Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Kristian Otkjær"'
Publikováno v:
Dermatology Reports, Vol 2, Iss 2, Pp e14-e14 (2010)
14-3-3 is a highly conserved protein involved in a number of cellular processes including cell signalling, cell cycle regulation and gene transcription. Seven isoforms of the protein have been identified; β, γ, ε, ζ, η, σ and τ. The expression
Externí odkaz:
https://doaj.org/article/7392122b7fd44096b26ec7397a5514c6
Autor:
Kristian Otkjaer, Helmut Holtmann, Tue Wenzel Kragstrup, Søren Riis Paludan, Claus Johansen, Matthias Gaestel, Knud Kragballe, Lars Iversen
Publikováno v:
PLoS ONE, Vol 5, Iss 1, p e8671 (2010)
IL-24 (melanoma differentiation-associated gene-7 (mda-7)), a member of the IL-10 cytokine family, possesses the properties of a classical cytokine as well as tumor suppressor effects. The exact role of IL-24 in the immune system has not been defined
Externí odkaz:
https://doaj.org/article/86923dfdec6d49cebf0bca179fe024e3
Autor:
Knud Kragballe, Carina A. Rosenberg, Søren R. Paludan, Claus Johansen, Lars Iversen, Mogens Erlandsen, Thomas Vorup-Jensen, Rikke Bech, Babak Jalilian, Ralf Agger, Kristian Otkjaer
Publikováno v:
Bech, R, Jalilian, B, Agger, R, Iversen, L, Erlandsen, M, Otkjaer, K, Johansen, C, Paludan, S R, Rosenberg, C A, Kragballe, K & Vorup-Jensen, T 2016, ' Interleukin 20 regulates dendritic cell migration and expression of co-stimulatory molecules ', Molecular and Cellular Therapies, vol. 4, no. 1 . https://doi.org/10.1186/s40591-016-0046-x
Bech, R, Jalilian, B, Agger, R, Iversen, L, Erlandsen, M, Otkjaer, K, Johansen, C, Paludan, S R, Rosenberg, C A, Kragballe, K & Vorup-Jensen, T 2016, ' Interleukin 20 regulates dendritic cell migration and expression of co-stimulatory molecules ', Molecular and Cellular Therapies, vol. 4, 1 . https://doi.org/10.1186/s40591-016-0046-x
Molecular and Cellular Therapies
Bech, R, Jalilian, B, Agger, R, Iversen, L, Erlandsen, M, Otkjaer, K, Johansen, C, Paludan, S R, Rosenberg, C A, Kragballe, K & Vorup-Jensen, T 2016, ' Interleukin 20 regulates dendritic cell migration and expression of co-stimulatory molecules ', Molecular and Cellular Therapies, vol. 4, 1 . https://doi.org/10.1186/s40591-016-0046-x
Molecular and Cellular Therapies
Background Psoriasis is an inflammatory disease characterized by leukocyte skin infiltration. Interestingly, recent works suggest that the migration of dendritic cells (DCs) is abnormal in psoriatic skin. DCs have significant role in regulating the f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a6dc3e54ebdef379123238ef2270999
https://pure.au.dk/portal/da/publications/interleukin-20-regulates-dendritic-cell-migration-and-expression-of-costimulatory-molecules(0084d84f-af25-4c56-b9e3-56761d43c121).html
https://pure.au.dk/portal/da/publications/interleukin-20-regulates-dendritic-cell-migration-and-expression-of-costimulatory-molecules(0084d84f-af25-4c56-b9e3-56761d43c121).html
Autor:
Jens S. Andersen, Esben N. Flindt, Karsten Kristiansen, Lene Aarenstrup, Morten Kirkegaard, Kristian Otkjaer
Publikováno v:
Aarenstrup, L, Flindt, E N, Otkjaer, K, Kirkegaard, M, Andersen, J S & Kristiansen, K 2008, ' HDAC Activity Is Required for p65/RelA-Dependent Repression of PPARdelta-Mediated Transactivation in Human Keratinocytes ', Journal of Investigative Dermatology, vol. 128, pp. 1095-1106 . https://doi.org/10.1038/sj.jid.5701146
Aarenstrup, L, Flindt, E N, Otkjaer, K, Kirkegaard, M, Andersen, J S & Kristiansen, K 2007, ' HDAC activity is required for p65/RelA-dependent repression of PPARdelta-mediated transactivation in human keratinocytes ', Journal of Investigative Dermatology, vol. 128, no. 5, pp. 1095-106 . https://doi.org/10.1038/sj.jid.5701146
Aarenstrup, L, Flindt, E N, Otkjaer, K, Kirkegaard, M, Andersen, J S & Kristiansen, K 2007, ' HDAC activity is required for p65/RelA-dependent repression of PPARdelta-mediated transactivation in human keratinocytes ', Journal of Investigative Dermatology, vol. 128, no. 5, pp. 1095-106 . https://doi.org/10.1038/sj.jid.5701146
