Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Kristin Ollis"'
Autor:
Jay DaRe, Serge H. Boyer, Timothy J. Colby, Paul D. van Poelje, Mark D. Erion, Kristin Ollis, William Craigo, Zhili Sun, Michael C Matelich, Jorge E. Gomez-Galeno, James M. Fujitaki, K. Raja Reddy, Bheemarao G Ugarkar
Publikováno v:
Journal of medicinal chemistry. 51(3)
Adefovir dipivoxil, a marketed drug for the treatment of hepatitis B, is dosed at submaximally efficacious doses because of renal toxicity. In an effort to improve the therapeutic index of adefovir, 1-aryl-1,3-propanyl prodrugs were synthesized with
Autor:
Serge H. Boyer, Mark D. Erion, Bheemarao G. Ugarkar, Joel Solbach, Rohan Mendonca, Joseph J. Kopcho, Atsushi Nagahisa, and James B. Wiesner, Michael C. Matelich, Megumi Tsuchiya, Kristin Ollis, Jorge Gomez-Galeno, Masami Nakane
Publikováno v:
Journal of medicinal chemistry. 48(20)
Adenosine is an endogenous neuromodulator that when produced in the central and the peripheral nervous systems has anticonvulsant, anti-inflammatory, and analgesic properties. However, efforts to use adenosine receptor agonists are plagued by dose-li
Autor:
Ling Qiu, Jared Kuemmerle, Han-Zhong Zhang, Sui Xiong Cai, Ben Tseng, Shailaja Kasibhatla, William Kemnitzer, Candace Crogan-Grundy, John Drewe, Kristin Ollis-Mason
Publikováno v:
Journal of medicinal chemistry. 48(16)
We have identified 5-(3-chlorothiophen-2-yl)-3-(4-trifluoromethylphenyl)-1,2,4-oxadiazole (1d) as a novel apoptosis inducer through our caspase- and cell-based high-throughput screening assay. Compound 1d has good activity against several breast and
Autor:
K. Raja Reddy, Michael C. Matelich, Bheemarao G. Ugarkar, Jorge E. Gómez-Galeno, Jay DaRe, Kristin Ollis, Zhili Sun, William Craigo, Timothy J. Colby, James M. Fujitaki, Serge H. Boyer, Paul D. van Poelje, Mark D. Erion
Publikováno v:
Journal of Medicinal Chemistry; Jan2008, Vol. 51 Issue 3, p666-676, 11p