibrium magnetization Enhancement
Externí odkaz:
https://doaj.org/article/a0e1d5066c4b437da54641185d876771
Autor:
Elisabeth A Marnik, Miguel V Almeida, P Giselle Cipriani, George Chung, Edoardo Caspani, Emil Karaulanov, Hin Hark Gan, John Zinno, Ida J Isolehto, Fridolin Kielisch, Falk Butter, Catherine S Sharp, Roisin M Flanagan, Frederic X Bonnet, Fabio Piano, René F Ketting, Kristin C Gunsalus, Dustin L Updike
Publikováno v:
PLoS Genetics, Vol 18, Iss 6, p e1010245 (2022)
LOTUS and Tudor domain containing proteins have critical roles in the germline. Proteins that contain these domains, such as Tejas/Tapas in Drosophila, help localize the Vasa helicase to the germ granules and facilitate piRNA-mediated transposon sile
Externí odkaz:
https://doaj.org/article/71709158c8ad428c89af9008c7d82035
Autor:
Patricia Giselle Cipriani, Olivia Bay, John Zinno, Michelle Gutwein, Hin Hark Gan, Vinay K Mayya, George Chung, Jia-Xuan Chen, Hala Fahs, Yu Guan, Thomas F Duchaine, Matthias Selbach, Fabio Piano, Kristin C Gunsalus
Publikováno v:
eLife, Vol 10 (2021)
We describe MIP-1 and MIP-2, novel paralogous C. elegans germ granule components that interact with the intrinsically disordered MEG-3 protein. These proteins promote P granule condensation, form granules independently of MEG-3 in the postembryonic g
Externí odkaz:
https://doaj.org/article/5376ad2b9c1849d09f6a60306a309c25
Autor:
Jasmin Chahal, Luca FR Gebert, Hin Hark Gan, Kristin C Gunsalus, Ian J MacRae, Selena M Sagan
Publikováno v:
Proceedings, Vol 50, Iss 1, p 131 (2020)
Hepatitis C virus (HCV) is a positive-sense RNA virus that interacts with a human-liver-specific microRNA, termed miR-122. miR-122 binds to two sites in the 5' untranslated region (UTR) of the viral genome, and this interaction promotes HCV RNA accum
Externí odkaz:
https://doaj.org/article/d0f47fc2e8ad4b3583533ca6fbaf168d
Autor:
David R Nelson, Basel Khraiwesh, Weiqi Fu, Saleh Alseekh, Ashish Jaiswal, Amphun Chaiboonchoe, Khaled M Hazzouri, Matthew J O’Connor, Glenn L Butterfoss, Nizar Drou, Jillian D Rowe, Jamil Harb, Alisdair R Fernie, Kristin C Gunsalus, Kourosh Salehi-Ashtiani
Publikováno v:
eLife, Vol 6 (2017)
To investigate the phenomic and genomic traits that allow green algae to survive in deserts, we characterized a ubiquitous species, Chloroidium sp. UTEX 3007, which we isolated from multiple locations in the United Arab Emirates (UAE). Metabolomic an
Externí odkaz:
https://doaj.org/article/68f698ed5f43475691cebd2192736133
Autor:
Annalise B Paaby, Amelia G White, David D Riccardi, Kristin C Gunsalus, Fabio Piano, Matthew V Rockman
Publikováno v:
eLife, Vol 4 (2015)
Embryogenesis is an essential and stereotypic process that nevertheless evolves among species. Its essentiality may favor the accumulation of cryptic genetic variation (CGV) that has no effect in the wild-type but that enhances or suppresses the effe
Externí odkaz:
https://doaj.org/article/066f10d1b46b455c94502c3a5db80f5d
Autor:
Christopher S Poultney, Glenn L Butterfoss, Michelle R Gutwein, Kevin Drew, David Gresham, Kristin C Gunsalus, Dennis E Shasha, Richard Bonneau
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e23947 (2011)
Temperature-sensitive (ts) mutations are mutations that exhibit a mutant phenotype at high or low temperatures and a wild-type phenotype at normal temperature. Temperature-sensitive mutants are valuable tools for geneticists, particularly in the stud
Externí odkaz:
https://doaj.org/article/d87c77423b1e495180a8889c2c44011f
Publikováno v:
PLoS Computational Biology, Vol 1, Iss 1, p e13 (2005)
microRNAs are small noncoding genes that regulate the protein production of genes by binding to partially complementary sites in the mRNAs of targeted genes. Here, using our algorithm PicTar, we exploit cross-species comparisons to predict, on averag
Externí odkaz:
https://doaj.org/article/62d24383733a472ab55c38e6b9b229dd
Publikováno v:
Genome Biology. 24
Background Recent work has demonstrated that three-dimensional genome organization is directly affected by changes in the levels of nuclear cytoskeletal proteins such as β-actin. The mechanisms which translate changes in 3D genome structure into cha
Publikováno v:
Frontiers in Virology. 2
High transmissibility is a hallmark of the Omicron variant of SARS-CoV-2. Understanding the molecular determinants of Omicron’s transmissibility will impact development of intervention strategies. Here we map the electrostatic potential surface of