Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Kristian Reckzeh"'
Autor:
Sophia Engelhard, Montserrat Estruch, Shuyu Qin, Christoph A. Engelhard, Francisco G. Rodriguez-Gonzalez, Martine Drilsvik, Javier Martin-Gonzalez, Jeng-Wei Lu, David Bryder, Claus Nerlov, Joachim Weischenfeldt, Kristian Reckzeh, Kim Theilgaard-Mönch
Publikováno v:
Cell Reports, Vol 43, Iss 7, Pp 114475- (2024)
Summary: Endomucin (EMCN) currently represents the only hematopoietic stem cell (HSC) marker expressed by both murine and human HSCs. Here, we report that EMCN+ long-term repopulating HSCs (LT-HSCs; CD150+CD48−LSK) have a higher long-term multi-lin
Externí odkaz:
https://doaj.org/article/3dfc405563e042acaabd1378d8d20651
Autor:
Kim Theilgaard-Mönch, Sachin Pundhir, Kristian Reckzeh, Jinyu Su, Marta Tapia, Benjamin Furtwängler, Johan Jendholm, Janus Schou Jakobsen, Marie Sigurd Hasemann, Kasper Jermiin Knudsen, Jack Bernard Cowland, Anna Fossum, Erwin Schoof, Mikkel Bruhn Schuster, Bo T. Porse
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-17 (2022)
Here the authors show that differentiation of haematopoietic stem cells into mature blood cells is primed by cell type-specific transcription factors at the enhancer level during early differentiation, before they confere promoter-driven growth arres
Externí odkaz:
https://doaj.org/article/c8be37de68644952b82321d25c3ff0a5
Autor:
Kristian Reckzeh, Hüsün Kizilkaya, Alexandra Søgaard Helbo, Montserrat Estruch Alrich, André Gundersen Deslauriers, Amit Grover, Nicolas Rapin, Fazila Asmar, Kirsten Grønbæk, Bo Porse, Niels Borregaard, Dietmar Vestweber, Claus Nerlov, Kim Theilgaard-Mönch
Publikováno v:
Blood Advances, Vol 2, Iss 13, Pp 1628-1632 (2018)
Externí odkaz:
https://doaj.org/article/2f66945dee264ca7845692de80ef5b07
Autor:
Göran Karlsson, Emma Rörby, Cristina Pina, Shamit Soneji, Kristian Reckzeh, Kenichi Miharada, Christine Karlsson, Yanping Guo, Cristina Fugazza, Rajeev Gupta, Joost H.A. Martens, Hendrik G. Stunnenberg, Stefan Karlsson, Tariq Enver
Publikováno v:
Cell Reports, Vol 4, Iss 4, Pp 642-648 (2013)
Prospective isolation is critical for understanding the cellular and molecular aspects of stem cell heterogeneity. Here, we identify the cell surface antigen CD9 as a positive marker that provides a simple alternative for hematopoietic stem cell isol
Externí odkaz:
https://doaj.org/article/c646fa2864cd42d88a3c00c00c5a9d15
Autor:
K. Theilgaard-Mönch, S. Pundhir, K. Kristian Reckzeh, J. Su, M. Tapia, B. Furtwängler, J. Jendholm, J. Schou Jakobsen
Publikováno v:
HemaSphere, Vol 6, Pp 1297-1298 (2022)
Externí odkaz:
https://doaj.org/article/2725d1dcd9da475aa004f1f3cf955f18
Autor:
Kim Theilgaard-Mönch, Thomas Helleday, Ulrika Warpman Berglund, Sophia Engelhard, Camilla Vittori, Kumar Sanjiv, Kristian Reckzeh, Montserrat Estruch, Anders Centio
Currently, the majority of patients with acute myeloid leukemia (AML) still die of their disease due to primary resistance or relapse toward conventional reactive oxygen species (ROS)- and DNA damage–inducing chemotherapy regimens. Herein, we explo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d214d6aedb84973092fd78ecb7c18fe
https://doi.org/10.1158/1535-7163.c.6543309
https://doi.org/10.1158/1535-7163.c.6543309
Autor:
Kim Theilgaard-Mönch, Thomas Helleday, Ulrika Warpman Berglund, Sophia Engelhard, Camilla Vittori, Kumar Sanjiv, Kristian Reckzeh, Montserrat Estruch, Anders Centio
Supplementary Figure from Inhibition of Oxidized Nucleotide Sanitation By TH1579 and Conventional Chemotherapy Cooperatively Enhance Oxidative DNA Damage and Survival in AML
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05d2b851cc283c27330d8dc9028e56f9
https://doi.org/10.1158/1535-7163.22522218.v1
https://doi.org/10.1158/1535-7163.22522218.v1
Autor:
Jesper V. Olsen, Lars J. Jensen, Kim Theilgaard-Mönch, Stephen C. Blacklow, Vidyasiri Vemulapalli, Kristian Reckzeh, Ilaria Piga, Marie Locard-Paulet, Giulia Franciosa, Anamarija Pfeiffer
Supplementary Data from Phosphorylation of SHP2 at Tyr62 Enables Acquired Resistance to SHP2 Allosteric Inhibitors in FLT3-ITD–Driven AML
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e44e4fc3515e4df0e347ed1a54c643c
https://doi.org/10.1158/0008-5472.22430284
https://doi.org/10.1158/0008-5472.22430284
Autor:
Jesper V. Olsen, Lars J. Jensen, Kim Theilgaard-Mönch, Stephen C. Blacklow, Vidyasiri Vemulapalli, Kristian Reckzeh, Ilaria Piga, Marie Locard-Paulet, Giulia Franciosa, Anamarija Pfeiffer
The protein tyrosine phosphatase SHP2 is crucial for oncogenic transformation of acute myeloid leukemia (AML) cells expressing mutated receptor tyrosine kinases. SHP2 is required for full RAS-ERK activation to promote cell proliferation and survival
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::78e5a2bf99c8efb8cfecfca5df859849
https://doi.org/10.1158/0008-5472.c.6513577.v1
https://doi.org/10.1158/0008-5472.c.6513577.v1
Autor:
Jesper V. Olsen, Lars J. Jensen, Kim Theilgaard-Mönch, Stephen C. Blacklow, Vidyasiri Vemulapalli, Kristian Reckzeh, Ilaria Piga, Marie Locard-Paulet, Giulia Franciosa, Anamarija Pfeiffer
Supplementary Table from Phosphorylation of SHP2 at Tyr62 Enables Acquired Resistance to SHP2 Allosteric Inhibitors in FLT3-ITD–Driven AML
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3670270ef0f89fb2bad014be2a715886
https://doi.org/10.1158/0008-5472.22430254.v1
https://doi.org/10.1158/0008-5472.22430254.v1