Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Kristin Alfaro"'
Autor:
Abdelrahman Yousef, Mahmoud Yousef, Saikat Chowdhury, Kawther Abdilleh, Mark Knafl, Paul Edelkamp, Kristin Alfaro-Munoz, Ray Chacko, Jennifer Peterson, Brandon G. Smaglo, Robert A. Wolff, Shubham Pant, Michael S. Lee, Jason Willis, Michael Overman, Sudheer Doss, Lynn Matrisian, Mark W. Hurd, Rebecca Snyder, Matthew H. G. Katz, Huamin Wang, Anirban Maitra, John Paul Shen, Dan Zhao
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-13 (2024)
Abstract The relevance of KRAS mutation alleles to clinical outcome remains inconclusive in pancreatic adenocarcinoma (PDAC). We conducted a retrospective study of 803 patients with PDAC (42% with metastatic disease) at MD Anderson Cancer Center. Ove
Externí odkaz:
https://doaj.org/article/07e4c9e5f98d41abaef00dd9155ae1ad
Autor:
John F. de Groot, Shiao-Pei Weathers, W.K. Alfred Yung, Gordon B. Mills, Roel G. Verhaak, Ken Chen, Gregory N. Fuller, Funda Meric-Bernstam, Kenna R. Mills Shaw, Agda Karina Eterovic, Fang Wang, Xiaojing Wang, Wei Wei, Kristin Alfaro-Munoz, Siyuan Zheng
Univariate and multivariate survival analysis.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50b8473b6693fae6d22ff38138ad539e
https://doi.org/10.1158/1535-7163.22504552
https://doi.org/10.1158/1535-7163.22504552
Autor:
John F. de Groot, Shiao-Pei Weathers, W.K. Alfred Yung, Gordon B. Mills, Roel G. Verhaak, Ken Chen, Gregory N. Fuller, Funda Meric-Bernstam, Kenna R. Mills Shaw, Agda Karina Eterovic, Fang Wang, Xiaojing Wang, Wei Wei, Kristin Alfaro-Munoz, Siyuan Zheng
S1 shows intratumor mutation heterogeneity between two specimens of one tumor. S2 describes mutational load of the patient cohort. S3 shows survival difference based on histology. S4 shows mutational signature.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6018bd5dae5deda8860fc1eefe9995e5
https://doi.org/10.1158/1535-7163.22504561
https://doi.org/10.1158/1535-7163.22504561
Autor:
John F. de Groot, Shiao-Pei Weathers, W.K. Alfred Yung, Gordon B. Mills, Roel G. Verhaak, Ken Chen, Gregory N. Fuller, Funda Meric-Bernstam, Kenna R. Mills Shaw, Agda Karina Eterovic, Fang Wang, Xiaojing Wang, Wei Wei, Kristin Alfaro-Munoz, Siyuan Zheng
Malignant gliomas are a group of intracranial cancers associated with disproportionately high mortality and morbidity. Here, we report ultradeep targeted sequencing of a prospective cohort of 237 tumors from 234 patients consisting of both glioblasto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9da58b228b561d02d5462a2a9d9129f
https://doi.org/10.1158/1535-7163.c.6537775.v1
https://doi.org/10.1158/1535-7163.c.6537775.v1
Autor:
Timothy A Gregory, Garret L Williford, Jacob M Maronge, Kristin Alfaro, Gregory N Fuller, John de Groot, Vinay K Puduvalli, Leomar Y Ballester, Nazanin K Majd
Publikováno v:
Neuro-Oncology. 25:808-809
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a77331a1783a61c7242c48efe1c0bcf
https://doi.org/10.1093/neuonc/noad007
https://doi.org/10.1093/neuonc/noad007
Autor:
Frederick F. Lang, Kaitlin Gandy, Arshad Khan, John de Groot, Emmanuel Martinez-Ledesma, Shayak Sen, Sabbir Khan, Erik P. Sulman, Nazanin Majd, Kristin Alfaro-Munoz, Rajasekaran Mahalingam, Veerakumar Balasubramaniyan
Publikováno v:
Cancers, Vol 13, Iss 5284, p 5284 (2021)
Cancers
Volume 13
Issue 21
Cancers
Volume 13
Issue 21
Interferon (IFN) signaling contributes to stemness, cell proliferation, cell death, and cytokine signaling in cancer and immune cells
however, the role of IFN signaling in glioblastoma (GBM) and GBM stem-like cells (GSCs) is unclear. Here, we in
