RNA-Guided Activation of Pluripotency Genes in Human Fibroblasts

Autor: Kai Xiong, Kristian Aabo Blichfeld, Poul Hyttel, Lars Bolund, Kristine K. Freude, Yan Zhou, Yonglun Luo

Publikováno v: Xiong, K, Zhou, Y, Blichfeld, K A, Hyttel, P, Bolund, L, Freude, K K & Luo, Y 2017, ' RNA-Guided Activation of Pluripotency Genes in Human Fibroblasts ', Cellular reprogramming, vol. 19, no. 3, pp. 189-198 . https://doi.org/10.1089/cell.2017.0006

Specific activation of endogenous genes can be achieved by programmable artificial transcription factors (ATFs). In this study, we compared two artificial, programmable, clustered regularly interspaced short palindromic repeats (CRISPR)-based, ubiqui

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bf25ec119dabbf3e8bcf65d4024583d
https://pure.au.dk/portal/da/publications/rnaguided-activation-of-pluripotency-genes-in-human-fibroblasts(3b5c5a62-3e2d-42f7-be16-b8f1273ef36b).html

Phenotypic Growth Expression of Mixed Tumors Grown in Nude and Syngeneic Mice1

Autor: Kristian Aabo, Mogens Spang-Thomsen, Lars Vindeløv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::2d69a40365f992a47952bd20daf17f50
https://doi.org/10.1159/000413319

Megakaryocytes in Pulmonary Blood Vessels

Autor: Knud Bendix Hansen, Kristian Aabo

Publikováno v: Acta Pathologica Microbiologica Scandinavica Section A Pathology. :293-295

In a study of 71 autopsies in patients with malignant haematological disorders (55 leukaemias and 16 multiple myelomas) we found an increased number of megakaryocytes in the lung capillaries in only one of 55 cases of leukaemia (43 acute and 12 chron

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::217b5b4871ba7afdf3621edfa1949274
https://doi.org/10.1111/j.1699-0463.1978.tb02046.x

Interaction between three subpopulations of Ehrlich carcinoma in mixed solid tumours in nude mice: evidence of contact domination

Autor: Kristian Aabo, Mogens Spang-Thomsen, Lars Vindeløv

Publikováno v: British Journal of Cancer

Clonal interaction between three subpopulations of Ehrlich carcinoma were studied during growth as mixed solid tumours and as ascites tumours in immune-incompetent nude NMRI mice. The tumour cell lines differed in DNA content as determined by DNA flo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af4d6562003a8ff4d497dae4ce921bf5
https://doi.org/10.1038/bjc.1994.255

Dual Modulation of UFT with leucovorin and hydroxyurea in metastatic colorectal cancer

Autor: Flemming Hansen, Anders Jakobsen, Kristian Aabo, Per Pfeiffer, Erik Sandberg

Publikováno v: Jakobsen, A, Pfeiffer, P, Hansen, F, Sandberg, E & Aabo, K 2001, ' Dual Modulation of UFT with leucovorin and hydroxyurea in metastatic colorectal cancer ', Acta Oncologica, vol. 40, no. 1, pp. 63-66 . < http://www.ncbi.nlm.nih.gov/pubmed/?term=Dual+Modulation+of+UFT+with+leucovorin+and+hydroxyurea+in+metastatic+colorectal+cancer >

The aim of the study was to investigate the possibility of dual modulation of UFT with leucovorin and hydroxyurea in a phase II trial of metastatic colorectal cancer. A total of 77 patients with measurable disease were included. UFT (300 mg/m2) was g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6be31ea9d55992cfae915ce8d0df291e
https://pure.au.dk/portal/da/publications/dual-modulation-of-uft-with-leucovorin-and-hydroxyurea-in-metastatic-colorectal-cancer(16d6c070-9561-11da-bee9-02004c4f4f50).html