Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Kristin B. O'berry"'
Autor:
Yu Zoe Zhang, Jared S. Bee, Megan Kuhn Phillippi, Kristin B. O'berry, Roberto A DePaz, Akanksha Kaushal, Tristan Marshall
Publikováno v:
Journal of pharmaceutical sciences. 110(9)
Adeno-associated virus (AAV) vectors for gene therapy have potential to provide a durable treatment response for a number of diseases with unmet need. DNA is released from AAV capsids at high temperatures. Less is known about DNA release that may occ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::81e24c8407bf83abf24319290077bc60
https://pubmed.ncbi.nlm.nih.gov/34107283
https://pubmed.ncbi.nlm.nih.gov/34107283
Autor:
Srivalli Telikepalli, Sangeeta B. Joshi, Kristin B. O'berry, C. Russell Middaugh, Ozan S. Kumru, Jae Hyun Kim, Angela W. Blake-Haskins, David B. Volkin, Melissa D. Perkins
Publikováno v:
Journal of Pharmaceutical Sciences. 104:495-507
Upon exposure to shaking stress, an IgG1 mAb formulation in both the liquid and lyophilized state formed subvisible particles. Because freeze-drying was expected to minimize protein physical instability under these conditions, the extent and nature o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3da9250c53e4032458ee871af60e0ace
https://doi.org/10.1002/jps.24242
https://doi.org/10.1002/jps.24242
Autor:
Angela W. Blake-Haskins, Kristin B. O'berry, Pinaki Basu, Theodore W. Randolph, John F. Carpenter
Publikováno v:
Journal of Pharmaceutical Sciences. 103:427-436
Silicone oil used as a lubricant in prefilled syringes has the potential to induce formation of particles in protein formulations. In the current study, we used a therapeutic fusion protein, albinterferon α2b , to evaluate protein aggregation and pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d23bcb2643ab1accc5250827b6056883
https://doi.org/10.1002/jps.23821
https://doi.org/10.1002/jps.23821