Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Kristin Beaudry"'
Autor:
Gary J. Nabel, Darci A. Gorgone, Dan H. Barouch, Brent Welcher, Michelle A. Lifton, Bimal K. Chakrabarti, John R. Mascola, Kristin Beaudry, Norman L. Letvin, Michael S. Seaman, Yue Huang, Krisha Svehla, Ling Xu, Zhi Yong Yang, Sampa Santra, Carol I. Lord
Publikováno v:
Journal of Virology. 79:6516-6522
The magnitude and durability of immune responses induced by replication-defective adenovirus serotype 5 (ADV5) vector-based vaccines were evaluated in the simian-human immunodeficiency virus/rhesus monkey model. A single inoculation of recombinant AD
Autor:
Kimberly A. Zinnack, Norman L. Letvin, Kristin Beaudry, Alicia Gómez Yafal, Petr O. Ilyinskii, Dennis Panicali, Kelledy Manson, Shawn S. Jackson, Valerie Philippon, Marcelo J. Kuroda, Linda Gritz, Michelle A. Lifton, Gail P. Mazzara
Publikováno v:
Journal of Virology. 79:6554-6559
Poxvirus vaccine vectors, although capable of eliciting potent immune responses, pose serious health risks in immunosuppressed individuals. We therefore constructed five novel recombinant vaccinia virus vectors which contained overlapping deletions o
Autor:
Michael S. Seaman, Ayako Miura, Olga G. Golubeva, Bimal K. Chakrabarti, Ling Xu, Birgit Korioth-Schmitz, Faye Yu, Yue Huang, Wing Pui Kong, Zhi Yong Yang, Norman L. Letvin, John R. Mascola, Kristi L. Martin, David C. Montefiori, Kristin Beaudry, Gary J. Nabel, Daniela Rohne, Rebecca Gelman
Publikováno v:
Journal of Virology. 78:7490-7497
Because a strategy to elicit broadly neutralizing anti-human immunodeficiency virus type 1 (HIV-1) antibodies has not yet been found, the role of an Env immunogen in HIV-1 vaccine candidates remains undefined. We sought to determine whether an HIV-1
Autor:
Marcelo J. Kuroda, Kristin Beaudry, Jennifer Kunstman, Dan H. Barouch, Sampa Santra, Jörn E. Schmitz, Fred W. Peyerl, Georgia R. Krivulka, Darci A. Gorgone, Michelle A. Lifton, Steven M. Wolinsky, Mark G. Lewis, David C. Montefiori, Norman L. Letvin
Publikováno v:
Nature. 415:335-339
Potent virus-specific cytotoxic T lymphocyte (CTL) responses elicited by candidate AIDS vaccines have recently been shown to control viral replication and prevent clinical disease progression after pathogenic viral challenges in rhesus monkeys. Here
Autor:
Kristin Beaudry, Keith A. Reimann, Abie Craiu, Tavis D. Steenbeke, Michelle A. Lifton, Dan H. Barouch, Julie D. Frost, Norman L. Letvin, Marcelo J. Kuroda, Terry B. Strom, Christy E. Nickerson, Joern E. Schmitz, Xin Xiao Zheng
Publikováno v:
AIDS Research and Human Retroviruses. 17:873-886
The T cell-stimulatory cytokine interleukin 2 (IL-2) is being evaluated as a therapeutic in the clinical settings of HIV infection and cancer. However, the clinical utility of IL-2 may be mitigated by its short in vivo half-life, toxic effects, and h
Autor:
Steven B. Koevary, Kristin Beaudry
Publikováno v:
Ocular Immunology and Inflammation. 8:39-47
Anterior chamber-associated immune deviation (ACAID) is characterized by the systemic inhibition of delayed type hypersensitivity (DTH) reactions to antigens which have previously been placed into the anterior chamber of the eye. Since its initial ch
Autor:
John R. Mascola, David C. Montefiori, Ronald S. Veazey, Lauren Peterson, Norman L. Letvin, Gary J. Nabel, Keith A. Reimann, Kenneth C. Williams, Kristin Beaudry, Robert A. Parker, Michael S. Seaman, Margaret H. Beddall
Because most studies of AIDS pathogenesis in nonhuman primates have been performed in Indian-origin rhesus macaques ( Macaca mulatta ), little is known about lentiviral pathogenicity and control of virus replication following infection of alternative
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4281a313189710966b5209e1d878b785
https://europepmc.org/articles/PMC1168747/
https://europepmc.org/articles/PMC1168747/
Autor:
Holden T. Maecker, John R. Mascola, Dan H. Barouch, Jörn E. Schmitz, Ramu A. Subbramanian, Kelledy Manson, Yue Sun, Michelle A. Lifton, Norman L. Letvin, Ling Xu, Dennis Panicali, Darci A. Gorgone, Kristin Beaudry, Sampa Santra, Valerie Philippon, Paula M. Acierno, Gary J. Nabel
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 174(8)
Production of IL-2 and IFN-γ by CD4+ T lymphocytes is important for the maintenance of a functional immune system in infected individuals. In the present study, we assessed the cytokine production profiles of functionally distinct subsets of CD4+ T
Autor:
Kristi L. Martin, Ling Xu, Robert T. Bailer, John R. Mascola, Bimal K. Chakrabarti, Michael S. Seaman, Gary J. Nabel, Ayako Miura, Richard A. Koup, Yue Huang, Anna Sambor, Kristin Beaudry, Norman L. Letvin, Margaret H. Beddall
Publikováno v:
Journal of virology. 79(5)
The development of a human immunodeficiency virus type 1 (HIV-1) vaccine that elicits potent cellular and humoral immune responses recognizing divergent strains of HIV-1 will be critical for combating the global AIDS epidemic. The present studies wer
Autor:
Zhi Yong Yang, Wing Pui Kong, Brent Welcher, Kristin Beaudry, Norman L. Letvin, Thomas C. VanCott, Gary J. Nabel, Mark K. Louder, John R. Mascola, Bimal K. Chakrabarti, Yue Huang, Anna Sambor, David C. Montefiori, Ling Xu, Sampa Santra
Publikováno v:
Journal of virology. 79(2)
Immunization with recombinant serotype 5 adenoviral (rAd5) vectors or a combination of DNA plasmid priming and rAd5 boosting is known to elicit potent immune responses. However, little data exist regarding these immunization strategies and the develo