Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kristian Leite"'
Autor:
Pretty Garg, Franziska Würtz, Fabian Hobbie, Klemens Buttgereit, Abhishek Aich, Kristian Leite, Peter Rehling, Sebastian Kügler, Mathias Bähr
Publikováno v:
Journal of Neuroinflammation, Vol 21, Iss 1, Pp 1-16 (2024)
Abstract Background Presence of autoantibodies against α-synuclein (α-syn AAb) in serum of the general population has been widely reported. That such peripheral factors may be involved in central nervous system pathophysiology was demonstrated by d
Externí odkaz:
https://doaj.org/article/e0c5f527c41447b8b5608a7f0795d2c4
Autor:
Kristian Leite, Pretty Garg, F. Paul Spitzner, Sofia Guerin Darvas, Mathias Bähr, Viola Priesemann, Sebastian Kügler
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 15 (2022)
α-synuclein (α-Syn) is intimately linked to synucleinopathies like Parkinson’s disease and dementia with Lewy bodies. However, the pathophysiological mechanisms that are triggered by this protein are still largely enigmatic. α-Syn overabundance
Externí odkaz:
https://doaj.org/article/24dc0e7485754e85828935a5cb57124f
Autor:
Johan Tolö, Grit Taschenberger, Kristian Leite, Markus A. Stahlberg, Gesche Spehlbrink, Janina Kues, Francesca Munari, Stefano Capaldi, Stefan Becker, Markus Zweckstetter, Camin Dean, Mathias Bähr, Sebastian Kügler
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 11 (2018)
α-Synuclein (α-Syn) is intimately linked to the etiology of Parkinson's Disease, as mutations and even subtle increases in gene dosage result in early onset of the disease. However, how this protein causes neuronal dysfunction and neurodegeneration
Externí odkaz:
https://doaj.org/article/d3472a5ad9ae4edd8e290304102884ef
Autor:
Sameehan Mahajani, Kristian Leite, Maryna Psol, Sebastian Kügler, Sofia Guerin Darvas, Mathias Bähr
Publikováno v:
Human Molecular Genetics. 30:247-264
Beta (ß)-synuclein (ß-Syn) has long been considered to be an attenuator for the neuropathological effects caused by the Parkinson’s disease-related alpha (α)-synuclein (α-Syn) protein. However, recent studies demonstrated that overabundant ß-S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec882cc475adc84a598dfcd8c224206d
https://doi.org/10.1093/hmg/ddab036
https://doi.org/10.1093/hmg/ddab036
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific Reports
The CTG trinucleotide repeat (TNR) expansion in Transcription factor 4 (TCF4) intron 3 is the main cause of Fuchs’ endothelial corneal dystrophy (FECD) and may confer an increased risk of developing bipolar disorder (BD). Usage of alternative 5′
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f441797c31ac89301409bab8a304c4d6
http://link.springer.com/article/10.1038/s41598-020-75437-3
http://link.springer.com/article/10.1038/s41598-020-75437-3
Autor:
Kalyan S. Chakrabarti, Mathias Bähr, Anupam Raina, Christian Griesinger, Sameehan Mahajani, Stefan Becker, Diana Voll, Sebastian Kügler, Kristian Leite, Sofia Guerin
Publikováno v:
Journal of Neurochemistry. 156:674-691
A contribution of α-Synuclein (α-Syn) to etiology of Parkinson´s disease (PD) and Dementia with Lewy bodies (DLB) is currently undisputed, while the impact of the closely related β-Synuclein (β-Syn) on these disorders remains enigmatic. β-Syn h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e15ed1f519922566a54caae4008b78d5
https://doi.org/10.1111/jnc.15134
https://doi.org/10.1111/jnc.15134
