Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Kristin Arnsburg"'
Autor:
Barbara Mlody, Josef Priller, Manuel Iburg, Janine Kirstein, Alexander Buntru, Maria Lucia Pigazzini, Katrin Juenemann, Anne Ast, Alessandro Prigione, Erich E. Wanker, Annika Scior, Kristin Arnsburg, Dmytro Puchkov
Publikováno v:
EMBO J
Huntington9s disease (HD) is a neurodegenerative disorder caused by an expanded CAG trinucleotide repeat in the huntingtin gene ( HTT ). Molecular chaperones have been implicated in suppressing or delaying the aggregation of mutant Htt. Using in vitr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::454bf88c184e1f306444a067dbf67a0b
https://doi.org/10.15252/embj.2021109413
https://doi.org/10.15252/embj.2021109413
Autor:
Norbert Sträter, John T. Heiker, Kristin Arnsburg, Kathrin Oertwig, Anja Saalbach, Jan Pippel, David Ulbricht
Many members of the serine protease inhibitor (serpin) family are activated by glycosaminoglycans (GAGs). Visceral adipose tissue-derived serpin (vaspin), serpin A12 of the serpin family, and its target protease kallikrein 7 (KLK7) are heparin-bindin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0298ca771bf05e115c04ee20b0eee6b
https://ul.qucosa.de/id/qucosa:33433
https://ul.qucosa.de/id/qucosa:33433
Autor:
Bernd Bukau, Richard I. Morimoto, Kristin Arnsburg, Anna Szlachcic, Annika Scior, D. Lys Guilbride, Nadinath B. Nillegoda, Janine Kirstein
Publikováno v:
Aging cell, Early View
Aging Cell
Aging Cell
Summary Protein aggregation is enhanced upon exposure to various stress conditions and aging, which suggests that the quality control machinery regulating protein homeostasis could exhibit varied capacities in different stages of organismal lifespan.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cbbe21911b52952315bacbdaf6db4dc
Wiley Online Library
Wiley Online Library
Publikováno v:
Current genomics, 15(1): 66-75
Current Genomics
Current Genomics
The production of newly synthesized proteins is a key process of protein homeostasis that initiates the biosynthetic flux of proteins and thereby determines the composition, stability and functionality of the proteome. Protein synthesis is highly reg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5bd67108917ef49d5e19191a95b16179
https://doi.org/10.2174/1389202915666140210210542
https://doi.org/10.2174/1389202915666140210210542
Autor:
Xuechao Gao, Matthias P. Mayer, Janine Kirstein, Bernd Bukau, Kristin Arnsburg, Florian Stengel, Antonia Stank, Ruedi Aebersold, Mykhaylo Berynskyy, Annika Scior, Rebecca C. Wade, Anna Szlachcic, D. Lys Guilbride, Nadinath B. Nillegoda, Richard I. Morimoto
Publikováno v:
Nature, 524(7564):247–251
Protein aggregates are the hallmark of stressed and ageing cells, and characterize several pathophysiological states1, 2. Healthy metazoan cells effectively eliminate intracellular protein aggregates3, 4, indicating that efficient disaggregation and/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c357cad2dfa2b8ad02a0f055a6753fc8
Publikováno v:
Worm, 5(2): e1170273
The subcellular compartments of eukaryotic cells are characterized by different redox environments. Whereas the cytosol, nucleus and mitochondria are more reducing, the endoplasmic reticulum represents a more oxidizing environment. As the redox level
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3629bac8fd23fdddc2d04b6689be0e23
https://doi.org/10.1080/21624054.2016.1170273
https://doi.org/10.1080/21624054.2016.1170273