Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Kristin, Ehrbar"'
Autor:
Brit Winnen, Markus C. Schlumberger, Bärbel Stecher, Kristin Ehrbar, Wolf-Dietrich Hardt, Iwan Duss, Andreas Müller
Publikováno v:
Proceedings of the National Academy of Sciences. 102:12548-12553
Many pathogenic and symbiotic Gram-negative bacteria employ type III secretion systems to inject “effector” proteins into eukaryotic host cells. These effectors manipulate signaling pathways to initiate symbiosis or disease. By using time-lapse m
Autor:
Wolf-Dietrich Hardt, Kristin Ehrbar
Publikováno v:
Infection, Genetics and Evolution. 5:1-9
Salmonella spp. are Gram-negative bacteria which cause infections ranging from mild, self-limiting enterocolitis to systemic (typhoid) disease. Recent work has established that the genetic makeup varies considerably between different Salmonella strai
Autor:
Kristin Ehrbar, Werner Machleidt, Andrea Friebel, Martin Aepfelbacher, Heiko Ilchmann, Wolf-Dietrich Hardt
Publikováno v:
Journal of Biological Chemistry. 276:34035-34040
The bacterial enteropathogen Salmonella typhimurium employs a specialized type III secretion system to inject toxins into host cells, which trigger signaling cascades leading to cell death in macrophages, secretion of pro-inflammatory cytokines, or r
Autor:
Kristin Ehrbar, Astrid Weissmüller, Wolf-Dietrich Hardt, Rita Prager, Helmut Tschäpe, Susanne Mirold, Holger Rüssmann
Publikováno v:
Journal of Bacteriology. 183:2348-2358
Salmonella spp. are enteropathogenic bacteria that cause diseases that range from a mild gastroenteritis to systemic infections. The type of disease is determined by the virulence characteristics of the Salmonella strain as well as by the host specie
Publikováno v:
Mycologia. 92:421-429
Publikováno v:
Molecular microbiology. 59(1)
Type III secretion systems (TTSS) are used by many Gram-negative pathogens for transporting effector proteins into eukaryotic host cells. Two modes of type III effector protein transport can be distinguished: transport into the surrounding medium (se
Autor:
Kristin, Ehrbar, Wolf-Dietrich, Hardt
Publikováno v:
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases. 5(1)
Salmonella spp. are Gram-negative bacteria which cause infections ranging from mild, self-limiting enterocolitis to systemic (typhoid) disease. Recent work has established that the genetic makeup varies considerably between different Salmonella strai
InvB is required for type III-dependent secretion of SopA in Salmonella enterica serovar Typhimurium
Publikováno v:
Journal of bacteriology. 186(4)
The Salmonella effector protein SopA is translocated into host cells via the SPI-1 type III secretion system (TTSS) and contributes to enteric disease. We found that the chaperone InvB binds to SopA and slightly stabilizes it in the bacterial cytosol
Autor:
Marcus Kremer, Manja Barthel, Siegfried Hapfelmeier, Kristin Ehrbar, Bärbel Stecher, Wolf-Dietrich Hardt
Salmonella enterica subspecies 1 serovar Typhimurium (serovar Typhimurium) induces enterocolitis in humans and cattle. The mechanisms of enteric salmonellosis have been studied most extensively in calf infection models. The previous studies establish
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cb0b665aa47a99fcc93196d4fc68f76
https://europepmc.org/articles/PMC321604/
https://europepmc.org/articles/PMC321604/
Publikováno v:
Journal of bacteriology. 185(23)
Salmonella enterica subspecies 1 serovar Typhimurium encodes a type III secretion system (TTSS) within Salmonella pathogenicity island 1 (SPI-1). This TTSS injects effector proteins into host cells to trigger invasion and inflammatory responses. Effe