Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Kristiana Xhima"'
Autor:
Kristiana Xhima, Isabelle Aubert
Publikováno v:
Neural Regeneration Research, Vol 16, Iss 9, Pp 1783-1785 (2021)
Externí odkaz:
https://doaj.org/article/718a284395514481a3eb63c5d2b376ea
Autor:
Kristiana Xhima, Dallan McMahon, Edward Ntiri, Maged Goubran, Kullervo Hynynen, Isabelle Aubert
Publikováno v:
Bio-Protocol, Vol 11, Iss 12 (2021)
Basal forebrain cholinergic neurons (BFCNs) regulate circuit dynamics underlying cognitive processing, including attention, memory, and cognitive flexibility. In Alzheimer’s disease and related neurodegenerative conditions, the degeneration of BFCN
Externí odkaz:
https://doaj.org/article/4a4a04cac8e143fa89ad584a76da773c
Autor:
Reaz Vawda, Anna Badner, James Hong, Mirriam Mikhail, Alam Lakhani, Rachel Dragas, Kristiana Xhima, Tanya Barretto, Clifford L. Librach, Michael G. Fehlings
Publikováno v:
Stem Cells Translational Medicine, Vol 8, Iss 7, Pp 639-649 (2019)
Abstract Localized vascular disruption after traumatic spinal cord injury (SCI) triggers a cascade of secondary events, including inflammation, gliosis, and scarring, that can further impact recovery. In addition to immunomodulatory and neurotrophic
Externí odkaz:
https://doaj.org/article/3c110a62146d427ba5be84304e34db3b
Efficacy of gene delivery to the brain using AAV and ultrasound depends on serotypes and brain areas
Autor:
Rikke Hahn Kofoed, Chinaza Lilian Dibia, Kate Noseworthy, Kristiana Xhima, Nathalie Vacaresse, Kullervo Hynynen, Isabelle Aubert
Publikováno v:
Journal of controlled release : official journal of the Controlled Release Society. 351
Focused ultrasound combined with intravenously injected microbubbles (FUS) is known to non-invasively, locally, and transiently increase the permeability of the blood-brain barrier (BBB). A promising approach for non-invasive gene delivery to the bra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a4ba0af23b7406a383e57c306b6185bb
https://pubmed.ncbi.nlm.nih.gov/36179767
https://pubmed.ncbi.nlm.nih.gov/36179767
Autor:
Alejandro Jose, Anna Badner, Michael G. Fehlings, Kristiana Xhima, Mirriam Mikhail, James Hong, Rachel Dragas, Reaz Vawda
Publikováno v:
Stem Cells and Development
Cell therapy offers significant promise for traumatic spinal cord injury (SCI), which despite many medical advances, has limited treatment strategies. Able to address the multifactorial and dynamic pathophysiology of SCI, cells present various advant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2238b802aad3511c210c524f1ef64ab
https://doi.org/10.1089/scd.2020.0079
https://doi.org/10.1089/scd.2020.0079
Autor:
Joel C. Watts, Rikke Hahn Kofoed, Fadl Nabbouh, S. Pablo Sardi, Paul E. Fraser, Tammy Langman, Anurag Tandon, Yasmeen Al-Fahoum, Kristiana Xhima, Lamya S. Shihabuddin, Sindhu Menon, Isabelle Aubert, Howard T.J. Mount
Publikováno v:
Brain Communications
The accumulation of aggregated alpha-synuclein (α-syn) in Parkinson's disease, dementia with Lewy bodies and multiple system atrophy is thought to involve a common prion-like mechanism, whereby misfolded α-syn provides a conformational template for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfc6005e2483488ec72729d31109d102
https://doi.org/10.1093/braincomms/fcab247
https://doi.org/10.1093/braincomms/fcab247
Autor:
Mirriam Mikhail, Michael G. Fehlings, Tanya Barretto, Alam Lakhani, Clifford Librach, Rachel Dragas, Anna Badner, James Hong, Kristiana Xhima, Reaz Vawda
Publikováno v:
Stem Cells Translational Medicine, Vol 8, Iss 7, Pp 639-649 (2019)
Stem Cells Translational Medicine
Stem Cells Translational Medicine
Localized vascular disruption after traumatic spinal cord injury (SCI) triggers a cascade of secondary events, including inflammation, gliosis, and scarring, that can further impact recovery. In addition to immunomodulatory and neurotrophic propertie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecae59af76a8f61edcff20600c72d861
https://doaj.org/article/3c110a62146d427ba5be84304e34db3b
https://doaj.org/article/3c110a62146d427ba5be84304e34db3b
Publikováno v:
Brain Plasticity
Physical activity plays an essential role in maintaining a healthy body, yet it also provides unique benefits for the vascular and cellular systems that sustain a healthy brain. While the benefit of exercise has been observed in humans of all ages, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe2244b609fec1864b1c4ad0b889e0a8
https://doi.org/10.3233/bpl-180069
https://doi.org/10.3233/bpl-180069
Autor:
Kristiana Xhima, Kelly Markham-Coultes, Rikke Hahn Kofoed, H Uri Saragovi, Kullervo Hynynen, Isabelle Aubert
Publikováno v:
Xhima, K, Markham-Coultes, K, Kofoed, R H, Saragovi, H U, Hynynen, K & Aubert, I 2022, ' Ultrasound delivery of a TrkA agonist confers neuroprotection to Alzheimer-associated pathologies ', Brain, vol. 145, no. 8, pp. 2806-2822 .
Early degeneration of basal forebrain cholinergic neurons contributes substantially to cognitive decline in Alzheimer’s disease. Evidence from preclinical models of neuronal injury and aging support a pivotal role for nerve growth factor (NGF) in n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::addd83d2a55840d293bb2da54784f60a
https://pubmed.ncbi.nlm.nih.gov/34919633
https://pubmed.ncbi.nlm.nih.gov/34919633
Autor:
Dallan McMahon, Kristiana Xhima, Kullervo Hynynen, Maged Goubran, Emmanuel E. Ntiri, Isabelle Aubert
Publikováno v:
Bio Protoc
Basal forebrain cholinergic neurons (BFCNs) regulate circuit dynamics underlying cognitive processing, including attention, memory, and cognitive flexibility. In Alzheimer's disease and related neurodegenerative conditions, the degeneration of BFCNs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76f64badcdb79db827f9d21b5c717db1
https://pubmed.ncbi.nlm.nih.gov/34262999
https://pubmed.ncbi.nlm.nih.gov/34262999