Zobrazeno 1 - 10
of 199
pro vyhledávání: '"Kristien, Boelaert"'
Autor:
Hisham Mehanna, Jonathan J Deeks, Kristien Boelaert, Gitta Madani, Paul Sidhu, Paul Nankivell, Neil Sharma, Rebecca Woolley, Judith Taylor, Tessa Fulton-Lieuw, Andrew Palmer
Publikováno v:
Health Technology Assessment, Vol 28, Iss 46 (2024)
Background Strain and shear wave elastography which is commonly used with concurrent real-time imaging known as real-time ultrasound shear/strain wave elastography is a new diagnostic technique that has been reported to be useful in the diagnosis of
Externí odkaz:
https://doaj.org/article/986143b4d54241d284f84397d22839a7
Autor:
Riazul Zannat, Jonathan Lee, Jameel Muzaffar, Martin L. Read, Katie Brookes, Neil Sharma, Kristien Boelaert, Christopher J. McCabe, Hannah R. Nieto
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2023)
IntroductionRadioactive iodine (RAI) therapy is a critical component in the post-surgical management of thyroid cancer patients, as well as being a central therapeutic option in the treatment of hyperthyroidism. Previous work suggests that antithyroi
Externí odkaz:
https://doaj.org/article/b7b8f22aaf5a4010b7313cb20ff1f991
Autor:
Krishnarajah Nirantharakumar, Kristien Boelaert, Keith R Abrams, Barbara Torlinska, Jonathan M Hazlehurst, Julia R Priestley, Samuel J Finnikin, Philip Saunders
Publikováno v:
BMJ Open, Vol 11, Iss 10 (2021)
Introduction Hyperthyroidism is a common condition affecting up to 3% of the UK population. Treatment improves symptoms and reduces the risk of atrial fibrillation and stroke that contribute to increased mortality. The most common symptom is weight l
Externí odkaz:
https://doaj.org/article/2cd6dcbbdb0f46719df000bf59fb1c24
Autor:
Alvin H. K. Karangizi, May Al-Shaghana, Sarah Logan, Sherwin Criseno, Rachel Webster, Kristien Boelaert, Peter Hewins, Lorraine Harper
Publikováno v:
BMC Nephrology, Vol 20, Iss 1, Pp 1-7 (2019)
Abstract Background Glucocorticoids (GCs) are frequently used to treat glomerular diseases but are associated with multiple adverse effects including hypothalamic-pituitary-adrenal axis inhibition that can lead to adrenal insufficiency (AI) on withdr
Externí odkaz:
https://doaj.org/article/193f28d8eef64777b7cc775c7653d507
Publikováno v:
Endocrinology and Metabolism Clinics of North America. 51:417-436
Thyroid disease is associated with adverse maternal and fetal outcomes. Appropriate reference ranges should be used for the interpretation of test results, although universal screening for thyroid dysfunction is not warranted. Overt thyroid dysfuncti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::167dd98c971bef7e83e3097337e7e96f
https://doi.org/10.1016/j.ecl.2021.12.005
https://doi.org/10.1016/j.ecl.2021.12.005
Autor:
Rima K Dhillon-Smith, Lee J Middleton, Kirandeep K Sunner, Versha Cheed, Krys Baker, Samantha Farrell-Carver, Ruth Bender-Atik, Rina Agrawal, Kalsang Bhatia, Edmond Edi-Osagie, Tarek Ghobara, Pratima Gupta, Davor Jurkovic, Yacoub Khalaf, Marjory MacLean, Chris McCabe, Khashia Mulbagal, Natalie Nunes, Caroline Overton, Siobhan Quenby, Rajendra Rai, Nick Raine-Fenning, Lynne Robinson, Jackie Ross, Andrew Sizer, Rachel Small, Alex Tan, Martyn Underwood, Mark D Kilby, Kristien Boelaert, Jane Daniels, Shakila Thangaratinam, Shiao-Yng Chan, Arri Coomarasamy
Publikováno v:
Efficacy and Mechanism Evaluation, Vol 6, Iss 11 (2019)
Background: Thyroid autoantibodies, specifically thyroid peroxidase antibodies, have been associated with miscarriage and pre-term birth in women with a normal thyroid function. Small randomised controlled trials have found that treatment with levoth
Externí odkaz:
https://doaj.org/article/7ee8dadd8bfb411bbd74d15c717afed3
Autor:
Martin L. Read, Katie Brookes, Ling Zha, Selvambigai Manivannan, Jana Kim, Merve Kocbiyik, Alice Fletcher, Caroline M. Gorvin, George Firth, Gilbert O. Fruhwirth, Juan P. Nicola, Sissy Jhiang, Matthew D. Ringel, Moray J. Campbell, Kavitha Sunassee, Philip J. Blower, Kristien Boelaert, Hannah R. Nieto, Vicki E. Smith, Christopher J. McCabe
The sodium/iodide symporter (NIS) frequently shows diminished plasma membrane (PM) targeting in differentiated thyroid cancer (DTC), resulting in suboptimal radioiodide (RAI) treatment and poor prognosis. The mechanisms which govern the endocytosis o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e0a757baf79e22f16a69b80be8a04fd2
https://doi.org/10.1101/2023.05.22.541733
https://doi.org/10.1101/2023.05.22.541733
Autor:
Kiran Issuree, Kristien Boelaert
Publikováno v:
Endocrine Abstracts.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb86cd1999fa7404f4497e2006bd7596
https://doi.org/10.1530/endoabs.91.wc11
https://doi.org/10.1530/endoabs.91.wc11
Autor:
Christopher J. McCabe, Vicki E. Smith, Andrew S. Turnell, Kristien Boelaert, Moray J. Campbell, James A. Fagin, Iñigo Landa, Gareth G. Lavery, Rebecca J. Thompson, Mohammed Alshahrani, Hannah R. Nieto, Katie Brookes, Vikki L. Poole, Dean P. Larner, Caitlin E.M. Thornton, Martin L. Read, Alice Fletcher
The sodium iodide symporter (NIS) is required for iodide uptake, which facilitates thyroid hormone biosynthesis. NIS has been exploited for over 75 years in ablative radioiodine (RAI) treatment of thyroid cancer, where its ability to transport radioi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db5ac66f1269b400c2f72c32eb709142
https://doi.org/10.1158/0008-5472.c.6511641.v1
https://doi.org/10.1158/0008-5472.c.6511641.v1
Autor:
Christopher J. McCabe, Vicki E. Smith, Andrew S. Turnell, Kristien Boelaert, Moray J. Campbell, James A. Fagin, Iñigo Landa, Gareth G. Lavery, Rebecca J. Thompson, Mohammed Alshahrani, Hannah R. Nieto, Katie Brookes, Vikki L. Poole, Dean P. Larner, Caitlin E.M. Thornton, Martin L. Read, Alice Fletcher
Significant co-localization and trafficking of ARF4-dsRED and NIS-GFP proteins in co-incident vesicles at the plasma membrane in HeLa cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bccf7fbfad38afb0c38830b1ca44f6ef
https://doi.org/10.1158/0008-5472.22423998
https://doi.org/10.1158/0008-5472.22423998