however, the role of IFN signaling in glioblastoma (GBM) and GBM stem-like cells (GSCs) is unclear. Here, we in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::782b283d2d2efe55095ff35a09028fb6
https://www.mdpi.com/2072-6694/13/21/5284
https://www.mdpi.com/2072-6694/13/21/5284
Autor:
Jacob Mandel, Padmanee Sharma, Ganesh Rao, Shouhao Zhou, Jorge Blando, Be Lian Pei, Jimin Wu, Kathy Hunter, Monica Loghin, Shalini S. Yadav, Gregory N. Fuller, Sujit S. Prabhu, Ying Yuan, Frederick F. Lang, Rivka R. Colen, Raymond Sawaya, W. K. Alfred Yung, Carlos Kamiya Matsouka, Jeffrey S. Weinberg, Jason T. Huse, Amy B. Heimberger, James P. Allison, Kristin Alfaro-Munoz, Sherise D. Ferguson, John de Groot, Ian E. McCutcheon, Barbara O’Brien, Luis M Vence, Marta Penas-Prado, Shiao Pei Weathers
Publikováno v:
Neuro Oncol
Background We sought to ascertain the immune effector function of pembrolizumab within the glioblastoma (GBM) microenvironment during the therapeutic window. Methods In an open-label, single-center, single-arm phase II “window-of-opportunity” tri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::607f0e315165e0e23a7ca76519f6e103
https://doi.org/10.1093/neuonc/noz185
https://doi.org/10.1093/neuonc/noz185
Autor:
Shiao Pei Weathers, Shelli R. Kesler, Hannah Dyson, Kristin Alfaro-Munoz, John de Groot, Rebecca Harrison, Vikram Rao, Melissa Petersen
Publikováno v:
Oncotarget
// Shelli R. Kesler 1 , 2 , * , Rebecca A. Harrison 3 , * , Melissa L. Petersen 3 , Vikram Rao 1 , 2 , Hannah Dyson 3 , Kristin Alfaro-Munoz 3 , Shiao-Pei Weathers 3 and John de Groot 3 1 Cancer Neuroscience Laboratory, School of Nursing, The Univers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9c7b31e1be3a22bc05eeaa11c356ca2
http://europepmc.org/articles/PMC6849657
http://europepmc.org/articles/PMC6849657
Autor:
Funda Meric-Bernstam, Roel G.W. Verhaak, Shiao Pei Weathers, Gordon B. Mills, Gregory N. Fuller, Siyuan Zheng, Fang Wang, Kenna R. Mills Shaw, Ken Chen, Wei Wei, John de Groot, Agda Karina Eterovic, Kristin Alfaro-Munoz, W. K. Alfred Yung, Xiaojing Wang
Publikováno v:
Mol Cancer Ther
Malignant gliomas are a group of intracranial cancers associated with disproportionately high mortality and morbidity. Here, we report ultradeep targeted sequencing of a prospective cohort of 237 tumors from 234 patients consisting of both glioblasto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0df676fa6a5b815bf288d864d8fae5e
https://doi.org/10.1158/1535-7163.mct-18-1122
https://doi.org/10.1158/1535-7163.mct-18-1122
Autor:
Lucy F. Stead, Daniel J. Brat, Michael D. Jenkinson, Michael Schuster, Michael Weller, Hiromichi Suzuki, Raul Rabadan, Kristin Alfaro, Do-Hyun Nam, D. Ryan Ormond, Gaetano Finocchiaro, Anzhela D. Moskalik, Hoon Kim, Jason K. Sa, Mustafa Khasraw, Chew Yee Ngan, Andrew E. Sloan, Peter Gould, Mark R. Gilbert, Ganesh Rao, Michael N. C. Fletcher, Brian L. Shaw, Houtan Noushmehr, Ketan R. Bulsara, Naema Nayyar, Elizabeth B. Claus, Colin Watts, Samirkumar B. Amin, Pim J. French, Rameen Beroukhim, Azzam Ismail, Erwin G. Van Meir, Matthew R. Grimmer, Andrew R Brodbelt, Joseph F. Costello, W. K. Alfred Yung, Susan C Short, Meihong Li, Guido Reifenberger, Adelheid Woehrer, Aruna Chakrabarty, Hui K Gan, Keith L. Ligon, Roel G.W. Verhaak, Chul-Kee Park, Simone P. Niclou, Georgette Tanner, Frederick S. Varn, Arnab Chakravarti, Javad Noorbakhsh, Floris P. Barthel, Jason T. Huse, Christoph Bock, Annette M. Molinaro, Georg Widhalm, Alexander F. Bruns, Olajide Abiola, Tathiane M. Malta, Pieter Wesseling, Tali Mazor, Donát Alpár, Peter Lichter, Jill S. Barnholtz-Sloan, Priscilla K. Brastianos, Antonio Iavarone, Laila M. Poisson, Jennifer Connelly, Bernhard Radlwimmer, Gelareh Zadeh, David M. Ashley, Ho Keung Ng, Ghazaleh Tabatabai, Peter A. E. Sillevis Smitt, Mathilde C.M. Kouwenhoven, Elizabeth J. Cochran, Jeffrey H. Chuang, Pratiti Bandopadhayay, Kevin C. Johnson, Marion Smits, Allison Lowman, John de Groot, Kevin J. Anderson, Johanna M. Niers, Bart A. Westerman, Peter S. LaViolette, Emre Kocakavuk, Kenneth Aldape, Kerrie L. McDonald
