Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Kristin A Kwakwa"'
Autor:
Francesca Fontana, Alison K Esser, Christopher Egbulefu, Partha Karmakar, Xinming Su, John S Allen, Yalin Xu, Jennifer L Davis, Ariel Gabay, Jingyu Xiang, Kristin A Kwakwa, Brad Manion, Suzanne Bakewell, Shunqiang Li, Haeseong Park, Gregory M Lanza, Samuel Achilefu, Katherine N Weilbaecher
Publikováno v:
PLoS ONE, Vol 18, Iss 12, p e0293700 (2023)
BackgroundConjugation of transferrin (Tf) to imaging or nanotherapeutic agents is a promising strategy to target breast cancer. Since the efficacy of these biomaterials often depends on the overexpression of the targeted receptor, we set out to surve
Externí odkaz:
https://doaj.org/article/900e008d55c449cf9eddf7877d941a4a
Autor:
Katherine N. Weilbaecher, Gregory M. Lanza, Deborah J. Veis, Samuel Achilefu, Vijay Sharma, James A.J. Fitzpatrick, Suzanne J. Bakewell, Christopher A. Maher, Sheila A. Stewart, Jothilingam Sivapackiam, Ha X. Dang, Kristen Pagliai, Elizabeth Cordell, Alison K. Esser, Jingyu Xiang, Francesca Fontana, Michael H. Ross, Kristin A. Kwakwa, Yalin Xu, Jennifer L. Davis, Xinming Su, Gregory C. Fox
Flow cytometric analysis of integrin β3 staining on breast cancer cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43e9581b72d1638425a68a9cf4116a21
https://doi.org/10.1158/1535-7163.22521954
https://doi.org/10.1158/1535-7163.22521954
Autor:
Katherine N. Weilbaecher, Gregory M. Lanza, Deborah J. Veis, Samuel Achilefu, Vijay Sharma, James A.J. Fitzpatrick, Suzanne J. Bakewell, Christopher A. Maher, Sheila A. Stewart, Jothilingam Sivapackiam, Ha X. Dang, Kristen Pagliai, Elizabeth Cordell, Alison K. Esser, Jingyu Xiang, Francesca Fontana, Michael H. Ross, Kristin A. Kwakwa, Yalin Xu, Jennifer L. Davis, Xinming Su, Gregory C. Fox
Breast cancer bone metastases are common and incurable. Tumoral integrin β3 (β3) expression is induced through interaction with the bone microenvironment. Although β3 is known to promote bone colonization, its functional role during therapy of est
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e9742668dcb390c0c8c105e42940932
https://doi.org/10.1158/1535-7163.c.6543234.v1
https://doi.org/10.1158/1535-7163.c.6543234.v1
Autor:
Katherine N. Weilbaecher, Gregory M. Lanza, Deborah J. Veis, Samuel Achilefu, Vijay Sharma, James A.J. Fitzpatrick, Suzanne J. Bakewell, Christopher A. Maher, Sheila A. Stewart, Jothilingam Sivapackiam, Ha X. Dang, Kristen Pagliai, Elizabeth Cordell, Alison K. Esser, Jingyu Xiang, Francesca Fontana, Michael H. Ross, Kristin A. Kwakwa, Yalin Xu, Jennifer L. Davis, Xinming Su, Gregory C. Fox
Additional details for methods and materials.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9309dd7771e5cd446cd418e97885e924
https://doi.org/10.1158/1535-7163.22521936.v1
https://doi.org/10.1158/1535-7163.22521936.v1
Autor:
Ushashi C. Dadwal, Alyssa R. Merkel, Jonathan M. Page, Kristin A. Kwakwa, Michael Kessler, Julie A. Rhoades
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 18, p 6913 (2020)
Patients with advanced skeletal metastases arising from primary cancers including breast, lung, and prostate suffer from extreme pain, bone loss, and frequent fractures. While the importance of interactions between bone and tumors is well-established
Externí odkaz:
https://doaj.org/article/f82a768982a74fd9bd2305796683aa94
Autor:
Samuel Achilefu, Michael H. Ross, Jingyu Xiang, Kristin A. Kwakwa, Elizabeth Cordell, Alison K. Esser, Vivek Sharma, Kristen Pagliai, Francesca Fontana, Jennifer L. Davis, Deborah J. Veis, Suzanne J. Bakewell, Xinming Su, Gregory M. Lanza, Katherine N. Weilbaecher, Gregory C. Fox, Christopher G. Maher, Jothilingam Sivapackiam, James A. J. Fitzpatrick, Yalin Xu, Ha X. Dang, Sheila A. Stewart
Publikováno v:
Mol Cancer Ther
Breast cancer bone metastases are common and incurable. Tumoral integrin β3 (β3) expression is induced through interaction with the bone microenvironment. Although β3 is known to promote bone colonization, its functional role during therapy of est
Autor:
Jingyu Xiang, Mijia Lu, Min Shi, Xiaogang Cheng, Kristin A. Kwakwa, Jennifer L. Davis, Xinming Su, Suzanne J. Bakewell, Yuexiu Zhang, Francesca Fontana, Yalin Xu, Deborah J. Veis, John F. DiPersio, Lee Ratner, Ralph D. Sanderson, Alessandro Noseda, Shamim Mollah, Jianrong Li, Katherine N. Weilbaecher
Publikováno v:
Journal of virology. 96(7)
The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has caused over 5 million deaths worldwide. Pneumonia and systemic inflammation contribute to its high mortality. Many viruses u
Autor:
Richard d'Arcy, Julie A. Rhoades, Jordan L. Hill, Scott A. Guelcher, Craig L. Duvall, Joseph P. Vanderburgh, Alyssa R. Merkel, Kathleen Moyer, Kristin A. Kwakwa, Sean K. Bedingfield, Sean K. Wang, Mukesh K. Gupta
Publikováno v:
ACS Nano
Breast cancer patients are at high risk for bone metastasis. Metastatic bone disease is a major clinical problem that leads to a reduction in mobility, increased risk of pathologic fracture, severe bone pain, and other skeletal-related events. The tr
Autor:
Jingyu Xiang, Wen-Chih Lee, Junyi Su, Leonel Hernandez-Aya, Jad I. Belle, Gregory M. Lanza, Christopher Egbulefu, Gregory C. Fox, Deborah J. Veis, Katherine N. Weilbaecher, Samuel Achilefu, Yalin Xu, Kristin A. Kwakwa, Xinming Su, Jennifer L. Davis, Wing Hing Wong, Helen M Tomasson, Partha Karmakar, David G. DeNardo, Melisa A Meyer, Sheila A. Stewart, Takayuki Kobayashi, Francesca Fontana, Suzanne J. Bakewell
Publikováno v:
J Clin Invest
Tumor-infiltrating myeloid cells contribute to the development of the immunosuppressive tumor microenvironment. Myeloid cell expression of arginase 1 (ARG1) promotes a protumor phenotype by inhibiting T cell function and depleting extracellular l-arg
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1c5c70c00e487c80e00926455c04cce1
https://europepmc.org/articles/PMC8516467/
https://europepmc.org/articles/PMC8516467/
Autor:
Kristin A. Kwakwa, Julie A. Sterling
Publikováno v:
Cancers, Vol 9, Iss 7, p 84 (2017)
Tumor-induced bone disease is common among patients with advanced solid cancers, especially those with breast, prostate, and lung malignancies. The tendency of these cancers to metastasize to bone and induce bone destruction is, in part, due to alter
Externí odkaz:
https://doaj.org/article/bd87e0cf7d4e4d00999993e9093eb1c0