Peroxisome proliferator-activated receptors (PPARs) play a key role in differentiation, inflammation, migration, and survival of epidermal keratinocytes. The NF-kappaB has long been known to play pivotal roles in immune and inflammatory responses, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60f4ef1bd7cad268faad7c164c88e4e0
https://doi.org/10.1038/sj.jid.5701146
https://doi.org/10.1038/sj.jid.5701146
Autor:
Hans Lomholt, Jens Madsen, Torben Steiniche, Kristian Otkjaer, Ole Haagen Nielsen, Uffe Holmskov, Christian Vestergaard, Thomas Hohwy, Gritt Søerensen
Publikováno v:
University of Southern Denmark
Hohwy, T, Otkjaer, K, Madsen, J, Søerensen, G, Vestergaard, C, Steiniche, T, Holmskov, U, Lomholt, H & Nielsen, O 2006, ' Surfactant protein D in atopic dermatitis and psoriasis ', Experimental Dermatology, vol. 15, no. 3, pp. 168-74 . https://doi.org/10.1111/j.1600-0625.2006.00406.x
Hohwy, T, Otkjaer, K, Madsen, J, Sørensen, G L, Nielsen, O, Vestergaard, C, Steiniche, T, Holmskov, U & Lomholt, H 2006, ' Surfactant protein D in atopic dermatitis and psoriasis ', Experimental Dermatology, vol. 15, no. 3, pp. 168-174 .
Hohwy, T, Otkjaer, K, Madsen, J, Søerensen, G, Vestergaard, C, Steiniche, T, Holmskov, U, Lomholt, H & Nielsen, O 2006, ' Surfactant protein D in atopic dermatitis and psoriasis ', Experimental Dermatology, vol. 15, no. 3, pp. 168-74 . https://doi.org/10.1111/j.1600-0625.2006.00406.x
Hohwy, T, Otkjaer, K, Madsen, J, Sørensen, G L, Nielsen, O, Vestergaard, C, Steiniche, T, Holmskov, U & Lomholt, H 2006, ' Surfactant protein D in atopic dermatitis and psoriasis ', Experimental Dermatology, vol. 15, no. 3, pp. 168-174 .
Udgivelsesdato: marts 2006 The collectin surfactant protein-D (SP-D) shows antimicrobial and immuno-regulatory properties and has recently been detected in the basal layers of normal human skin. This molecule potentially plays an important role in in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::494061f5ec17726caabe0bdf7a39f73f
https://doi.org/10.1111/j.1600-0625.2006.00406.x
https://doi.org/10.1111/j.1600-0625.2006.00406.x
Autor:
Kristian Otkjaer, Claus Johansen, Lars Iversen, John Rømer, Rikke Bech, Ralf Agger, Knud Kragballe, Thomas Vorup-Jensen, Svend Birkelund
Publikováno v:
Bech, R, Otkjaer, K, Birkelund, S, Vorup-Jensen, T, Agger, R, Johansen, C, Iversen, L, Kragballe, K & Rømer, J 2014, ' Interleukin 20 protein locates to distinct mononuclear cells in psoriatic skin ', Experimental Dermatology, vol. 23, no. 5, pp. 349–351 . https://doi.org/10.1111/exd.12371
Bech, R, Otkjaer, K, Birkelund, S, Vorup-Jensen, T, Agger, R, Johansen, C, Iversen, L, Kragballe, K & Rømer, J 2014, ' Interleukin 20 protein locates to distinct mononuclear cells in psoriatic skin ', Experimental Dermatology Online . https://doi.org/10.1111/exd.12371
Bech, R, Otkjaer, K, Birkelund, S, Vorup-Jensen, T, Agger, R, Johansen, C, Iversen, L, Kragballe, K & Rømer, J 2014, ' Interleukin 20 protein locates to distinct mononuclear cells in psoriatic skin ', Experimental Dermatology Online . https://doi.org/10.1111/exd.12371
We previously demonstrated that mRNA for the pro-inflammatory cytokine interleukin 20 (IL-20) is expressed in suprapapillary keratinocytes of lesional psoriatic skin. Here, we describe the distribution of IL-20 protein and the identity of the IL-20-p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffd2422759e5f2fb37d0f3d877b0d316
https://vbn.aau.dk/da/publications/44e17955-4e2a-417c-8879-64391df6d4e8
https://vbn.aau.dk/da/publications/44e17955-4e2a-417c-8879-64391df6d4e8
Publikováno v:
Dermatology Reports
