Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Kristijonas Zemaitis"'
Autor:
Alexandra Bäckström, David Yudovich, Kristijonas Žemaitis, Ludvig Nilsén Falck, Agatheeswaran Subramaniam, Jonas Larsson
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract The CRISPR/Cas9 system offers enormous versatility for functional genomics but many applications have proven to be challenging in primary human cells compared to cell lines or mouse cells. Here, to establish a paradigm for multiplexed gene e
Externí odkaz:
https://doaj.org/article/4ca46008480f43b2bd6cabee9833fe94
Autor:
Kristijonas Zemaitis, Aurel Prosz, Agatheeswaran Subramaniam, Roman Galeev, Maria Jassinskaja, Jenny Hansson, Jonas Larsson
Publikováno v:
Experimental Hematology. 111:S54-S55
Autor:
Kristijonas Zemaitis, Unnur Thorsteinsdottir, Gudmundur L. Norddahl, Björn Nilsson, Nerea Ugidos Damboriena, Aitzkoa Lopez de Lapuente Portilla, Maroulio Pertesi, Jonas Larsson, Antton Lamarca Arrizabalaga, Caterina Cafaro, Vijay G. Sankaran, Gudmar Thorleifsson, Erik L. Bao, Natsumi Miharada, Parashar Dhapola, Malte Thodberg, Zain Ali, Abhishek Niroula, Divya Bali, Ludvig Ekdahl, Kari Stefansson, Göran Karlsson
Understanding how hematopoietic stem and progenitor cells (HSPCs) are regulated is of central importance for the development of new therapies for blood disorders and stem cell transplantation. To date, HSPC regulation has been extensively studied in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e03b48e7c73c7adfec34818fca32af86
https://doi.org/10.1101/2021.03.31.437808
https://doi.org/10.1101/2021.03.31.437808
Autor:
Marija Ger, Vaidotas Stankevicius, Kristijonas Zemaitis, Nadezda Dreize, Mindaugas Valius, Dalius Kuciauskas, Jonas Cicenas, Algirdas Kaupinis, Kestutis Suziedelis, Lee M. Graves
Publikováno v:
Cancers, Basel : MDPI AG, 2019, vol. 11, iss. 7, art. no. 972, p. [1-24]
Cancers
Volume 11
Issue 7
Cancers, Vol 11, Iss 7, p 972 (2019)
Cancers
Volume 11
Issue 7
Cancers, Vol 11, Iss 7, p 972 (2019)
Antitumor drug resistance remains a major challenge in cancer chemotherapy. Here we investigated the mechanism of acquired resistance to a novel anticancer agent RH1 designed to be activated in cancer cells by the NQO1 enzyme. Data show that in some
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c51fb24923ab5ee58e423a22d7598cdc
Autor:
Kristijonas Zemaitis, Jonas Larsson, Alexandra Bäckström, Agatheeswaran Subramaniam, Roman A. Zubarev, David Yudovich, Mehrnaz Safaee Talkhoncheh, Massimiliano Gaetani
Publikováno v:
Experimental Hematology. 88:S50
Numerous strategies have been proposed to facilitate the ex vivo expansion of human hematopoietic stem and progenitor cells (HSPCs) for clinical benefit using combinations of growth factors and small molecule compounds. Notably, UM171, a pyrimidoindo
Publikováno v:
Experimental Hematology. 76:S95
The hematopoietic stem cell (HSC) is arguably one of the most well studied adult stem cells, however, the regulatory mechanisms that govern HSC fate are still not fully understood. In order to identify novel genetic regulators of HSC function, we use
Autor:
Agatheeswaran Subramaniam, Carl Sandén, Larissa Moura-Castro, Kristijonas Žemaitis, Ludwig Schmiderer, Aurelie Baudet, Alexandra Bäckström, Elin Arvidsson, Simon Hultmark, Natsumi Miharada, Mattias Magnusson, Kajsa Paulsson, Thoas Fioretos, Jonas Larsson
Publikováno v:
Haematologica, Vol 107, Iss 9 (2022)
Externí odkaz:
https://doaj.org/article/e8b2e48f41564e2ebc184752db9efe54
Autor:
David Yudovich, Alexandra Bäckström, Ludwig Schmiderer, Kristijonas Žemaitis, Agatheeswaran Subramaniam, Jonas Larsson
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-11 (2020)
Abstract The CRISPR/Cas9 system is a versatile tool for functional genomics and forward genetic screens in mammalian cells. However, it has been challenging to deliver the CRISPR components to sensitive cell types, such as primary human hematopoietic
Externí odkaz:
https://doaj.org/article/37fcffdd00f84de08d81d45c0b3fdfd6