Publikováno v:
Nature, vol 576, iss 7785
Nature, 576(7785), 112-120. Nature Publishing Group
Nature
Barthel, F P, Johnson, K C, Varn, F S, Moskalik, A D, Tanner, G, Kocakavuk, E, Anderson, K J, Abiola, O, Aldape, K, Alfaro, K D, Alpar, D, Amin, S B, Ashley, D M, Bandopadhayay, P, Barnholtz-Sloan, J S, Beroukhim, R, Bock, C, Brastianos, P K, Brat, D J, Brodbelt, A R, Bruns, A F, Bulsara, K R, Chakrabarty, A, Chakravarti, A, Chuang, J H, Claus, E B, Cochran, E J, Connelly, J, Costello, J F, Finocchiaro, G, Fletcher, M N, French, P J, Gan, H K, Gilbert, M R, Gould, P V, Grimmer, M R, Iavarone, A, Ismail, A, Jenkinson, M D, Khasraw, M, Kim, H, Kouwenhoven, M C M, LaViolette, P S, Li, M, Lichter, P, Ligon, K L, Lowman, A K, Malta, T M, Mazor, T, McDonald, K L, Molinaro, A M, Nam, D H, Nayyar, N, Ng, H K, Ngan, C Y, Niclou, S P, Niers, J M, Noushmehr, H, Noorbakhsh, J, Ormond, D R, Park, C K, Poisson, L M, Rabadan, R, Radlwimmer, B, Rao, G, Reifenberger, G, Sa, J K, Schuster, M, Shaw, B L, Short, S C, Smitt, P A S, Sloan, A E, Smits, M, Suzuki, H, Tabatabai, G, Van Meir, E G, Watts, C, Weller, M, Wesseling, P, Westerman, B A, Widhalm, G, Woehrer, A, Yung, W K A, Zadeh, G, Huse, J T, De Groot, J F, Stead, L F, Verhaak, R G W & The GLASS Consortium 2019, ' Longitudinal molecular trajectories of diffuse glioma in adults ', Nature, vol. 576, no. 7785, pp. 112-120 . https://doi.org/10.1038/s41586-019-1775-1, https://doi.org/10.1038/s41586-019-1775-1
Nature, 576(7785), 112-120. Nature Publishing Group
Nature
Barthel, F P, Johnson, K C, Varn, F S, Moskalik, A D, Tanner, G, Kocakavuk, E, Anderson, K J, Abiola, O, Aldape, K, Alfaro, K D, Alpar, D, Amin, S B, Ashley, D M, Bandopadhayay, P, Barnholtz-Sloan, J S, Beroukhim, R, Bock, C, Brastianos, P K, Brat, D J, Brodbelt, A R, Bruns, A F, Bulsara, K R, Chakrabarty, A, Chakravarti, A, Chuang, J H, Claus, E B, Cochran, E J, Connelly, J, Costello, J F, Finocchiaro, G, Fletcher, M N, French, P J, Gan, H K, Gilbert, M R, Gould, P V, Grimmer, M R, Iavarone, A, Ismail, A, Jenkinson, M D, Khasraw, M, Kim, H, Kouwenhoven, M C M, LaViolette, P S, Li, M, Lichter, P, Ligon, K L, Lowman, A K, Malta, T M, Mazor, T, McDonald, K L, Molinaro, A M, Nam, D H, Nayyar, N, Ng, H K, Ngan, C Y, Niclou, S P, Niers, J M, Noushmehr, H, Noorbakhsh, J, Ormond, D R, Park, C K, Poisson, L M, Rabadan, R, Radlwimmer, B, Rao, G, Reifenberger, G, Sa, J K, Schuster, M, Shaw, B L, Short, S C, Smitt, P A S, Sloan, A E, Smits, M, Suzuki, H, Tabatabai, G, Van Meir, E G, Watts, C, Weller, M, Wesseling, P, Westerman, B A, Widhalm, G, Woehrer, A, Yung, W K A, Zadeh, G, Huse, J T, De Groot, J F, Stead, L F, Verhaak, R G W & The GLASS Consortium 2019, ' Longitudinal molecular trajectories of diffuse glioma in adults ', Nature, vol. 576, no. 7785, pp. 112-120 . https://doi.org/10.1038/s41586-019-1775-1, https://doi.org/10.1038/s41586-019-1775-1
The evolutionary processes that drive universal therapeutic resistance in adult patients with diffuse glioma remain unclear1,2. Here we analysed temporally separated DNA-sequencing data and matched clinical annotation from 222 adult patients with gli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::42aa714cc58ed5e72980caca94e04350
https://pure.eur.nl/en/publications/b9198630-2a42-471b-be97-3c7b0986e7d4
https://pure.eur.nl/en/publications/b9198630-2a42-471b-be97-3c7b0986e7d4