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of 4
pro vyhledávání: '"Kristian Teichert"'
Pathogenic BCL11A variants provide insights into the mechanisms of human fetal hemoglobin silencing.
Autor:
Yong Shen, Rick Li, Kristian Teichert, Kara E Montbleau, Jeffrey M Verboon, Richard A Voit, Vijay G Sankaran
Publikováno v:
PLoS Genetics, Vol 17, Iss 10, p e1009835 (2021)
Increased production of fetal hemoglobin (HbF) can ameliorate the severity of sickle cell disease and β-thalassemia. BCL11A has been identified as a key regulator of HbF silencing, although its precise mechanisms of action remain incompletely unders
Externí odkaz:
https://doaj.org/article/16c4ace60f69490ea3d73aa1074950f0
Autor:
Richard A. Voit, Liming Tao, Fulong Yu, Liam D. Cato, Blake Cohen, Travis J. Fleming, Mateusz Antoszewski, Xiaotian Liao, Claudia Fiorini, Satish K. Nandakumar, Lara Wahlster, Kristian Teichert, Aviv Regev, Vijay G. Sankaran
Publikováno v:
Nature immunology.
The molecular regulation of human hematopoietic stem cell (HSC) maintenance is therapeutically important, but limitations in experimental systems and interspecies variation have constrained our knowledge of this process. Here, we have studied a rare
Autor:
Richard A. Voit, Liming Tao, Fulong Yu, Liam D. Cato, Blake Cohen, Xiaotian Liao, Claudia Fiorini, Satish K. Nandakumar, Lara Wahlster, Kristian Teichert, Aviv Regev, Vijay G. Sankaran
The molecular regulation of human hematopoietic stem cell (HSC) self-renewal and maintenance is of substantial interest, but limitations in experimental systems and interspecies variation have constrained our knowledge of this process. To better disc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee19c02c5492fa70049e6ea738e324ed
https://doi.org/10.1101/2021.12.09.471942
https://doi.org/10.1101/2021.12.09.471942
Autor:
Roxana E. Iacob, James E. Bradner, Kristian Teichert, Roodolph St. Pierre, John R. Engen, Sixun Chen, Joshiawa Paulk, Mette Ishoey
Publikováno v:
The FASEB Journal. 29
The nuclear SET domain containing protein (NSD) family of histone methyltransferases is an oncogenic family of proteins, whose overexpression is directly involved in cancers, such as acute lymphobl...