Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Kristin Baetz"'
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 11, Iss 11 (2021)
AbstractMetagenomic profiling of the human gut microbiome has discovered DNA from dietary yeasts like Saccharomyces cerevisiaeS. cerevisiaeS. cerevisiaeCandida albicansS. cerevisiaeS. cerevisiaeYCR095W-AC. albicans
Externí odkaz:
https://doaj.org/article/b225a00e5e6a478ea2b0b29d69bf5776
Publikováno v:
iScience, Vol 24, Iss 4, Pp 102327- (2021)
Summary: Adipic acid production by yeast fermentation is gaining attention as a renewable source of platform chemicals for making nylon products. However, adipic acid toxicity inhibits yeast growth and fermentation. Here, we performed a chemogenomic
Externí odkaz:
https://doaj.org/article/63da561d21b64135a85e520d9e7fcb51
Autor:
Elizabeth A Walden, Roger Y Fong, Trang T Pham, Hana Knill, Sarah Jane Laframboise, Sylvain Huard, Mary-Ellen Harper, Kristin Baetz
Publikováno v:
PLoS Genetics, Vol 16, Iss 11, p e1009220 (2020)
Cellular metabolism is tightly regulated by many signaling pathways and processes, including lysine acetylation of proteins. While lysine acetylation of metabolic enzymes can directly influence enzyme activity, there is growing evidence that lysine a
Externí odkaz:
https://doaj.org/article/7aaf5f105fb142c8a4a4c97aed7e0c45
Autor:
Eugene Fletcher, Kristin Baetz
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 8 (2020)
Synthetic biology has played a major role in engineering microbial cell factories to convert plant biomass (lignocellulose) to fuels and bioproducts by fermentation. However, the final product yield is limited by inhibition of microbial growth and fe
Externí odkaz:
https://doaj.org/article/76b4feac4134448584b00fa235af0c2f
Autor:
Louis Dacquay, Annika Flint, James Butcher, Danny Salem, Michael Kennedy, Mads Kaern, Alain Stintzi, Kristin Baetz
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 7, Iss 6, Pp 1799-1809 (2017)
Actively proliferating cells constantly monitor and readjust their metabolic pathways to ensure the replenishment of phospholipids necessary for membrane biogenesis and intracellular trafficking. In Saccharomyces cerevisiae, multiple studies have sug
Externí odkaz:
https://doaj.org/article/0f1be6d03df244588a4133165f36ffd7
Autor:
Meaghen Rollins, Sylvain Huard, Alan Morettin, Jennifer Takuski, Trang Thuy Pham, Morgan D Fullerton, Jocelyn Côté, Kristin Baetz
Publikováno v:
PLoS Genetics, Vol 13, Iss 2, p e1006626 (2017)
Eukaryotic cells form stress granules under a variety of stresses, however the signaling pathways regulating their formation remain largely unknown. We have determined that the Saccharomyces cerevisiae lysine acetyltransferase complex NuA4 is require
Externí odkaz:
https://doaj.org/article/96a1eee42e0d4eae868d2f2d0c859d79
Autor:
Jean‐Philippe Lambert, Jeffrey Fillingham, Mojgan Siahbazi, Jack Greenblatt, Kristin Baetz, Daniel Figeys
Publikováno v:
Molecular Systems Biology, Vol 6, Iss 1, Pp 1-16 (2010)
Abstract We previously reported a novel affinity purification (AP) method termed modified chromatin immunopurification (mChIP), which permits selective enrichment of DNA‐bound proteins along with their associated protein network. In this study, we
Externí odkaz:
https://doaj.org/article/7a3e472c202948a0954b19308bf7f673
Autor:
Michael A Kennedy, Kenneth Gable, Karolina Niewola-Staszkowska, Susana Abreu, Anne Johnston, Linda J Harris, Fulvio Reggiori, Robbie Loewith, Teresa Dunn, Steffany A L Bennett, Kristin Baetz
Publikováno v:
PLoS Genetics, Vol 10, Iss 1, p e1004010 (2014)
Unbiased lipidomic approaches have identified impairments in glycerophosphocholine second messenger metabolism in patients with Alzheimer's disease. Specifically, we have shown that amyloid-β42 signals the intraneuronal accumulation of PC(O-16:0/2:0
Externí odkaz:
https://doaj.org/article/c7e06b2f45804822aea12b8b20a5a089
Autor:
Michael A Kennedy, Nazir Kabbani, Jean-Philippe Lambert, Leigh Anne Swayne, Fida Ahmed, Daniel Figeys, Steffany A L Bennett, Jennnifer Bryan, Kristin Baetz
Publikováno v:
PLoS Genetics, Vol 7, Iss 2, p e1001299 (2011)
During Alzheimer's Disease, sustained exposure to amyloid-β₄₂ oligomers perturbs metabolism of ether-linked glycerophospholipids defined by a saturated 16 carbon chain at the sn-1 position. The intraneuronal accumulation of 1-O-hexadecyl-2-acety
Externí odkaz:
https://doaj.org/article/c740e768ae3545188d826512e6fe04b5
Autor:
Leslie Mitchell, Andrea Lau, Jean-Philippe Lambert, Hu Zhou, Ying Fong, Jean-François Couture, Daniel Figeys, Kristin Baetz
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e25336 (2011)
In the budding yeast Saccharomyces cerevisiae, the lysine acetyltransferase NuA4 has been linked to a host of cellular processes through the acetylation of histone and non-histone targets. To discover proteins regulated by NuA4-dependent acetylation,
Externí odkaz:
https://doaj.org/article/8dbb1953758447f79ea6206cff17d3b2