Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Kristin A Gabor"'
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0117225 (2015)
Light microscopy enables noninvasive imaging of fluorescent species in biological specimens, but resolution is generally limited by diffraction to ~200-250 nm. Many biological processes occur on smaller length scales, highlighting the importance of t
Externí odkaz:
https://doaj.org/article/42a0773152244474826b9887087e54d9
Autor:
Kristin A Gabor, Chad R Stevens, Matthew J Pietraszewski, Travis J Gould, Juyoung Shim, Jeffrey A Yoder, Siew Hong Lam, Zhiyuan Gong, Samuel T Hess, Carol H Kim
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e68759 (2013)
Understanding spatial distribution and dynamics of receptors within unperturbed membranes is essential for elucidating their role in antiviral signaling, but conventional studies of detergent-resistant membrane fractions cannot provide this informati
Externí odkaz:
https://doaj.org/article/7a98d5813c8643c1885e625f4a9631fc
Autor:
Teminioluwa Ajayi, Prashant Rai, Min Shi, Kristin A. Gabor, Peer W. F. Karmaus, Julie M. Meacham, Kevin Katen, Jennifer H. Madenspacher, Shepherd H. Schurman, Michael B. Fessler
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract Immunity-related GTPase family M (IRGM), located on human chromosome 5q33.1, encodes a protein that promotes autophagy and suppresses the innate immune response. The minor allele of rs13361189 (−4299T>C), a single nucleotide polymorphism i
Externí odkaz:
https://doaj.org/article/e628dea807ef402180a15f40be103787
Leucine-rich repeats and calponin homology containing 4 (Lrch4) regulates the innate immune response
Autor:
Wan Chi Lin, Michael B. Fessler, Jim J. Aloor, Kathleen M. Azzam, Kristin A. Gabor, Jennifer H. Madenspacher, Artiom Gruzdev, Julie M. Lowe, David W. Draper, B. Alex Merrick, Kymberly M. Gowdy, Geoffrey A. Mueller, John Guardiola, Michael W. Henderson
Publikováno v:
Journal of Biological Chemistry. 294:1997-2008
Toll-like receptors (TLRs) are pathogen-recognition receptors that trigger the innate immune response. Recent reports have identified accessory proteins that provide essential support to TLR function through ligand delivery and receptor trafficking.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8f3e066ae4b4c1e24a499a6cfb18983
https://doi.org/10.1074/jbc.ra118.004300
https://doi.org/10.1074/jbc.ra118.004300
Autor:
Kymberly M. Gowdy, Charles E. McGee, Kristin A. Gabor, Michael B. Fessler, Brita Kilburg-Basnyat, Christopher J. Sample
Publikováno v:
Mouse Models of Innate Immunity ISBN: 9781493991662
Laboratory rodent influenza infection models have been and continue to be a critical tool for understanding virus-host interactions during infection. The incidence of seasonal influenza infections coupled with the need for novel therapeutics and univ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2123bc26360ff4f6cda312882a0f8f7
https://doi.org/10.1007/978-1-4939-9167-9_17
https://doi.org/10.1007/978-1-4939-9167-9_17
Autor:
Kathleen M. Azzam, Prashant Rai, Jennifer H. Madenspacher, Anders M. Näär, Lihua Lai, Jim J. Aloor, Michael B. Fessler, Julie M. Lowe, Wan Chi Lin, John S. Parks, Kristin A. Gabor
Publikováno v:
Journal of Biological Chemistry. 291:19651-19660
MicroRNAs (miRNAs) are short non-coding RNAs that regulate gene expression by promoting degradation and/or repressing translation of specific target mRNAs. Several miRNAs have been identified that regulate the amplitude of the innate immune response
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c8d8301c696c593e4002002f7e22c5d
https://doi.org/10.1074/jbc.m116.723056
https://doi.org/10.1074/jbc.m116.723056
Autor:
Jim J. Aloor, Michael B. Fessler, John S. Parks, Kenneth B. Tomer, Saiful M. Chowdhury, Kezia A. Addo, Kristin A. Gabor, Kathleen M. Azzam, Xuewei Zhu, William Ge
Publikováno v:
Molecular & Cellular Proteomics. 14:1859-1870
Lipid raft membrane microdomains organize signaling by many prototypical receptors, including the Toll-like receptors (TLRs) of the innate immune system. Raft-localization of proteins is widely thought to be regulated by raft cholesterol levels, but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::401e78969f9e3a2f8d57dc7dd97147f4
https://doi.org/10.1074/mcp.m114.045179
https://doi.org/10.1074/mcp.m114.045179
Autor:
Jennifer H. Madenspacher, Michael B. Fessler, Kymberly M. Gowdy, Kyathanahalli S. Janardhan, Jim J. Aloor, Kathleen M. Azzam, Kristin A. Gabor
Publikováno v:
Mucosal immunology
Scavenger receptor B-I (SR-BI) is a multirecognition receptor that regulates cholesterol trafficking and cardiovascular inflammation. Although it is expressed by neutrophils (PMNs) and lung-resident cells, no role for SR-BI has been defined in pulmon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::209060ad97e3d8efa42bb7010469fc0b
https://doi.org/10.1038/mi.2014.88
https://doi.org/10.1038/mi.2014.88
Autor:
Jacob R. Longfellow, Con Sullivan, Denise Jurcyzszak, Michelle F. Goody, Paul J. Millard, Kristin A. Gabor, Carol H. Kim
Publikováno v:
Journal of visualized experiments : JoVE. (119)
Each year, seasonal influenza outbreaks profoundly affect societies worldwide. In spite of global efforts, influenza remains an intractable healthcare burden. The principle strategy to curtail infections is yearly vaccination. In individuals who have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ca00c7ab1dd281e2ec49a43d77bddfd
https://pubmed.ncbi.nlm.nih.gov/28190053
https://pubmed.ncbi.nlm.nih.gov/28190053
Autor:
D Jurczyszak, Kristin A. Gabor, Paul J. Millard, Con Sullivan, Molly A. Matty, Carol H. Kim, David M. Tobin
In recent years, the zebrafish (Danio rerio) has developed as an important alternative to mammalian models for the study of hostpathogen interactions. Because they lack a functional adaptive immune response during the first 4-6weeks of development, z
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::20c286db81d02b5b190e5144a6c4175e
https://doi.org/10.1016/bs.mcb.2016.10.005
https://doi.org/10.1016/bs.mcb.2016.10.005