Raaby, L, Otkjær, K, Salvskov-Iversen, M L, Johansen, C & Iversen, L 2010, ' A Characterization of the expression of 14-3-3 isoforms in psoriasis, basal cell carcinoma, atopic dermatitis and contact dermatitis ', Dermatology Reports, vol. 2, no. 2, pp. 36-41 . https://doi.org/10.4081/dr.2010.e14
Dermatology Reports, Vol 2, Iss 2, Pp e14-e14 (2010)
Raaby, L, Otkjær, K, Salvskov-Iversen, M L, Johansen, C & Iversen, L 2010, ' A Characterization of the expression of 14-3-3 isoforms in psoriasis, basal cell carcinoma, atopic dermatitis and contact dermatitis ', Dermatology Reports, vol. 2, no. 2, pp. 36-41 . https://doi.org/10.4081/dr.2010.e14
Dermatology Reports, Vol 2, Iss 2, Pp e14-e14 (2010)
14-3-3 is a highly conserved protein involved in a number of cellular processes including cell signalling, cell cycle regulation and gene transcription. Seven isoforms of the protein have been identified; β, γ, ε, ζ, η, σ and τ. The expression
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed8034fec9d7dfc92eebf3da76dd5bed
https://pubmed.ncbi.nlm.nih.gov/25386251
https://pubmed.ncbi.nlm.nih.gov/25386251
Autor:
Knud Kragballe, Claus Johansen, Lars Iversen, Jette Lindorff Riis, Christian Vestergaard, Kristian Otkjaer
Publikováno v:
Riis, J L, Johansen, C, Vestergaard, C, Otkjaer, K, Kragballe, K & Iversen, L 2011, ' CCL27 expression is regulated by both p38 MAPK and IKKβ signalling pathways ', Cytokine Yearbook . https://doi.org/10.1016/j.cyto.2011.09.007
The skin-specific chemokine CCL27 is believed to play a pivotal role in establishing the inflammatory infiltrate characteristic for common inflammatory skin diseases. Through binding to the chemokine receptor 10 (CCR10), CCL27 mediates inflammation b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be56ab5bbba838070e0e06e6ee6973d7
https://pubmed.ncbi.nlm.nih.gov/21993219
https://pubmed.ncbi.nlm.nih.gov/21993219
Autor:
Tue Wenzel Kragstrup, Kristian Otkjaer, Søren R. Paludan, Helmut Holtmann, Matthias Gaestel, Claus Johansen, Knud Kragballe, Lars Iversen
Publikováno v:
PLoS ONE
Otkjaer, K, Holtmann, H, Kragstrup, T W, Paludan, S R, Johansen, C, Gaestel, M, Kragballe, K & Iversen, L 2010, ' The p38 MAPK regulates IL-24 expression by stabilization of the 3' UTR of IL-24 mRNA ', P L o S One, vol. 5, no. 1, pp. e8671 . https://doi.org/10.1371/journal.pone.0008671
PLoS ONE, Vol 5, Iss 1, p e8671 (2010)
Otkjaer, K, Holtmann, H, Kragstrup, T W, Paludan, S R, Johansen, C, Gaestel, M, Kragballe, K & Iversen, L 2010, ' The p38 MAPK regulates IL-24 expression by stabilization of the 3' UTR of IL-24 mRNA ', P L o S One, vol. 5, no. 1, pp. e8671 . https://doi.org/10.1371/journal.pone.0008671
PLoS ONE, Vol 5, Iss 1, p e8671 (2010)
Udgivelsesdato: 2010-null BACKGROUND: IL-24 (melanoma differentiation-associated gene-7 (mda-7)), a member of the IL-10 cytokine family, possesses the properties of a classical cytokine as well as tumor suppressor effects. The exact role of IL-24 in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::62256b86d86943c8277dae7b6db7280f
https://pubmed.ncbi.nlm.nih.gov/20072629
https://pubmed.ncbi.nlm.nih.gov/20072629
Autor:
Christian K. Holm, Marianne Hokland, Tue Wenzel Kragstrup, Kristian Otkjaer, Annette Jørgensen, Lars Iversen, Bent Deleuran
Publikováno v:
Kragstrup, T W, Otkjaer, K, Holm, C, Jørgensen, A, Hokland, M, Iversen, L & Deleuran, B W 2008, ' The expression of IL-20 and IL-24 and their shared receptors are increased in rheumatoid arthritis and spondyloarthropathy. ', Cytokine, vol. 41, no. 1, pp. 16-23 . https://doi.org/10.1016/j.cyto.2007.10.004
The purpose of this study was to analyze the expression of the two proinflammatory cytokines IL-20 and IL-24 and their shared receptors in rheumatoid arthritis and spondyloarthropathy. IL-20 was increased in plasma of rheumatoid arthritis patients co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::475bdf647252a35430376b44d3ce221b
https://pure.au.dk/ws/files/48584931/Cytokine_2008_Kragstrup.pdf
https://pure.au.dk/ws/files/48584931/Cytokine_2008_Kragstrup.pdf