Zobrazeno 1 - 10
of 161
pro vyhledávání: '"Kristian Kempe"'
Publikováno v:
Molecular Pharmaceutics. 20:2686-2701
Publikováno v:
Polymer Chemistry. 14:2054-2062
Aqueous solubility of poly(methylamide acrylate)s can be altered via modulation of the side chain spacer length between the polymer backbone and pendant amide functionality whereby a butyl spacer is sufficient to induce LCST behaviour (P(MAmBA)).
Publikováno v:
Biomaterials Science. 11:3159-3171
Poly((2-methyl-2-oxazoline)-grad-(2-phenyl-2-oxazoline)) and core-crosslinked micelles thereof are capable of inhibiting ferroptosis, a non-apoptotic iron-induced cell death mechanism.
Autor:
David Pizzi, James Humphries, Joshua P. Morrow, Ayaat M. Mahmoud, Nicholas L. Fletcher, Stefan E. Sonderegger, Craig A. Bell, Kristofer J. Thurecht, Kristian Kempe
Publikováno v:
Biomacromolecules. 24:246-257
Poly(2-oxazoline)s (POx) have received substantial attention as poly(ethylene glycol) (PEG) alternatives in the biomedical field due to their biocompatibility, high functionality, and ease of synthesis. While POx have demonstrated strong potential as
Publikováno v:
Lam, Y Y, Tan, A, Nowell, C J, Kempe, K & Boyd, B J 2023, ' Systematic Investigation of Metabolic Oligosaccharide Engineering Efficiency in Intestinal Cells Using a Dibenzocyclooctyne-Monosaccharide Conjugate ', ChemBioChem, vol. 24, no. 12, e202300144 . https://doi.org/10.1002/cbic.202300144
Metabolic oligosaccharide engineering (MOE) of cells with synthetic monosaccharides can introduce functionality to the glycans of cell membranes. Unnatural sugars (e. g., peracetylated mannose-azide) can be expressed on the cell surface with the azid
Autor:
Sarigama Rajesh, Meike N. Leiske, Victoria Leitch, Jiali Zhai, Calum J. Drummond, Kristian Kempe, Nhiem Tran
Publikováno v:
Journal of Colloid and Interface Science. 623:1142-1150
Autor:
Meike N. Leiske, Zihnil. A. I. Mazrad, Aykut Zelcak, Kanu Wahi, Thomas P. Davis, Joshua A. McCarroll, Jeff Holst, Kristian Kempe
Publikováno v:
Biomacromolecules. 23:2374-2387
The synthesis of new amino acid-containing, cell-specific, therapeutically active polymers is presented. Amino acids served as starting material for the preparation of tailored polymers with different amino acids in the side chain. The reversible add
Publikováno v:
Macromolecules. 55:3650-3660
Autor:
Fanmengjing Wang, David Pizzi, Yizhihao Lu, Kaiqiang He, Kristofer J. Thurecht, Matthew R. Hill, Philip J. Marriott, Mark M. Banaszak Holl, Kristian Kempe, Huanting Wang
Publikováno v:
Angewandte Chemie. 135
Chiral separation membranes have shown great potential for efficient separation of racemic mixtures into enantiopure components for many applications such as in food and pharmaceutical industries; however, scalable fabrication of membranes with both
Publikováno v:
Polymer Chemistry.
Polymer-based nanoparticle morphology and surface chemistry are important factors to consider when it comes to their stability, biocompatibility, and biodistribution. Poly(2-oxazoline)s and poly(2-oxazine)s have been shown to exhibit favourable physi