Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Kristie Sykes"'
Autor:
Daniel P. Zimmer, Courtney M. Shea, Jenny V. Tobin, Boris Tchernychev, Peter Germano, Kristie Sykes, Ali R. Banijamali, Sarah Jacobson, Sylvie G. Bernier, Renee Sarno, Andrew Carvalho, Yueh-tyng Chien, Regina Graul, Emmanuel S. Buys, Juli E. Jones, James D. Wakefield, Gavrielle M. Price, Jennifer G. Chickering, G. Todd Milne, Mark G. Currie, Jaime L. Masferrer
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Nitric oxide (NO)-soluble guanylate cyclase (sGC)-cyclic 3',5' GMP (cGMP) signaling plays a central role in regulation of diverse processes including smooth muscle relaxation, inflammation, and fibrosis. sGC is activated by the short-lived physiologi
Externí odkaz:
https://doaj.org/article/e994be112c3a40db87031271143e9556
Autor:
Sarah Jacobson, Jenny Tobin, Renee Sarno, Jaime L. Masferrer, Andrew Carvalho, Boris Tchernychev, Yueh-Tyng Chien, G. Todd Milne, Jennifer G. Chickering, Peter Germano, Ali R. Banijamali, Gavrielle M Price, Emmanuel S. Buys, James Wakefield, Regina Graul, Juli E. Jones, Courtney Shea, Sylvie G. Bernier, Daniel P. Zimmer, Kristie Sykes, Mark G. Currie
Publikováno v:
Frontiers in Pharmacology
Frontiers in Pharmacology, Vol 11 (2020)
Frontiers in Pharmacology, Vol 11 (2020)
Nitric oxide (NO)-soluble guanylate cyclase (sGC)-cyclic 3',5' GMP (cGMP) signaling plays a central role in regulation of diverse processes including smooth muscle relaxation, inflammation, and fibrosis. sGC is activated by the short-lived physiologi
Autor:
Joel D. Moore, Kristie Sykes, Peter Germano, Kimberly Long, Jenny Tobin, Jaime L. Masferrer, Robert Jefferson, Erik Solberg, James E. Sheppeck, Takashi Nakai, Samuel Rivers, Courtney Shea, James Wakefield
Publikováno v:
The FASEB Journal. 29
Soluble guanylate cyclase (sGC) stimulators have the potential to treat a variety of cardiovascular diseases via the nitric oxide (NO)-sGC-cyclic guanosine monophosphate (cGMP) pathway. Ironwood Ph...
Autor:
Peter Germano, G-Yoon Jamie Im, Maria D. Ribadeneira, Jenny Tobin, James Wakefield, Adaline Smith, Kristie Sykes, Jaime L. Masferrer, James E. Sheppeck, Samuel Rivers, Courtney Shea, Robert Jefferson
Publikováno v:
BMC Pharmacology & Toxicology
Background Soluble guanylate cyclase (sGC) stimulators demonstrate smooth muscle relaxation and vasodilation via the nitric oxide (NO)-sGC-cyclic guanosine monophosphate (cGMP) pathway. A novel class of sGC stimulators, the pyrazole-pyrimidines, was
Autor:
Maria Mayorga, Thea Norman, Iverson Sara, Daniel P. Zimmer, Toby Feibelman, Joshua Trueheart, Jenny Tobin, Kevin T. Madden, Douglas Holtzman, Alex W. Monreal, Manor Askenazi, Edward M. Driggers, Mary Maxon, Paul Blomquist, Kristie Sykes, John Royer, Sofie R. Salama, Martinez Eduardo J, Mary-Ellen Boers, Etchell Cordero
Publikováno v:
Nature biotechnology. 21(2)
We describe a method to decipher the complex inter-relationships between metabolite production trends and gene expression events, and show how information gleaned from such studies can be applied to yield improved production strains. Genomic fragment